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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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39.

STABILITY INDICATING RP-HPLC METHOD FOR ESTIMATION OF DORAVIRINE, LAMIVUDINE AND TENOFOVIR DISOPROXIL FUMARATE IN PHARMACEUTICAL DOSAGE FORM

Doravirine, Lamivudine, and Tenofovir Disoproxil Fumarate belong to the class of anti-viral drugs and have been widely used in the treatment of HIV-I infection. Doravirine is a novel non-nucleoside reverse transcriptase inhibitor used in the combination of Lamivudine and Tenofovir Disoproxil Fumarate to effectively treat HIV/AIDS by overcoming the common resistance mutations without any possible d...

K. Vasantha * and G. Devala Rao

School of Pharmacy, Career Point University, Kota, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.13(9).3737-48

3737-3748

118

59

32.

PREDICTION OF POTENTIAL INHIBITORS SIMILAR TO REMDESIVIR (GS-5734) AGAINST 7BTF SARS COV 2 RNA DEPENDENT RNA POLYMERASE – AN IN-SILICO APPROACH

The novel Corona Virus Disease - 19 (COVID-19) is a Contagious disease spreading among Animals and Humans, a Severe Acute Respiratory Syndrome CoronaVirus-2 (SARS CoV2). The First case was identified in Wuhan, China as the disease has unfolded worldwide to the continuing pandemic. It created more infected cases and deaths worldwide, creating an urge for newer drugs of manipulate the Ongoing Pandem...

K. Akila *, B. Pooja and R. Sharmila

Department of Biotechnology and Bioinformatics, Bishop Heber College (Autonomous), Tiruchirappalli, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.13(11).4628-35

4628-4635

118

78

31.

DEVELOPMENT AND VALIDATION OF UV SPECTROMETRIC METHOD OF ECONAZOLE NITRATE CO-CRYSTAL LOADED IN GEL FORMULATION

A simple, fast, inexpensive, and reliable UV spectrometric method was developed and validated to quantify Econazole Nitrate incorporated in topical gel in the form of co-crystal. This article presents the development and validation of different methods for quantification of Econazole nitrate co-crystal loaded in the topical gel as per ICH [Q2(R1)] guidelines. In method-A, the standard and sample s...

Priyanka S. Gala *, Mohammad Wais and Ojaswi Ghadge

Department of Pharmaceutics, HK College of Pharmacy, Oshiwara, Jogeshwari [W] Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.13(12).5057-67

5057-5067

118

60

21.

COMPARISON OF FUNCTIONAL OUTCOME AND PAIN RELIEF BETWEEN STEROID INJECTION AND PLATELET RICH PLASMA INJECTION IN EARLY OSTEO ARTHRITIS KNEE

Introduction: Osteoarthritis Knee (OA) is the most common form of joint disability in elderly individuals. Various treatment modalities have been established for OA. This study is to compare the functional outcome and pain relief following IA (intraarticular) steroid versus PRP (platelet-rich plasma) injection. Methods: In this study 30, patients were selected and segregated into two groups 15 eac...

V. Aakash, N. Adhishwar Kumaran, Arun Vignesh and Vignesh

Department of Orthopedics, Saveetha Medical College and Hospital, Thandalam, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.13(12).4985-90

4985-4990

118

65

31.

IN-VITRO SCREENING OF EXTRACTS OF CENTELLA ASIATICA (LINN) URBAN FOR ANTIBACTERIAL PROPERTIES

Centella asiatica (Linn) Urban, a herb of immense medicinal properties, has been widely used by traditional healers in the treatment of skin diseases, mental fatigue, anxiety, rheumatism, eoilepsy and leprosy. In the present investigation, the antibacterial activity of ethanol, acetone and aqueous extracts of Centella asiatica were tested in-vitro against seven bacterial species viz. Staphylococcu...

Lincy Sara Varghese * and Krishna Suresh

Department of Botany, Bishop Kurialacherry College for Women, Amalagiri P.O., Kottayam, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.13(9).3668-74

3668-3674

117

61

21.

