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FORMULATION OF HERBAL GEL FOR POTENTIAL ANTIBACTERIAL ACTIVITY AGAINST PSEUDOMONAS AERUGENOSA
The present work deals with the formulation of containing aqueous extract of Tectona grandis (Teak) Leaves and prepared formulation against some Gram-positive and Gram-negative bacteria. The antibacterial activity of various T. grandis leaves extracts was measured by determining minimum inhibitory concentration (MIC) by cube dilution method and zone of inhibition by disc diffusion method agains...
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EFFECT OF PARATHYROID HORMONE LEVELS ON PERIODONTAL STATUS IN PREGNANT WOMEN: A REVIEW
Periodontitis is a multifactorial disease. It has several associations with hormonal fluctuations; the body undergoes several physiological hormonal mechanisms. In several physiological conditions, hormonal fluctuations have been observed. One such condition is pregnancy. Several hormones are at play during pregnancy; one such hormone is PTH. Parathyroid hormone is essential to increase the matern...
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DETECTION OF STREPTOCOCCUS MUTANS ASSOCIATED WITH DENTAL CARIES AMONG ADULTS IN JEDDAH PROVINCE
Dental caries is one of the serious bacterial diseases of the oral cavity caused by diverse Streptococcus species. Streptococcus mutans strains displayed remarkable genotypic and phenotypic diversity. Glucosyl transferase genes are recognized as essential enzymes leading to biofilm production, the destruction of the ecosystem of normal bacterial communities, and the development of dental caries. T...
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PREPARATION AND EVALUATION OF FLOATING MICRO BEADS FOR GASTRO RETENTIVE DRUG DELIVERY SYSTEM OF ANTIULCER DRUG
The objective of the present investigation was to develop an alginate-HPMC K4M microbead-based gastro-retentive drug delivery system incorporating Famotidine for the treatment of gastrointestinal ulcers. The 32 full factorial designs were used for the optimization of famotidine-loaded floating microbeads. Two factors were evaluated, each at 3 levels; experimental trials were performed for all nine...
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ANTIDIABETIC, ANTIHYPERLIPIDEMIC, ANTIOXIDANT, HEPATOPROTECTIVE AND RENAL PROTECTIVE EFFECT OF LUFFA CYLINDRICA EXTRACT AGAINST THE STREPTOZOTOCIN-INDUCED DIABETES MELLITUS IN RATS
The main objective of the current study was to see whether SG peel methanolic extract had antidiabetic and hepatoprotective results in streptozotocin-induced diabetic rats. Streptozotocin was administered intraperitoneally to rats to trigger diabetes. When rats had an elevated blood sugar level three days after acquiring streptozotocin, it was determined that they were diabetic. Diabetic rats were...
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INFLUENCE OF CULTURAL PARAMETERS ON THE PRODUCTION OF BIOACTIVE METABOLITES BY STREPTOMYCES RECTIVERTICILLATUS VJMS-8 ISOLATED FROM SOUTH COASTAL REGIONS OF ANDHRA PRADESH, INDIA
Adaptation of marine actinobacteria to extreme climatic conditions such as high salinity, high pressure and high temperature has modified their physiological conditions to survive and elaborate novel bioactive metabolites. Among the different actinobacterial strains isolated from coastal regions of Guntur District, Andhra Pradesh, India, one potent strain with broad-spectrum antagonistic activity ...
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IDENTIFICATION OF FUNGAL ENDOPHYTES FROM THE LEAVES OF CLEISOSTOMA TENUIFOLIUM: AN EPIPHYTIC ORCHID
Distinctive groups of fungi are involved in the symbiotic association with epiphytic orchid. We have isolated endophytic fungi from Cleisostoma tenuifolium epiphytic orchid found in the Western Ghats and used morphological criteria as well as molecular techniques to identify these fungi. Characterization of these fungi was done by analyzing the quantified genomic sequences, and then identification...
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COMPARISON OF EFFICACY OF DEXMEDETOMIDINE AND TRAMADOL FOR PROPHYLACTIC USE IN POST SPINAL ANAESTHESIA SHIVERING. A PROSPECTIVE RANDOMIZED CONTROLLED STUDY
Background: Shivering is one of the most troublesome and distressing experiences for the patient encountered intraoperatively following spinal anaesthesia. Tramadol is very commonly used in clinical practice for post-spinal shivering but has side effects. The study aimed to compare the efficacy of dexmedetomidine with that of tramadol for prophylactic use in post-spinal anaesthesia shivering. Meth...
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NANOCOSMECEUTICALS: AN IMMERGING TREND IN PHARMACY
The global market size was valued at $ 380.2 billion in 2019 and is projected to reach $463.5 billion by 2027, registering a CAGR of 5.3% from 2021 to 2027. Cosmetics have become an in-dispersible feature of the modern lifestyle. The use of cosmetics has increased in males and women in daily routine, which complements the growth of global cosmetic market demand. The skin care industries are trying...
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THE QUANTITATIVE ANALYSIS OF METABOLITES FROM SELECTED CHENOPODIUM SPECIES
Chenopodium album L., Chenopodium murale L., and Chenopodium giganteum L. are annual herbs with ethno-medicinal value. The present study investigates the primary and secondary metabolites quantification of Chenopodium species. The quantitative estimation of bioactive molecules from the root, stem, and leaves showed the presence of proteins, carbohydrates, starch, phenols, and flavonoids. However, ...
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