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A REVIEW ON PLANT OPILIA CELTIDIFOLIA: AN ASSESSMENT OF ITS BOTANY, CONVENTIONAL UTILIZATION, PHYTOCHEMISTRY AND PHARMACOLOGY
The plant Opilia celtidifolia, often known as ironwood or Opilia, is indigenous to many parts of Africa. It has a long history of traditional use in African herbal medicine, and its purported therapeutic benefits have attracted interest. An overview of Opilia celtidifolia's cultivation, the portions used, and the identification of its chemical components are given in this abstract. The savannahs, ...
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DESIGN, GREENSYNTHESIS AND MOLECULAR DOCKING STUDIES OF A NOVEL 2,4,5- TRIPHENYL IMIDAZOLE DERIVATIVE
The design and synthesis of a novel 2,4,5- Triphenyl imidazole derivative has been achieved using a green chemistry approach. These compounds were synthesized by using a sustainable catalytic material and solvent free one-pot reaction where benzil, aromatic aldehydes, ammonium acetate and acid chloride were reacted under microwave irradiation. This method offers several advantages including simpli...
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COMBINED MIXTURE DESIGN-DOE AND ION PAIR REAGENT: A SYNERGISTIC MODEL FOR THE SEPARATION OF MULTIPLE AMINO ACIDS IN RP-HPLC
The aim of the present study is to apply the Design of Experiments (DoE) to develop an assay method for the separation of amino acids by RP-HPLC. The method used in this study is the DoE Combined- Randomized method. Design of Experiments allows interpreting the results with better outcomes and enhanced understanding process. Ion pair reagent- Octane 1 Sulphonic acid sodium salt monohydrate of 0.01...
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HEPATOPROTECTIVE EFFECTS OF POLYHERBAL FORMULATION AGAINST CARBON TETRACHLORIDE-INDUCED HEPATIC INJURY IN ALBINO RATS
Objective: To investigate the hepatoprotective activity of polyherbal formulation composed of extracts of Bauhinia variegata, Oxalis corniculata, and Pterocarpus marsupium. Methods: The hepato-protective activity of the formulation and extracts were assessed on the basis of histopathological changes in the liver and estimation of SGOT, SGPT, SALP, serum bilirubin of carbon tetrachloride-induced he...
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MEDICINAL PLANTS IN PARKINSON’S DISEASE TREATMENT: A BRIEF REVIEW OF THE RECENT DATA
Parkinson's disease (PD) is a common neurodegenerative disorder that affects approximately 2% of the population aged over 65. Dopamine precursor L-3,4-dihydroxyphenylalanine (L-DOPA) is the main treatment to provide symptomatic relief for Parkinson’s disease (PD). However, with long-term administration of L-DOPA, as many as 95% of patients develop several complications. Medicinal plants (MP) and...
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NEUROPROTECTIVE EFFECT OF MADHUCA LONGIFOLIA LEAF EXTRACT AGAINST COLCHICINE: AN EXPERIMENTAL STUDY ON COGNITIVE DYSFUNCTION AND BIOCHEMICAL ALTERATIONS IN MICE
The goal of the research was to explain as a cognition enhancer the traditional claim of Madhuca longifolia (Sapotaceae) leaves. Dementia was activated by intracerebrovascular colchicine administration for 28 days. Madhuca longifolia leaves ethanolic extract was evaluated in mice for cognition-enhancing activity in colchicine-induced dementia using elevated plus maze (EPM), actophotometer, and bio...
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EFFECT OF SUGARCANE BAGASSE AS A SOURCE OF CARBON FOR ɑ-AMYLASE ENZYME AND ANTIBACTERIAL COMPOUND PRODUCING DIFFERENT TYPES OF WILD FILAMENTOUS FUNGI
The present investigation screening and characterization of α-amylase and antimicrobial compound producing filamentous fungi is used for extensive commercial applications in various sectors and is highly demanded in the Biotech industry. The results reveal that out of the carbon substrates alone, sugarcane bagasse with a combination of Tween-80 was found to yield maximum α-amylase (151.76 IU) un...
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COMPARATIVE ANALYSIS ON STRESS LEVEL AMONG THE MEDICAL AND ENGINEERING STUDENTS IN CHENNAI CITY, TAMILNADU-A CROSS-SECTIONAL STUDY
Background: Stress is an important factor determining the mental health of the individual. During this pandemic, a student's life has had a questionable influence in academics since an online platform was created to educate them. This study was done to assess the stress level among medical and engineering students. Materials and Methods: A cross-sectional study was conducted to assess the stress l...
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ANTIOXIDANT EFFICACY OF GARLIC DERIVED ALLICIN ON CULTURED BREAST CANCER CELL LINES
The present study aims at analyzing the efficiency of allicin, agarlic derived phytochemical or neutraceutical in elevating the activities of various enzymic antioxidants on its treatment to cultured breast cancer cell lines. In the experimental work, cultured breast cancer cell lines were treated with different doses of allicin, and through standardized protocols, the cell lines were assayed for ...
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ANTIDIABETIC EFFECT OF MIXTURE OF CYATHEA NILGIRIENSIS (HOLTTUM) AND PTEROCARPUS MARSUPIUM ROXB. IN STREPTOZOTOCIN INDUCED DIABETIC RAT MODEL
Diabetes mellitus is a metabolic disorder of the endocrine system and becoming a serious threat to mankind's health in all parts of the world. Herbal remedies are considered convenient for management of diabetes due to their traditional acceptability, availability, and less side effects than oral hypoglycaemic agents. Thus, the present study aims to test the toxic and antidiabetic effect of a trad...
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