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HISTORICAL PERSPECTIVE OF LEAD POISONING AND THERAPEUTIC APPROACH OF GARLIC (ALLIUM SATIVUM) AGAINST VARIOUS HUMAN ALIMENTS
Lead comes in a category of toxic heavy metal which acts as a pollutant when present in high concentration in the environment and cause severe effects on the human body. Due to its continuous use its level increases and serves as a serious threat for the society. Lungs and skin are the first organs which get affected by Lead toxicity. Lungs are the most important and sensitive part of human ther...
1860
1986
A COMPREHENSIVE GUIDE TO THE PATHOPHYSIOLOGY OF DIABETES MELLITUS & INNOVATIONS IN THE TREATMENT
Diabetes mellitus is a chronic metabolic disorder characterized by high levels of glucose in blood due to non-secretion of insulin or insulin insensitivity. Diabetes mellitus can cause many complications, acute complications include non ketotic hyperosmolar coma and diabetic ketoacidosis. Different types of diabetes mellitus are available – Type 1 diabetes mellitus (hormone dependent diabetes) a...
1859
868
EVALUATION OF ANTI-INFLAMMATORY AND ANTI-DIABETIC EFFECTS OF DIFFERENT FRACTIONS OF HOLARRHENA PUBESCENS (BUCH.- HAM.) WALL. SEED EXTRACT
Inflammation is a chemical-mediated defense mechanism of body. Inflammatory process is also associated with development of various diseases like rheumatoid arthritis, psoriasis, atherosclerosis, and diabetes. Diabetes mellitus is a most common and life-threatening health problem in today’s date. Several marketed anti-diabetic drugs are characterized with side effects. Hence there is a need to se...
1859
1021
COMPARISON OF ANTIOXIDANT POTENTIAL OF FRESH AND MARKETED SAMPLES OF MEDICINAL PLANT- ECLIPTA ALBA
The present study aimed at comparing the antioxidant potential of three different samples of Eclipta alba-fresh plant, marketed leaf powder (packaged in sealed containers), and marketed whole plant (sold in open bags). The presence of alkaloids, saponins, triterpenes, terpenoids, tannins, steroids, flavonoids, glycosides was confirmed in all three samples. Fresh plant samples showed a higher antio...
1859
1261
DEVELOPMENT AND IN-VITRO EVALUATION OF EMBELIN (A PHYTOCONSTITUENT) LOADED PHYTOSOME COMPLEX
Embelin was one of active constituents of Embelia ribes Burm. f. Embelin has been reported to possess many pharmacological effects. The studies as was perform to enhance the bioavailability of poorly water soluble embelin, reduce the dose of Embelin, prevent the degradation of Embelin in the GIT. For this, phytosome, a novel drug delivery system, was adopted. Total six Embelin loaded phytosome com...
1858
1010
A CASE REPORT ON ANOREXIA NERVOSA
Anorexia nervosa (AN) is a life-threatening condition with the highest mortality rate of all psychiatric disorders. The core physiological features of ANare the extreme overvaluation of shape and weight. Severe AN causes cardiovascular complications and majorly refeeding syndrome. The prominent features of refeeding syndrome include severe hypo-phosphatemia, hypokalemia and hypomagnesia, and other...
1858
1436
IN -VIVO EVALUATION OF ABIES PINDROW AS AN ANTI-DIABETIC PLANT
Background: The present study was carried to evaluate the phytochemical, antioxidant, and anti-diabetic potential of Abies pindrow leaf extracts. Methods: The extracted leaf samples of Abies pindrow in methanolic and hydroalcoholic solutions were evaluated for phytochemical and antioxidant activities. In-vitro antioxidant activity of both test samples was calculated by DPPH radical scavenging capa...
1857
1025
AN IN-SILICO APPROACH TO DRUG DESIGNING ON NOVEL TARGET FOR TUBERCULOSIS CAUSED BY MYCOBACTERIUM TUBERCULOSIS
Worldwide, Tuberculosis (TB) remains the most frequent and important infectious disease caused by Mycobacterium tuberculosis (Mtb). TB Structural Genomics Consortium (TBSGC) reported 79,144 deaths and 26.9 lakh cases in 2019 (WHO). Although tuberculosis is a curable disease, the chances of a cure become slim as the disease becomes multidrug-resistant, and the situation gets even worse as the disea...
1857
980
EVALUATION OF IN-VITRO ANTIFUNGAL POTENTIALITIES AND GC/MS SPECTROSCOPIC APPROACH OF CLEISTANTHUS COLLINUS (ROXB.) BENTH. EX. HOOK. F.
India is the home to the familiar plant Cleistanthus collinus (Roxb.) Benth. ex Hook. F (Euphorbiaceae) has great ethnomedicinal and therapeutic applications. The present study was designed to assess the phytochemical profile and investigate the antifungal effectiveness of leaf, bark and fruit extracts by using the agar well diffusion method. All crude extracts from leaf, bark, fruit and fractions...
1856
1214
ANTIMYCOTIC ACTIVITY OF LEAD OXIDE (PbO) NANOPARTICLES
Antimycotic activity of Lead oxide (PbO) nanoparticles prepared by the bio-safe method was evaluated for rot causing fungi. It was observed from the study that all the concentrations of nanoparticles brought about significant inhibition in the spore germination and mycelial growth of all the rot causing fungi. However, the highest inhibition in the germination of all the test fungi was observed at...
1855
1029