DEVELOPMENT AND EVALUATION OF FAST-DISSOLVING TABLETS OF AN ANTI-GOUT DRUG BY SUBLIMATION METHOD

The purpose of the current research was to formulate and evaluate patient-friendly allopurinol solid dispersion based fast-dissolving tablets using a sublimation technique in order to accomplish rapid drug dissolution. In the present study, an effort was made to fasten the release of allopurinol from oral tablet dosage form by the conversion of the drug into solid dispersion form followed by furth...

SK. Arifa Begum *, G. Joshua, K. Bharath and B. Akash

Department of Pharmaceutics & Biotechnology, KVSR Siddhartha College of Pharmaceutical Sciences, Siddhartha Nagar, Vijayawada, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.13(9).3579-88

3579-3588

117

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38.

DEGREDATION OF PERCHLORATE WITH PHENOL AS A SOLE CARBON SOURCE BY AN ISOLATED STRAIN PSEUDOXANTHOMONAS SP.

Phenol was used as a sole carbon source for the perchlorate biodegradation as reported for the first time. Isolated bacterial species Pseudoxanthomonas sp. isolated from a sewage sludge consortium was found to reduce perchlorate while taking phenol as electron acceptor. The growth and perchlorate degradation were analyzed in a batch system along with the degradation profile of phenol by the microb...

A. Ghosh *, K. Pakshirajan and P. K. Ghosh

Department of Microbiology and Biotechnology, Sister Nivedita University, West Bengal, Kolkata, India.

DOI: 10.13040/IJPSR.0975-8232.13(9).3723-36

3723-3736

117

45

37.

VISCOMETRIC STUDY OF SYNTHESIZED DILTIAZEM-VANADIUM (V) COMPLEX IN NON-AQUEOUS SOLVENTS

In the present research work, measurement of viscometric parameters - Density, Molar Volume, Apparent Molar Volume, Viscosity, Specific Viscosity, and Fluidity of synthesized Vanadium (V) complex of commercial antihypertensive drug, Diltiazem has been reported in non-aqueous solvents of varying compositions. Composition of non-aqueous solvents selected for study is 20% and 40% methanol-water mixtu...

R. Shrivastava, M. Kapoor * and M. Tekriwal

Department of Chemistry, Faculty of Basic and Applied Sciences, Vivekananda Global University, Jaipur, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.13(10).4154-58

4154-4158

117

66

34.

IDENTIFICATION AND ISOLATION OF BIOACTIVE COMPONENTS USING GC-MS, UV VISIBLE, FTIR, HPLC, HPTLC AND ANTIOXIDANT ACTIVITY PRESENT IN ETHANOLIC EXTRACT OF INDIAN SPICES MIXTURE

Introduction: The spices, despite their taste and flavor, have certain therapeutical uses from ancient days. For this research work, we have chosen some selected spices indefinitely amount. Materials and Methods: Phytochemical analysis, mineral estimation Characterisations such as GC-MS, UV Visible & FTIR spectroscopy, HPLC, HPTLC, and Antioxidant activity were carried out. Results & Discu...

B. Ramya *, V. Shanmuga Priya and S. Ranjani

PG Department of Biochemistry, Holy Cross College (Autonomous), Trichy, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.13(11).4641-55

4641-4655

117

84

6.

VALIDATED SPECTROSCOPIC AND CHROMATOGRAPHIC TECHNIQUES FOR QUALITY CONTROL ANALYSIS OF APIGENIN IN HERBAL MEDICINES

The herbal medicines have been largely used since form several thousands of years in all developing and developed countries in the primary health care of community and society. Flavonoids are the class of polyphenolic secondary metabolites, which are mainly found in plants. Apigenin is a flavonoid which shows several pharmacological activities and used effectively for the management and treatment ...

Shweta B. Chougule, Arati B. Jivaje, V. S. Mannur and Shailendra S. Suryawanshi *

Department of Pharmaceutical Chemistry, KLE College of Pharmacy Belagavi, KLE Academy of Higher Education and Research, Belagavi, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.13(12).4857-64

4857-4864

117

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