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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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26.

EVALUATION OF ANTI-INFLAMMATORY AND ANTI-DIABETIC EFFECTS OF DIFFERENT FRACTIONS OF HOLARRHENA PUBESCENS (BUCH.- HAM.) WALL. SEED EXTRACT

Inflammation is a chemical-mediated defense mechanism of body. Inflammatory process is also associated with development of various diseases like rheumatoid arthritis, psoriasis, atherosclerosis, and diabetes. Diabetes mellitus is a most common and life-threatening health problem in today’s date. Several marketed anti-diabetic drugs are characterized with side effects. Hence there is a need to se...

S. Saha * and E. V. S. Subrahmanyam

Department of Pharmacognosy, NGSM Institute of Pharmaceutical Sciences, Nitte (Deemed to be University), Mangaluru, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.12(7).3756-68

3756-3768

1866

1025

20.

IN-VITRO ALPHA-AMYLASE AND ALPHA-GLUCOSIDASE INHIBITORY ACTIVITIES OF POLYHERBAL FORMULATION

Diabetes mellitus is a chronic disease identified as hyperglycemia that occurs either when the pancreas does not produce enough insulin or when the body cannot metabolize its insulin. Insulin is a hormone that regulates blood sugar levels. Hyperglycemia, or raised blood sugar, is a common effect of uncontrolled diabetes and, over time, leads to serious damage to many of the body's systems. Alpha-a...

Asma Fathima, Anusha Dev and Praneetha Pallerla *

Sarojini Naidu Vanita Pharmacy Maha Vidyalaya, Osmania University Secunderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.13(7).2738-43

2738-2743

1865

975

11.

EVALUATION OF IN-VITRO ANTIFUNGAL POTENTIALITIES AND GC/MS SPECTROSCOPIC APPROACH OF CLEISTANTHUS COLLINUS (ROXB.) BENTH. EX. HOOK. F.

India is the home to the familiar plant Cleistanthus collinus (Roxb.) Benth. ex Hook. F (Euphorbiaceae) has great ethnomedicinal and therapeutic applications. The present study was designed to assess the phytochemical profile and investigate the antifungal effectiveness of leaf, bark and fruit extracts by using the agar well diffusion method. All crude extracts from leaf, bark, fruit and fractions...

Prathamanjali Satapathy, Vijaya Taratte * and Y. T. Rajesh Babu

Sri Venkateswara University College of Sciences, Sri Venkateswara University, Tirupati, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.14(10).4778-87

4778-4787

1865

1217

5.

HISTORICAL PERSPECTIVE OF LEAD POISONING AND THERAPEUTIC APPROACH OF GARLIC (ALLIUM SATIVUM) AGAINST VARIOUS HUMAN ALIMENTS

Lead comes in a category of toxic heavy metal which acts as a pollutant when present in high concentration in the environment and cause severe effects on the human body. Due to its continuous use its level increases and serves as a serious threat for the society.  Lungs and skin are the first organs which get affected by Lead toxicity. Lungs are the most important and sensitive part of human ther...

Veena Sharma * and Surabhi Gupta

Department of Bioscience and Biotechnology, Banasthali Vidyapith, Tonk, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.14(12).5595-05

5595-5605

1865

1988

3.

A WAY OF COMBATING ANTIMICROBIAL RESISTANCE THROUGH QUORUM SENSING

Quorum sensing is a peculiar mechanism of microbial communication through the induction of various signalling autoinducer molecules having several gene expression regulatory activities of different virulence factors that control microbial. This enables a systematic path of inhibiting microbial growth and its infection production efficacy by indirectly regulating the Quorum sensing activity of the ...

Shabnam Thakur *, Rupali Sharma and Rakesh Yadav

Amity Institute of Pharmacy, Amity University Haryana, Manesar, Gurgaon, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.13(10).3833-40

3833-3840

1864

892

48.

A CASE REPORT ON ANOREXIA NERVOSA

Anorexia nervosa (AN) is a life-threatening condition with the highest mortality rate of all psychiatric disorders. The core physiological features of ANare the extreme overvaluation of shape and weight. Severe AN causes cardiovascular complications and majorly refeeding syndrome. The prominent features of refeeding syndrome include severe hypo-phosphatemia, hypokalemia and hypomagnesia, and other...

Beny Margrat, Shravan Jayachandran, A. Priya and K. Arun Chander *

Department of Clinical Pharmacology, Apollo Children’s Hospital, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.13(10).4235-38

4235-4238

1863

1441

9.

A REVIEW OF HERBAL PLANTS USED IN THE TREATMENT OF RHEUMATOID ARTHRITIS

An inflammatory disorder with an uncertain cause, rheumatoid arthritis (RA), is primarily distinguished by progressive cartilage loss resulting in persistent polyarthritis and joint deformity. Studies indicate that pannus development, which harms the cartilage and the bone, is caused by synoviocyte cellular growth, albeit the exact pathophysiology of the condition has not yet been determined. Rece...

Hira Das *, Debgopal Ganguly, Sayan Hazra, Soumyadip Roy, Subhadip Barui and Sumit Mitra

Seacom Skills University, Kendradangal, Birbhum, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.14(7).3288-95

3288-3295

1863

1149

49.

COMPARISON OF ANTIOXIDANT POTENTIAL OF FRESH AND MARKETED SAMPLES OF MEDICINAL PLANT- ECLIPTA ALBA

The present study aimed at comparing the antioxidant potential of three different samples of Eclipta alba-fresh plant, marketed leaf powder (packaged in sealed containers), and marketed whole plant (sold in open bags). The presence of alkaloids, saponins, triterpenes, terpenoids, tannins, steroids, flavonoids, glycosides was confirmed in all three samples. Fresh plant samples showed a higher antio...

S. Sharma, G. Nandi, A. Chourasia, V. Kaushik, J. Bhatia, S. Waikhom, R. Meena and R. Sisodia *

Department of Botany, Maitreyi College, University of Delhi, Chanakyapuri, New Delhi, India.

DOI: 10.13040/IJPSR.0975-8232.12(8).4476-84

4476-4484

1863

1262

56.

AN IN-SILICO APPROACH TO DRUG DESIGNING ON NOVEL TARGET FOR TUBERCULOSIS CAUSED BY MYCOBACTERIUM TUBERCULOSIS

Worldwide, Tuberculosis (TB) remains the most frequent and important infectious disease caused by Mycobacterium tuberculosis (Mtb). TB Structural Genomics Consortium (TBSGC) reported 79,144 deaths and 26.9 lakh cases in 2019 (WHO). Although tuberculosis is a curable disease, the chances of a cure become slim as the disease becomes multidrug-resistant, and the situation gets even worse as the disea...

K. R. Suriya and V. Sivakumaran *

Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.12(6).3475-80

3475-3480

1862

980

34.

IN -VIVO EVALUATION OF ABIES PINDROW AS AN ANTI-DIABETIC PLANT

Background: The present study was carried to evaluate the phytochemical, antioxidant, and anti-diabetic potential of Abies pindrow leaf extracts. Methods: The extracted leaf samples of Abies pindrow in methanolic and hydroalcoholic solutions were evaluated for phytochemical and antioxidant activities. In-vitro antioxidant activity of both test samples was calculated by DPPH radical scavenging capa...

Rumaisa Jan, Sabeeha Shafi *, Seema Akbar and Shafat Akbar

Department of Pharmaceutical Sciences, University of Kashmir, Srinagar, Jammu and Kashmir, India.

DOI: 10.13040/IJPSR.0975-8232.13(10).4122-36

4122-4136

1862

1030