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IN-VITRO ALPHA-AMYLASE AND ALPHA-GLUCOSIDASE INHIBITORY ACTIVITIES OF POLYHERBAL FORMULATION
Diabetes mellitus is a chronic disease identified as hyperglycemia that occurs either when the pancreas does not produce enough insulin or when the body cannot metabolize its insulin. Insulin is a hormone that regulates blood sugar levels. Hyperglycemia, or raised blood sugar, is a common effect of uncontrolled diabetes and, over time, leads to serious damage to many of the body's systems. Alpha-a...
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AN EXTENSIVE REVIEW ON EFFECTS OF PSYCHOBIOTIC BASED TREATMENTS IN AUTISTIC SPECTRUM OF DISORDER AND APPLICABILITY OF ZEBRAFISH AS A ROBUST MODEL FOR STUDYING ASD
Autism spectrum disorders (ASDs) refer to the group of neuropsychiatric disorders that alter neurodevelopment and mental function and are characterised by an extensive range of symptoms, including hyper-or hyposensitivity, repetitive behaviours, and impairments in social and academic functioning. Untangling the causation of ASD has been complicated, in part because distinct genetic abnormalities ...
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SCIENTIFIC APPRAISAL OF ROGHAN AHMAR JADEED (UNANI PHARMACOEPIAL OIL) IN THE MANAGEMENT OF PAIN RELATED TO MUSCULOSKELETAL DISORDERS: A REVIEW
Unani Medicine is the ancient system of medicine that deals with prophylactic and therapeutic management of various acute and chronic illnesses. Ilaj bilGhiza, Ilaj bit Tadbeer, Ilaj bid dawa and Ilaj bil yad are the essential modes of treatment in Unani Medicine. A broad term Waja’al-Mafāsil covers entire Musculoskeletal disorders (MSDs) like inflammatory, non-inflammatory, infectious, metabol...
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PERCHLORATE: HEALTH EFFECTS AND TECHNOLOGIES FOR ITS REMOVAL FROM WATER RESOURCES
Perchlorate has been found in drinking water and surface waters in the United States of America, Canada, and India. It is primarily associated with the release of perchlorate from defense and military operations where rocket and satellite operation production takes place. Natural sources of perchlorate contain certain fertilizers and potash ores. Although it is a strong oxidant, perchlorate is ver...
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DOCKING STUDY OF FLT3 RECEPTOR WITH TYROSINE KINASE FOR LEUKEMIA DISEASE
Leukemia is a disease of cancer that affects blood-forming tissues i.e., bone marrow and lymph nodes, which is associated with uncontrolled growth of WBCs. These cells are unable to fight against infection and weaken the ability of bone marrow to make RBCs and platelets. When leukemic cells overproduce, they interfere in circulatory cells' functioning, i.e., RBCs and platelets. Along this, leukemi...
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CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF NATURAL PLANT EXTRACT & NANO LOADED CHITOSAN/POLYVINYL ALCOHOL BASED COMPOSITE FILMS
We are creating composite films made of chitosan and polyvinyl alcohol that are filled with neem plant extract and NiO nanoparticles. The solution casting technique is used to produce chitosan-polyvinyl alcohol films. When chitosan was combined with polyvinyl alcohol, the water absorption of the film increased, and glutaraldehyde (0.5 ml) became used as the crosslinking agent. The compatibility of...
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ANTIMICROBIAL AND ANTI-INFLAMMATORY POTENTIAL OF THE LEAF EXTRACTS, COLUMN FRACTIONS AND COMPOUNDS OF THE MEDICINAL PLANT JASMINUM FLEXILE VAHL
The medicinal plant Jasminum flexile is reported in traditional medicine as an antidiabetic and anti-inflammatory agent. There is no scientific report on the antibacterial and anti-inflammatory activity of extracts of Jasminum flexile. This study investigated the antibacterial and anti-inflammatory potential of the hydroethanol extract of leaves of Jasminum flexile, its column fractions and consti...
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HISTOPATHOLOGICAL PROTOCOL TO FIND OUT THE MODE OF ACTION OF FUNGUS BEAUVERIA BASSIANA (BALSAMO) PREPARATION ON MIDGUT OF FOURTH IN STAR LARVAE OF ANOPHELES STEPHENSI (L.)
The effect of many plant extracts and microbial biopesticides on insects' different developmental stages and physiology have been widely studied from time to time, but the effect of microbial biopesticides on the mosquito tissues, especially mid gut tissues, is very few. Since the malaria vector is one of the most important inclusions in human health and mosquito-borne diseases represent a great h...
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OPTIMIZATION AND EVALUATION OF ANTIMICROBIAL COMPOUNDS PRODUCED BY STREPTOMYCES RUBRUS VLK-24
Optimizing the cultural conditions to enhance bioactive metabolite production by Streptomyces rubrus VLK-24 isolated from mangrove sediments as well as characterizing these compounds, has been taken up in this study. The culture broth inoculated in Yeast extract, Malt extract, and Dextrose broth and extracted with ethyl acetate exhibited high antimicrobial activity against test microorganisms, inc...
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A REVIEW OF THE MUTUALISTIC RELATIONSHIP OF ENDOPHYTIC FUNGI FOR THE PRODUCTION OF BIOACTIVE METABOLITES
Endophytes constitute a remarkably multifarious group of microorganisms ubiquitous in plants and maintain an imperceptible association with their hosts for at least a part of their life cycle. Their enormous biological diversity, coupled with their capability to biosynthesize bioactive secondary metabolites, has provided the impetus for a number of investigations on endophytes. There is a need to ...
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