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EFFECT OF CHROMIUM ON IN-VITRO GROWTH AND ANTIOXIDANT POTENTIAL OF DIANTHUS CARYOPHYLLUS L.
Catalase, guaiacol peroxidase and polyphenol oxidase are antioxidant enzymes that are important in the metabolism of reactive oxygen species and can be induced by environmental stresses including chromium (Cr), heavy metal toxic to living organisms. In-vitro regenerated shoots of carnation (Dianthus caryophyllus L.) were exposed to K2Cr2O7, and the activities of these antioxidant enzymes were anal...
1930
1112
DESIGN AND EVALUATION OF MUCOADHESIVE BUCCAL PATCHES OF SALBUTAMOL SULPHATE BY USING HUPU GUM AND LANNEA GUM
The purpose of the present investigation is to evaluate the applicability of hupu gum and lannea gum in the design of buccoadhesive patches for extended-release over a period of 6 hours, using Salbutamol sulphate as a model drug. The efficiency of these polymers was compared with already established synthetic polymer PEO coagulant. The patches were prepared by using the solvent casting method in w...
1929
1033
BIOSYNTHESIS, PURIFICATION, AND CHARACTERIZATION OF MONK FRUIT SWEETENER, SIAMENOSIDE I
An efficient and high yield synthesis of Siamenoside I (1), from Mogroside V (2) is reported. Siamenoside I (1) was obtained by enzymatic hydrolysis of Mogroside V (2). Bioconversion process involved enzymatic modification followed by separation and purification processes, including reversed-phase chromatography. The final product, a dried white powder, undergoes several stages of concentration, r...
1929
1845
TELMISARTAN NIOSOMES DESIGN, DEVELOPMENT AND CHARACTERIZATION
Telmisartan has a strong, nonpeptide antagonist with long-acting angiotensin II type-1 (AT 1) receptor to treat essential hypertension. It is classified as a BCS class II medication, meaning it has poor solubility and high permeability. Because of their capacity to minimise toxicity and change bioavailability, niosomes are becoming increasingly essential in medication delivery. Telmisartan-loaded...
1928
1053
ONGOING ADVANCEMENT IN THE COMPREHENSION OF MITOCHONDRIAL PRO-GRESSION WITH AN EXCEPTIONAL SPOTLIGHT ON ITS RELATIONSHIP WITH CANCER AND POSSIBLE THERAPEUTIC STRATEGY
Cancer is one of the main reasons of death around the world and the quantity of new incidents keeps on rising. Despite ongoing advances in conclusion and remedial systems, many malignancy-related passes happen, demonstrating the requirement for better treatments and symptomatic methodologies. Mitochondrial morphology is dependent on continuous fusion and fission strategies that are essential for m...
1928
1102
STUDIES ON IN-VITRO ANTICANCER AND ANTIOXIDANT PROPERTIES FROM MARINE BACTERIAL PIGMENT ISOLATED FROM THE COASTAL AREA OF MARAKANAM (TN)
Marine bacteria have the potentiality to produce diverse bioactive molecules such as pigment. Therefore, it needs to exploit and identifying a novel type of pigment from marine bacteria for Industrial applications. This study aimed to investigate the marine bacterial pigment against antioxidant and anti-cancer properties; the marine bacteria producing pigment were isolated from water samples colle...
1927
1177
QUANTITATIVE AND QUALITATIVE PHYTOCHEMICAL ANALYSIS IN BARK OF NOTHOPEGIA RACEMOSA (DALZ.) RAMAM. COLLECTED FROM GADIKALLU, SHIMOGGA, KARNATAKA
Plants are a source of bioactive compounds produced by different parts of the plant, maybe bark, leaves, flowers, roots, fruits, and seeds, during metabolic activities. These secondary metabolites may have protective and disease preventive properties, hence used by Traditional practioner to treat various ailments. Most plants of the Western Ghats of India remain unknown, poorly understood or unest...
1926
1284
AN EXPERIMENTAL STUDY TO ASSESS THE MEMORY-ENHANCING PROPERTY OF PITAVASTATIN AND GEMFIBROZIL IN MICE USING THE MORRIS-WATER MAZE MODEL. EVIDENCE TO CATEGORIZE THEM AS SMART DRUGS
Introduction: Discovery of smart drugs is part of advancing the science of molecular and biochemical mechanisms of memory. Smart drugs are not just memory boosters; they also act as memory enhancers that help quick decision-making. Pitavastatin and gemfibrozil both cause lipid-lowering effects by different mechanisms of action. A few studies show they can act on CREB (c-AMP response elemental bind...
1926
759
CORRELATION OF ANTIOXIDANT, ANTIBACTERIAL AND PHYTOCHEMICALS OF LEAVES AND ROOTS EXTRACTS OF CLERODENDRUM INFORTUNATUM
The leaves and roots extracts of Clerodendrum infortunatum was evaluated for its potential antioxidant and antibacterial properties. The correlation studies with phytochemicals were performed, which has not been widely reported yet. Clerodendrum infortunatum leaves and roots were screened for the presence of phytochemicals and were found positive for carbohydrates, saponins, alkaloids, tannins, ph...
1925
1217
THE CURRENT REGISTRATION REGULATIONS OF COSMETIC PRODUCTS IN “BRICS” COUNTRIES
Cosmetic products are produced by the most inventive and technically driven methods to reach more consumers in the developing world. Cosmetic products are also regulated, similar to pharmaceutical products. BRICS countries are emerging markets with a partial regulatory system similar to well-regulated countries. BRICS countries have a registration or notification process for cosmetics based on the...
1925
1110