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COMPARISON OF EFFICACY OF DEXMEDETOMIDINE AND TRAMADOL FOR PROPHYLACTIC USE IN POST SPINAL ANAESTHESIA SHIVERING. A PROSPECTIVE RANDOMIZED CONTROLLED STUDY
Background: Shivering is one of the most troublesome and distressing experiences for the patient encountered intraoperatively following spinal anaesthesia. Tramadol is very commonly used in clinical practice for post-spinal shivering but has side effects. The study aimed to compare the efficacy of dexmedetomidine with that of tramadol for prophylactic use in post-spinal anaesthesia shivering. Meth...
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OCULAR EFFECTS OF WATER EXTRACT OF OCIMUM GRATISSIMUM IN RABBITS
The water extract of Ocimum gratissimum, L Lamiaceae, used in traditional medicine and local food spice, was evaluated for its ocular effect using three ocular parameters, pupil diameter (PD), corneal reflex (CR) and pupillary light reflex (PLR). The phytochemical tests were performed on the pulverized leaves, which were used to ascertain the distribution pattern of some possible bioactive agents ...
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DESIGN, DEVELOPMENT AND EVALUATION OF STABLE VALSARTAN NANOCRYSTALS WITH CHITOSAN USING MICROWAVE-ASSISTED GRINDING NANOTECHNOLOGY
Solubility and stability are the limiting steps for almost all drugs in the pharmaceutical field toward bioavailability. In the present investigation, microwave reacts with the crystallization solvent to change their crystalline state to stable and highly soluble nanocrystals. Microwave Assisted Grinding Nanotechnology (MAGN) was used to prepare stable nanocrystals of Valsartan, BCS class II, by t...
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MICROSPHERES: A NOVEL APPROACH FOR DELIVERY OF ANTIHYPERLIPIDEMIC DRUGS
Microsphere drug delivery is a novel drug delivery approach for sustaining and controlling the rate and release of active pharmaceutical ingredients. Microspheres are the choice of drug delivery for delivering the drug at a specific site to release the encapsulated drug to treat various diseases. Microspheres drug delivery is an attractive dosage form in terms of its flexibility and sustaining the...
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MEDICINAL PLANTS USED IN RICE BEER STARTER CULTURE BY DIFFERENT TRIBES IN ASSAM: AN ETHNOBOTANICAL SURVEY
The study represents the ethnobotanical information of the medicinal plants used by the six major communities of Assam, namely Mishing, Deori, Ahom, Tiwa, Bodo and Rabha, for better understanding of their local beliefs, customs, and tradition in the preparation of traditional rice beer starter culture. A semi-structured questionnaire was used focusing on the local names of the plants used in a sta...
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A COMPREHENSIVE REVIEW ON REGULATION CONCERNS FOR IMPORT AND EXPORT OF PHARMACEUTICAL DRUGS AND GENETIC PRODUCTS IN INDIA, BRITAIN AND SWITZERLAND
Biopharmaceutical technologies used to create biodegradable materials from biological agents fall within a broad spectrum. The production of bioproducts has grown cleaner and more dependable with the adoption of novel biotechnological approaches. The original study objective was to investigate the legal difficulties surrounding the purchase and sale of biological as well as pharmaceutical products...
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A CUMULATIVE REVIEW ON THERAPEUTICFLORAE USED TOTREAT DIABETES MELLITUS
Diabetes Mellitus is a chronic ailment characterized by clinical manifestations like hyperglycaemia. The development of novel drugs is based on the understand ding of insulin resistance and oxidative damage leading to secondary complications of diabetes such as Retinopathy, Nephropathy etc. In the modern era, there are numerous allopathic drugs available for the treatment of the ailment. Herbs inc...
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ANTI-INFLAMMATORY EFFECT OF DISEASE-MODIFYING ANTI-RHEUMATIC DRUG, LEFLUNOMIDE: A REVIEW
The epidemiology, pathophysiology, clinical capabilities, diagnosis and scientific route of rheumatoid arthritis (RA) and the function of disorder-editing anti-rheumatic tablets (DMARDs) in its remedy are reviewed. RA, a giant disorder affecting humans of all races and sexes around the sector, has an unknown and perhaps multifactorial etiology. Conflicting proof supports RA's immune-complex, infec...
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DIGITAL SCREEN USE AND DRY EYE DISEASE: THE ROLE OF MUCINS, DIETARY NUTRIENTS AND PHYTOCHEMICAL CONSTITUENTS IN DRY EYE DISEASE RELIEF
Dry eye disease (DED) is one of the most common conditions in today’s digitalized society. DED is associated with decreased tear production, an unstable tear film, and ocular inflammation. Due to the COVID-19 pandemic, the use of digital screens (computers, laptops or smartphones) for work, study or entertainment has increased. As a result, the constant use of digital screens affects the eyes an...
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EFFECT OF EDUCATIONAL INTERVENTION ON MATERNAL KNOWLEDGE IN USE OF ANTIBIOTICS IN ACUTE RESPIRATORY INFECTIONS AMONG UNDER FIVE CHILDRENIN URBAN FIELD PRACTICE AREA OF MEDICAL COLLEGE BANGALORE
Background: Acute respiratory infections are the most important cause of mortality and morbidity among under-five children in developed and developing countries in the world. There is lack of awareness/ knowledge among parents regarding antibiotic use in children for minor respiratory ailments. Hence, the present study was undertaken. Methods and Methodology: After taking institutional ethical cle...
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