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HIGHLY BIOACTIVE ULTRA SMALL VANCOMYCIN DOPED SILVER NANOPARTICLES GROWN BY SOL-GEL METHOD
Highly bioactive ultra-small vancomycin doped silver nanoparticles were synthesized by the sol-gel method. The samples were characterized by UV, FR-IR, XRD, Photoluminescence, and TEM analysis. Continuous stirring helped in preparing ultra-small drug conjugate silver nanoparticles. Observation of weak (broadened peak) in XRD diffractograms indicates the formation of very small size drug conjugate ...
1949
1052
AMYOTROPHIC LATERAL SCLEROSIS: RAPIDLY ACCELERATING COMPLEX NEURO-DEGENERATIVE DISEASE
An amyotrophic lateral sclerosis is a group of progressive neurodegenerative disorders of motor neurons that leads to weakness, muscle atrophy, progressive paralysis, and respiratory insufficiency with a life anticipation of only three years after the onset of disease symptoms. It impairs the functions of both upper and lower motor neurons. The specific mechanism for the disease remains largely un...
1949
1025
STUDIES ON ANTIMICROBIAL ACTIVITY OF HIBISCUS SPECIES OF KARNATAKA AGAINST CLINICAL ISOLATES
Antimicrobial activity of the various species of Hibiscus like Hibiscus sabdariff, Hibiscus rosa-sinensis, Hibiscus trionum, Hibiscus cannabinus, Hibiscus mutabilis against various pathogens like Staphylococcus aureus, E. coli, Bacillus subtilis, Streptococcus species, Salmonella typhimurium, Klebsiella pneumonia, Pseudomonas aeruginosa, Serratia marcescens, were studied with the help of agar well...
1949
1011
FORMULATION AND IN-VITRO EVALUATION OF SOLID LIPID NANOPARTICLES CONTAINING NADOLOL
The solid lipid nanoparticles are sub-micron colloidal carriers (50-100 nm) that are composed of physiological lipid dispersed in water or in aqueous surfactant solution. Nadolol-loaded SLNs were prepared by modified high shear homogenization. It was observed that all formulations contain a good product yield. The highest drug content was found in formulation F5 98.37%. Entrapment efficiency for f...
1949
1099
REPLACEMENT OF ORGANIC SOLVENTS WITH ENVIRONMENTAL ECO-FRIENDLY SOLVENTS FOR RP-HPLC ANALYSIS
Background: Solvents are major part in chemical industry. Solvents have major impact on cost as well as safety and health issues. Many more organic solvents are considered toxic. Thus the concept of green chemistry is introduced which eliminate or reduce the use of hazardous solvents/chemicals from analytical process for the eco-friendly environment and health without any compromise in Analytical ...
1948
1238
UTILIZATION PATTERN OF ANTI-MICROBIAL DRUGS IN OPHTHALMOLOGY DEPARTMENT AT A TERTIARY CARE HOSPITAL
Ophthalmologists generally treat ocular infections by giving prophylactic anti-microbial therapy as they do not have data from culture analysis. The indiscriminate use of anti-microbials can lead to drug resistance, difficulty in treating infections, and increased chances of severe ocular damage. The purpose of this study was to analyze the utilization of anti-microbial drugs in the ophthalmology ...
1948
1024
AN UPDATED REVIEW ON GLOBAL PHARMACEUTICAL FORMULATION DEVELOPMENTS AND FUTURE POTENTIAL OF NON-INVASIVE TRANSDERMAL DRUG DELIVERY SYSTEM
Background: Over the last several years, there has been much research into the development and modification of new pharmaceutical substances. We have also been able to attain the newest in transdermal drug delivery system treatment with existing pharmaceuticals. We have successfully implemented numerous drug regimens with transdermal delivery systems as one of the most significant developments, of...
1947
1142
COVID-19 PANDEMIC-A FORTUNATE SCENARIO FOR PHARMACEUTICAL SCIENTISTS
Covid-2019: The pandemic that shook the entire world. There is no sarcasm if one says there will be a Pre and Post- COVID-19 world. Worldwide, millions of cases have been identified, and heaps have died. So many nations worldwide have issued a lockdown to stop the coronavirus's unfolding, which triggered giant financial fallout. Like each and every incident has two dimensions, Covid-19 possesses b...
1946
868
TREATMENT STRATEGIES FOR NEURODEGENERATIVE DISEASES THROUGH IMPORTANT MEDICINAL PLANTS USED IN UNANI MEDICINE
Neurodegenerative diseases (NDs) that are characterized by progressive loss of functioning and structure of neurons are of great burden to the individuals and the society. With several hypotheses, the existent cause still remains a mystery for various NDs in healthcare. Protein degradation, inflammation, oxidative stress, environmental factor, mitochondrial defects, abnormal protein accumulation i...
1946
1077
DESIGN AND EVALUATION OF ZERO-ORDER DRUG-RELEASING RIVASTIGMINE TRANSDERMAL SYSTEM
Rivastigmine is used for the treatment of mild to moderate dementia of the Alzheimer’s type. Transdermal delivery of Rivastigmine is preferable to improve gastrointestinal tolerability. A novel transdermal system with zero-order release kinetics was developed following a hybrid technique in a combination of the micro reservoir and adhesive dispersion system. The transdermal system was prepared b...
1946
1229