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MALE INFERTILITY: A REVIEW ON SPERMATOZOA PROTEOMICS AND FERTILITY-ASSOCIATED BIOMARKERS IDENTIFICATION
Male infertility has remained a complex multi-factorial disease and needs advanced molecular studies. The development of effective diagnostic capabilities has resulted in the desire to create minimally invasive tests to help in the understanding of the etiology of male infertility. In recent times, research on human sperm proteomics has gained momentum and provides detailed information regarding s...
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INSIGHTS INTO THE ROLES OF ANTIOXIDANTS IN CITRUS FRUITS
Citrus fruits are known for their nutritiousness. Role of vitamins and minerals play a major role in citrus fruits during plant-pathogen interactions. These fruits are the supreme fruit crops which contain flavonoids and phenolic compounds. These molecules benefit individuals who are all consuming and play an important role in fruit ripening and development. Mainly these molecules act as antioxida...
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COLD-ACTIVE EXO-INULINASE ENZYME: ISOLATION AND SCREENING OF ENDOPHYTIC MICROBES FROM FRUITS
Microbial inulinases have a great potential for industrial use in the production of fructose from inulin. Optimization of the growth parameters of the microbes is essential to obtain inulinase in sufficient quantity. The present work aims to obtain inulinase from different fruits of endophytic bacteria and optimize its growth parameters. In a total of 22 isolates and among them, each one isolates ...
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SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL STUDIES OF RUTHENIUM (II) COMPLEXES OF SUBSTITUTED 2-{4, 5-BIS[(E)-2-PHENYLETHENYL]-1H-IMIDAZOL-2-YL}-1H-BENZIMIDAZOLE
Ruthenium(II) complexes of the type [Ru(bpy) 2(L)](PF6)2, where L= 2-{4,5-bis[(E)-2-phenylethenyl]-1H-imidazol-2-yl}-1H-benzimidazole (1), 2-{4,5-bis[(E)-2-(4-chlorophenyl)ethenyl]-1H-imidazol-2-yl}-1H-benzimi-dazole (2), 2-{4,5-bis [(E)-2-(4-fluorophenyl) ethenyl]-1H-imidazol-2-yl} -1H-benzimidazole (3), 2-{4 ,5-bis[(E)-2- (4-methylphenyl) ethenyl] -1H-imidazol-2-yl }-1H-benzimidazole (4), 2-{4, ...
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FORMULATION, OPTIMIZATION AND EVALUATION OF GLIMEPIRIDE TRANSFERO-SOMAL GEL FOR ANTIDIABETIC ACTIVITY IN RATS
Transferosomes are a special liposome type consisting of phosphatidylcholine and an edge activator. Glimepiride is a second-generation sulphonylurea exerting its effects in patients with type II Diabetes. Glimepiride is hydrophobic in nature possess less solubility and permeability. The study aims to formulate, optimize and evaluate Glimepiride Transferosomal gel for antidiabetic activity in Rats....
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IN-VITRO ANTIBACTERIAL AND ANTIOXIDANT EVALUATION AND QUALITY ASSESSMENT OF POLYHERBAL DRUG: TRIPHALA CHURNA
Triphala churna is a poly-herbal preparation that has anantiquity of usage in the conventional Indian medical system. It is rich in antioxidants and has excellent therapeutic efficacy. According to ayurveda, the churna is made using the raw ingredients Amalaki (Indian Gooseberry), Haritaki (Indian Hog Plum), and Bibhitaki (Vibheetaki) in an equal proportion (1:1:1). The present investigation purpo...
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BRIEF OVERVIEW STUDIES ON ENDOCRINE DISRUPTORS POLYCYCLIC AROMATIC HYDROCARBONS WITH SPECIAL REFERENCE TO NEWSPAPER INK
Now a day’s food materials are packaged and wrapped in paper that is the dangerous practice of wrapping, covering or processing foods with newspaper and printed recycled paper materials remains commonplace worldwide, as seen in the plethora of photographs in advertisements online or in magazines showing newspaper wrapped foods. The health hazard of ink contamination to foods and long-term contac...
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PREPARATION, CHARACTERIZATION AND IN-VITRO EVALUATION OF BERBERINE LOADED NANOEMULSION FOR ENHANCED ANTIMICROBIAL EFFICACY
Aim: The current research aimed to formulate and evaluate herbal nanoemulsion of poorly soluble Berberine hydrochloride, which can provide a realistic alternative for treating microbial infections. Materials and Methods: The drug was characterized using various analytical techniques such as Ultraviolet Spectroscopy, Fourier transform infrared spectroscopy, and Differential Scanning Calorimetry s...
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IN-VITRO ANTIOXIDANT AND ANTIDIABETIC ACTIVITY OF CUMINIC ACID
Diabetes mellitus is a metabolic disorder caused due to lack of insulin and/or its insufficiency. It is ranked ninth among the leading causes of death globally. As Oral hypoglycemic agent usage causes one or more side effects, phytochemicals can be used as alternative herbal medicine to treat diabetes mellitus with little or no side effects. In the current study, Cuminic acid was evaluated for its...
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EVALUATING THE PARAMETERS FOR SELECTING THE BEST METHOD FOR THE PRE-PARATION OF NANOCRYSTALS BY USING FUZZY ANALYTIC HIERARCHY PROCESS
The aim of this paper is to select the best method for the preparation of nanocrystals by using the fuzzy analytic hierarchy process (Fuzzy-AHP) methodology. The commonly used methods for the preparation of nanocrystals are Hydrosol, sonoprecipitation, spray freezing into liquid, and Nanomorph®. There are several parameters to take into consideration for the selection of the best method like oper...
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