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A STUDY ON TERNARY MIXTURE OF PEPTIDE USING ULTRASONIC, IN-VITRO AND IN-SILICO PROCESSES
Penetrating biomolecules by ultrasonic techniques is an innovative and influential tool for characterizing their physicochemical properties. Peptides have been used as extensive applications in drug construction and as an ingredient in nutritional complements. An investigation based on the behavior of promulgation of ultrasonic waves in solids and the liquid system is now rather well recognized as...
1944
1113
ANTIAPOPTOTIC MECHANISM FOR THE IMPLEMENTATION OF THE HEPATOPROTECTIVE EFFECT OF PYRIMIDINE DERIVATIVES
The present study aimed to study the effect of the drug Xymedon and its conjugate with L-ascorbic acid exhibiting hepatoprotective activity on the apoptosis of rat liver cells against the background of the influence of hepatotoxic agent tetrachloromethane. Though the general effects of Xymedon and its conjugates with various biogenic acids have been studied, the molecular markers affected by the c...
1944
994
BIOACTIVE CHEMICAL CONSTITUENTS OF BLEPHARIS AND LEPIDAGATHIS (ACANTHACEAE) – A REVIEW
The herbal drugs derived from plant sources are used in traditional pharmacopeia and also act as precursor in lab to synthesize medicines at large scale. Acanthaceae is a large family comprising of various medicinally valuable species. In traditional use, the leaves of this family are commonly recognized to alleviate the poisonous bites of reptiles and insects and whole plants for the treatment of...
1944
1376
QUALITATIVE ANALYSIS OF PHYTOCHEMICAL CONSTITUENTS OF CERTAIN ETHNOMEDICINAL PLANTS IN BHADRAVATHI TALUK OF SHIVAMOGGA DISTRICT, KARNATAKA
Medicinal plants are an abundant source of bioactive compounds, which have been used for thousands of years against different diseases because plants have antibacterial, anti-inflammatory, and antifungal activities. All of the medicinal plants that may be found on earth today have specific therapeutic use and importance. Our research work is based on the qualitative phytochemical studies of extrac...
1943
926
COMPUTATIONAL APPROACH FOR DESIGNING AND DEVELOPMENT OF POTENT DRUG INHIBITOR FOR APP GENE IN ALZHEIMER’S DISEASE
Alzheimer’s disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills, reasoning, planning, language, and perception, and eventually even the ability to carry out the simplest tasks. Many scientists believe that Alzheimer's disease results from an increase in the production or accumulation of a specific protein (beta-amyloid protein) in the brain ...
1943
834
0
FERULIC ACID: A NATURAL ESSENTIAL COMPOUND HAVING POTENTIAL INDUSTRIAL AND MEDICINAL PROPERTIES
The ubiquitous compound 4-Hydroxy-3-methoxy cinnamic acid, also known as ferulic acid, constitute. A bioactive ingredient of many food that may offer a potential therapeutic effects useful in the treatment of cancer, diabetes, lung and cardiovascular disease. It is also effective against the disorders relative to oxidative stress, including certain neurodegenerative diseases. Ferulic acid is widel...
1943
1363
SCALE-UP OF EXTRACTION PROCESS FOR DILL SEED OIL
Concentrated preparations called extracts are made from raw materials by isolating specific components through specific methods. Essential oils, tinctures, liquid extracts, and dry extracts are among the different kinds of extracts. The type of input material, the solvent employed, the temperature, and the extraction time are all important variables. Efficiently isolating and condensing particular...
1942
1353
FORMULATION AND IN-VITRO EVALUATION OF SOLID LIPID NANOPARTICLES CONTAINING NADOLOL
The solid lipid nanoparticles are sub-micron colloidal carriers (50-100 nm) that are composed of physiological lipid dispersed in water or in aqueous surfactant solution. Nadolol-loaded SLNs were prepared by modified high shear homogenization. It was observed that all formulations contain a good product yield. The highest drug content was found in formulation F5 98.37%. Entrapment efficiency for f...
1941
1093
DESIGN AND EVALUATION OF ZERO-ORDER DRUG-RELEASING RIVASTIGMINE TRANSDERMAL SYSTEM
Rivastigmine is used for the treatment of mild to moderate dementia of the Alzheimer’s type. Transdermal delivery of Rivastigmine is preferable to improve gastrointestinal tolerability. A novel transdermal system with zero-order release kinetics was developed following a hybrid technique in a combination of the micro reservoir and adhesive dispersion system. The transdermal system was prepared b...
1941
1219
UTILIZATION PATTERN OF ANTI-MICROBIAL DRUGS IN OPHTHALMOLOGY DEPARTMENT AT A TERTIARY CARE HOSPITAL
Ophthalmologists generally treat ocular infections by giving prophylactic anti-microbial therapy as they do not have data from culture analysis. The indiscriminate use of anti-microbials can lead to drug resistance, difficulty in treating infections, and increased chances of severe ocular damage. The purpose of this study was to analyze the utilization of anti-microbial drugs in the ophthalmology ...
1939
1018