Most Popular
STUDIES ON ANTIMICROBIAL ACTIVITY OF HIBISCUS SPECIES OF KARNATAKA AGAINST CLINICAL ISOLATES
Antimicrobial activity of the various species of Hibiscus like Hibiscus sabdariff, Hibiscus rosa-sinensis, Hibiscus trionum, Hibiscus cannabinus, Hibiscus mutabilis against various pathogens like Staphylococcus aureus, E. coli, Bacillus subtilis, Streptococcus species, Salmonella typhimurium, Klebsiella pneumonia, Pseudomonas aeruginosa, Serratia marcescens, were studied with the help of agar well...
1993
1029
EFFECT OF STARCH ISOLATION METHODS ON CHEMICAL, FUNCTIONAL AND STRUCTURAL PROPERTIES OF PEARL MILLET STARCH (PENNISETUM TYPHOIDIUM)
The study was carried out to determine the chemical, functional, and structural properties of starch that was isolated by various methods from pearl millet (Pennisetum Typhoidium). Isolation methods of starch with different chemicals influenced starch properties. Pearl millet starch was isolated by Sodium azide (alkaline) (T1), Sodium metabisulfite & lactic acid (T2) (neutral), and Mercuric ch...
1993
1145
ANTIPSORIATIC ACTIVITY OF GENISTEIN: A REVIEW
Psoriasis is a chronic inflammatory skin disease characterized by red, scaly and raised patches, and it has affected nearly 2-3% of the population worldwide. This skin disorder occurs when the immune system sends faulty signals that result in the speeding up of the skin cell cycle. Psoriasis is histologically characterized by marked hyperproliferation of keratinocytes, neutrophils, and a dense inf...
1992
1008
AN UPDATED REVIEW ON GLOBAL PHARMACEUTICAL FORMULATION DEVELOPMENTS AND FUTURE POTENTIAL OF NON-INVASIVE TRANSDERMAL DRUG DELIVERY SYSTEM
Background: Over the last several years, there has been much research into the development and modification of new pharmaceutical substances. We have also been able to attain the newest in transdermal drug delivery system treatment with existing pharmaceuticals. We have successfully implemented numerous drug regimens with transdermal delivery systems as one of the most significant developments, of...
1992
1174
SEXUAL DIMORPHISM OF FEMUR IN THE POPULATION OF ODISHA: AN ANTHROPOMETRIC OBSERVATIONAL STUDY
Introduction: Femur is the key bone among the skeletal remains to determine sex for anatomists, anthropologists, and forensic experts. In the present study, we considered most of the parameters to determine sex from the femur. Methods: We studied eighty-four undamaged, intact femora of unknown sex. The present study were carried out in S. C. B. Medical College Cuttack from December 2019 to April 2...
1991
1134
IN-SILICO MOLECULAR DOCKING STUDIES, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL FURAN-AZETIDINONE HYBRIDS AS POTENTIAL ANTI-CANCER AGENTS
Furan and Azetidinone have been reported to possess various therapeutic activities, including anti-microbial and anti-cancer activity. Increasing drug resistance and high toxicity to the existing drugs have dictated the need to develop novel, effective agents with different scaffolds. With the perspective of identifying novel anti-cancer molecules, an approach was made to hybridize the different h...
1991
1282
IDENTIFYING TUBULIN AS A NEW TARGET OF A DIHYDROPYRIDINE DERIVATIVE, AMLODIPINE BESYLATE
The quest for new antimitotic drugs is an ongoing process where microtubules act as an attractive target for anti-cancer drugs. In this work, we report on the anti-cancer activity of Amlodipine besylate (AB), a salt derivative of the dihydropyridine groupdrug Amlodipine, a long-acting third-generation calcium channel blocker. Cytotoxicity assay revealed that AB demonstrated cytotoxic effects again...
1990
933
STRUCTURAL TRANSFORMATION OF LUPEOL AND EVALUATION THEIR IN-VITRO ANTIOXIDANT ACTIVITY
Lupeol (I) is a naturally occurring triterpene that has been isolated from the stem bark of Crataeva nurvala in appreciable amount. Due to the presence of a single hydroxyl group and a large, apolar skeleton, lupeol acts as an amphiphile. The two possible sites for chemical modification present in lupeol are ring-A and isopropenyl side chain. We modified it in three naturally occurring analogous d...
1990
1140
ENHANCING THE EXTRACTION OF POLYPHENOLS FROM ACACIA LEUCOPHLOEA BARK BY MICROWAVE-ASSISTED ENZYMATIC EXTRACTION METHOD AND IN-VITRO STUDY OF ITS ANTIOXIDANT AND ANTIBACTERIAL ACTIVITY
This study aims to identify the suitable method for extraction of polyphenols from Acacia leucophloea bark using enzymes and to optimize the processing condition for extraction using Response Surface Methodology. A microwave-assisted enzymatic extraction (MAEE) method was developed and optimized to augment the polyphenol yield. The optimal extraction conditions were as follows: the amount of cellu...
1990
1071
CORRELATION OF ANTIOXIDANT, ANTIBACTERIAL AND PHYTOCHEMICALS OF LEAVES AND ROOTS EXTRACTS OF CLERODENDRUM INFORTUNATUM
The leaves and roots extracts of Clerodendrum infortunatum was evaluated for its potential antioxidant and antibacterial properties. The correlation studies with phytochemicals were performed, which has not been widely reported yet. Clerodendrum infortunatum leaves and roots were screened for the presence of phytochemicals and were found positive for carbohydrates, saponins, alkaloids, tannins, ph...
1989
1244