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WOUND HEALING EFFICACY OF A POLYHERBAL TOPICAL GELIN RAT MODELS OF EXCISION WOUND, INCISION WOUND, AND THERMAL BURN INJURY
Background: In Ayurvedic literature, Aloe vera, turmeric, honey, karanj oil, and cow ghee are documented for medicinal properties like anti-infective, anti-inflammatory, anti-oxidant, anti-coagulant and wound recovery. Objective: In this study, we aimed to evaluate the efficacy of a topical gel containing Aloe vera extract, turmeric, honey, karanj oil, and cow ghee for wound healing. Methods: Topi...
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SIDDHA DRUGS AND DISCIPLINES FOR THE MANAGEMENT OF COMPUTER VISION SYNDROME (CVS) – A REVIEW
In this advanced technological world, the computer has become an indispensable piece of equipment in both office and home. Visual and ocular problems have recently been reported as the most frequently occurring health problem among computer users. Prolonged exposure to radiofrequency radiation affects eyesight and indirectly affects the whole body function. The herbal supplements that improve eye ...
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STRUCTURAL AND FUNCTIONAL ABNORMALITIES ASSOCIATED WITH HIGH FRUCTOSE DIET-INDUCED METABOLIC SYNDROME IN WISTAR ALBINO RATS
Purpose of the study: To assess Structural and functional abnormalities associated with High fructose diet-induced Metabolic syndrome in wistar albino rats. Materials and Methods: Metabolic syndrome is induced in adult male Wistar albino rats by feeding a combination of High Fructose Diet (55%) and Fructose enriched water (15%) for 75 days and kept as group 2 or HFrD Group. Normal male Wistar albi...
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EFFECT OF HORMONAL CONTRACEPTIVES ON INFLAMMATORY BLOOD BIOMARKER C-REACTIVE PROTEIN
To compare the effect of combined oral contraceptive (COC) and progesterone-only injectable contraceptive (PIC) on the inflammation, we recruited 47 female participants (16 to 43 years old) in 3 groups: control participants (n=10), COC users (n=16) and PIC users (n=21). Using ELISA and Latex agglutination methods, we measured the effect of hormonal contraceptives on the inflammatory blood biomarke...
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IN-VIVO MODELS OF NON-ALCOHOLIC FATTY LIVER DISEASE
Non-alcoholic fatty liver disease (NAFLD), a common chronic liver condition, is high in developed nations. One of the factors leading to chronic liver disease and cryptogenic cirrhosis has been identified as NAFLD. Multiple risk factors, including obesity, insulin resistance, diabetes mellitus, hyperlipidemia, and hypertension-related cardiovascular disease, contribute to the development of NAFLD....
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DEVELOPMENT OF VALIDATED RP-HPLC METHOD FOR ESTIMATION OF CAPECITABINE BY QBD APPROACH
It belongs to the group of medications called as anti-metabolites and is a fluoropyrimidine carbonate with anti-cancer properties. The chemotherapy drug capecitabine is taken orally and is used to treat metastatic colorectal and breast cancers. A review of the literature reveals several analytical techniques have been developed for Capecitabinein single and combined with other drugs. No QbD-assist...
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IDENTIFICATION OF BIOMARKERS OF OXIDATIVE STRESS IN FRESHWATER FISH (CIRRHINUSREBA) AFTER EXPOSURE TO INDUSTRIAL WASTE IN KANPUR
Exposure to heavy metals may modify fish behavior, metabolism, physiology, growth, and reproduction. They are also responsible for introducing genetic and teratogenic effects in fish. Now a day’s in many regions; fish production is decreased due to the occurrence of diseases caused by different pathogens in aquaculture. The increasing level of trace elements is dangerous for fish growth and repr...
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THERAPEUTIC CARRIERS FOR THE VAGINAL DELIVERY OF ANTI-HIV DRUG
HIV is a pandemic disease that is rapidly spreading across the world. The current review's objective is to present how comprehensive various advanced anti-HIV drug delivery systems are. The use of a new drug delivery system helps in overcoming the challenges of dosage form growth, such as drug instability, insolubility, and restricted entrapment. Several delivery routes for ARV therapy have been i...
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GC-MS ANALYSIS OF METHANOL EXTRACT OF CLEOME BURMANNI W. & A. (CLEOMACEAE)
Plants are rich sources of chemical compounds of high therapeutic value and screening plants for such bioactive compounds is the order of the day. First and foremost, it appears sensible to probe into the chemical reserves of abundantly available but rarely studied plants. The present study was carried out to determine the presence of phytochemicals in a common roadside weed, Cleome burmanni using...
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SYNTHESIS AND ANTI-CONVULSANT ACTIVITY OF NOVEL BENZHYDRYL PIPERAZINE DERIVATIVES
A series of 1 - (4 -Benzhydryl piperazin-1-yl) -3-(mono -substituted) propan-1-one (7c-i) and N - (substituted) - 2 - (4 –benz-hydrylpiperazin – 1 - yl) acetamide (7a, 7d) were designed, synthesized and evaluated for their anticonvulsant and neurotoxicity activity. The chemical structure of the synthesized compounds was elucidated by spectral and elemental analysis. Compounds like 7d, 7c, and ...
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