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EVALUATION OF ANTI-ANXIETY ACTIVITY OF ACHYRANTHES AASPERA LEAVES
Anxiety is one of the main psychiatric disorders worldwide. Furthermore, it is difficult to find out the patients suffering from various kinds of anxiety diseases. Numerous herbal plants have been utilized to treat the anxiety disease in traditional medical systems for thousands of years because of their safety, efficacy, and effectiveness. The present study was designed to evaluate the anti-anxie...
1885
1031
MICELLAR LIQUID CHROMATOGRAPHY, A GREEN TECHNIQUE FOR ANALYSIS OF DRUG FORMULATIONS; A REVIEW
The most commonly used analytical method in drug research is reversed-phase high-performance liquid chromatography (RP-HPLC). RP-HPLC methods also use huge quantities of solvents and generate by-products that must be disposed of, posing environmental and operator health worries. Micellar Liquid Chromatography (MLC) is a green chromatographic process for pharmaceutical analysis in which surfactants...
1885
1152
ANALYSIS OF PHYTOCHEMICAL CONSTITUENTS, ANTI-MICROBIAL ACTIVITY AND MOLECULAR CHARACTERIZATION OF MEDICINAL WEED SONCHUS OLERACEUS L. USING RAPD MARKER
In present study, Himalayan weed Sonchus oleraceus extracts are screened for the occurrence of bioactive compounds, anti-microbial activity, and its molecular characterization using RAPD. The agar well diffusion method was used to detect anti-microbial activity of aqueous, methanol, chloroform and ethyl acetate extracts of S. oleraceus. The anti-microbial activity of different extract was checked ...
1884
916
NOVEL IN-SITU GEL TO PROVIDE SUSTAIN RELEASE DRUG DELIVERY FOR OCULAR FUNGAL KERATITIS
Ocular deliveries possess a challenging pharmaceutical approach due to poor absorption index through the corneal appendages and washing away of the drug through tears and lachrymal secretion. The ocular appendages lead to provide lesser bioavailability of conventional dosage forms; hence, frequent dosing is advised to get the optimum effect of the medicine. Therefore, in-situ gel offers a promisin...
1884
1143
ISOLATION OF PHYTOCONSTITUENTS AND EVALUATION OF JUSTICIA GENDARUSSA LEAF EXTRACTS FOR ANTI PARKINSONIAN ACTIVITY
The present study investigates the anti-parkinsonian activity of various extracts of Justicia gendarussa (JG) leaves in MPTP-induced neurotoxicity mice. Parkinson’s disease (PD) is a neurodegenerative syndrome belongs to a group of motor symptoms disorders. In PD, brain cells degenerated in some parts of the brain which produce dopamine. JG herb is widely distributed in tropical regions of the w...
1884
1058
DEVELOPMENT AND VALIDATION OF STABILITY INDICATING UPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF NETUPITANT AND PALONOSETRON IN CAPSULE
A simple, accurate, and precise stability-indicating method was developed for the simultaneous estimation of the Netupitant (NTPT) and Palonosetron (PLSN) in a capsule by UPLC. Chromatographic elution was processed through an HSS C18 (100 × 2.1 mm, 1.8m) reverse phase column, and the mobile phase composition of 0.01N KH2PO4 buffer (4.0 pH) and acetonitrile in the ratio of 55:45 was pumped through...
1883
1268
EVALUATION OF ERYTHROPOIETIN AS NEUROPROTECTANT IN ALCOHOL-INDUCED PERIPHERAL NEUROPATHY IN RATS
Alcoholic peripheral neuropathy is a potentially incapacitating complication of long-term excessive consumption of alcohol characterized by pain and dysesthesias, primarily in the lower extremities. The neurological effects of ethanol consumption are complex, encompassing both the central and peripheral nervous systems. It breaks into acetaldehyde which impairs and destroys the majority of neurona...
1883
933
DESIGN AND DEVELOPMENT OF MODIFIED RELEASE TABLET BY MIXED SOLVENCY ASSISTED SOLID DISPERSION OF VALSARTAN
In the present investigation, newly developed solid dispersion technology that precludes the use of organic solvent and decreases the individual concentration of hydrotropic agents, simultaneously decreasing their toxic potential, was employed for preparing dispersions of valsartan. Valsartan is a pro-drug which has poor bioavailability because of poor solubility as it belongs to BCS class II. Stu...
1883
1002
GREEN SYNTHESIZED GOLD NANOPARTICLE: A NOVEL APPROACH TOWARDS BIOMEDICAL AND PHARMACEUTICAL APPLICATIONS
Green synthesized gold nanoparticle is one of the most promising drug delivery approaches with biocompatibility and biodiversity. Various plant sources such as Aegle marmelos, Eugenia jambolana, Soursop, Persea Americana, Terminalia chebula, Aloe arborescens, Musa paradisiacal, Alternanthera philoxeroides, Cissus quadrangularis, Sterculia acuminate, Garciniaindica choissy, Eucalyptus globulus, Ros...
1881
994
REVIEW ON SCOPE AND APPLICATION OF POSTBIOTICS IN FOOD PRESERVATION
Food safety is at risk from several variables, including physical, chemical, and biological risks. In this context, biological risks are of utmost significance. The bacteria among them are crucial in producing food deterioration and food-borne illnesses. Additionally, a novel strategy has been applied in recent years that relies on pro-biotic and post-biotic to inhibit the increase of pathogenic m...
1881
1074