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IN-VIVO MODELS OF NON-ALCOHOLIC FATTY LIVER DISEASE
Non-alcoholic fatty liver disease (NAFLD), a common chronic liver condition, is high in developed nations. One of the factors leading to chronic liver disease and cryptogenic cirrhosis has been identified as NAFLD. Multiple risk factors, including obesity, insulin resistance, diabetes mellitus, hyperlipidemia, and hypertension-related cardiovascular disease, contribute to the development of NAFLD....
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A COMPREHENSIVE REVIEW ON REGULATION CONCERNS FOR IMPORT AND EXPORT OF PHARMACEUTICAL DRUGS AND GENETIC PRODUCTS IN INDIA, BRITAIN AND SWITZERLAND
Biopharmaceutical technologies used to create biodegradable materials from biological agents fall within a broad spectrum. The production of bioproducts has grown cleaner and more dependable with the adoption of novel biotechnological approaches. The original study objective was to investigate the legal difficulties surrounding the purchase and sale of biological as well as pharmaceutical products...
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A COMPARATIVE ANIMAL STUDY OF ANALGESIC EFFECTS OF TRANDOLAPRIL AND NIMODIPINE IN MICE USING EDDY’S HOT PLATE
Angiotensin II from the renin-angiotensin system is proposed to be pro-inflammatory induces reactive oxygen species, nuclear factor kappa B. It sensitizes pain receptors to mediators of pain (via PGE2). ACEI block these actions increase endogenous opioids by inhibiting enzyme enkephalinase. Voltage-gated calcium channels (VGCC) causing calcium influx are involved in exocytosis of synaptic vesicle ...
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EFFECT OF SUGARCANE BAGASSE AS A SOURCE OF CARBON FOR ɑ-AMYLASE ENZYME AND ANTIBACTERIAL COMPOUND PRODUCING DIFFERENT TYPES OF WILD FILAMENTOUS FUNGI
The present investigation screening and characterization of α-amylase and antimicrobial compound producing filamentous fungi is used for extensive commercial applications in various sectors and is highly demanded in the Biotech industry. The results reveal that out of the carbon substrates alone, sugarcane bagasse with a combination of Tween-80 was found to yield maximum α-amylase (151.76 IU) un...
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TELMISARTAN NIOSOMES DESIGN, DEVELOPMENT AND CHARACTERIZATION
Telmisartan has a strong, nonpeptide antagonist with long-acting angiotensin II type-1 (AT 1) receptor to treat essential hypertension. It is classified as a BCS class II medication, meaning it has poor solubility and high permeability. Because of their capacity to minimise toxicity and change bioavailability, niosomes are becoming increasingly essential in medication delivery. Telmisartan-loaded...
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KNOWLEDGE OF ANTIMICROBIAL RESISTANCE AND ANTIMICROBIAL PRESCRIPTION AMONG DENTAL PRACTITIONERS IN CHENNAI CITY- A CROSS-SECTIONAL STUDY
Introduction: Most human oro-facial infections originate from odontogenic infections, and prescribing antimicrobial has become a ubiquitous phenomenon. The World Health Organization (WHO) has recognized the inappropriate, indiscriminate and irrational use of antimicrobials leading to antimicrobial resistance. Aim & Objective: To assess the knowledge of antimicrobial resistance and antimicrobia...
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HEAVY METAL CONTENTS AND ASSOCIATED HEALTH RISK OF SOME GHANAIAN AND ASIAN HERBAL DRUGS
This study looked at heavy metal levels in selected registered herbal drugs of Asian and unregistered Ghanaian herbal drugs sold in Kumasi. It examined the health risks of the metals. It provided authorities with data to ensure that herbal drugs are strictly monitored and their metal levels evaluated to safeguard patrons' health. Dry ashing method was used on 10g of each of the herbal drug samples...
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A REVIEW ON THE CURRENT STATUS OF MULTI-DRUG RESISTANT STAPHYLOCOCCUS AUREUS AND ITS FUTURE PROSPECTS
Infectious diseases are the most significant cause of fatalities worldwide. Staphylococcus aureus could be a common human infective microorganism that will trigger various infectious diseases, like soft tissue and skin infections, osteomyelitis, bacteremia, endocarditis, and fatal respiratory illnesses. In recent decades, because of the evolution of microorganisms and the abuse of antibiotics, the...
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INDIGENOUS AND UNDER-UTILISED OIL SEEDS OF BOTSWANA: PROXIMATE COMPOSITION, PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY
Proximate composition, qualitative screening for phytochemicals (terpenoids, steroids, tannins, oxalates, coumarins, phenols, saponins, and flavonoids) and antioxidant properties in four selected indigenous oilseeds: morama (Tylosema esculentum), mongongo (Schinziophyton rautenenii), mogose (Bauhinia petersiana) and kgengwe (Citrulus lanatus (Thunb.) Mansf.) from Botswana was examined. A significa...
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SCREENING OF PGPR TRAITS AND MONOCROTOPHOS PESTICIDE DEGRADATION PROPERTIES OF ACTINOBACTERIAL ISOLATES
Bioremediation of organic compounds and heavy metals has been recognized to be a successful and effective technique in rhizoremediation of soil toxicity using the beneficial microbes which produce different metabolites and enzymes to degrade the toxic compounds/ pesticides available in the soil. In the present study, actinobacterial isolates were explored and identified for bioremediation of soil ...
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