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APPLICATIONS OF ELECTROSPUN NANOFIBERS IN THE TREATMENT OF PERIODONTAL DISEASES
A periodontal disease is a group of pathological diseases, i.e., a widespread infectious disease that mainly causes tooth loss in 15% of adults worldwide. For the treatment of these periodontal diseases, localization of the drug is necessary i.e.; the drug has to be delivered to the periodontal pocket, which is the main area for the development of bacteria. So, researchers have made many attempts ...
1908
1175
FORMULATION AND EVALUATION OF pH TRIGGER NASAL IN-SITU GEL OF LEVOCETIRIZINE HYDROCHLORIDE FOR LOCALIZED TREATMENT OF ALLERGIC RHINITIS
Objective: This dissertation work aimed to prepare Levocetirizine HCL (LCH) nasal in-situ gel, a second-generation antihistamine, to improve its retention time, sustain release, enhance the bioavailability, and avoid first-pass metabolism. Process: The in-situ nasal gel was prepared to consume Carbopol as a gelling agent, Hypromellose (HPMC) as a thickening or thickness-imparting agent, and buffer...
1908
1117
RECENT ADVANCEMENTS IN THE FORMULATION AND EVALUATION OF MICROPARTICLES AND ITS APPLICATION
Introduction: The micro particles and development in the area of micro particles analysis are discussed in this article. Areas Covered: Micro particles are a unique drug carrier method that provides an effective therapeutic alternative to single-unit dose forms that are either traditional or rapid release. Micro particles are produced by filling them with firm gelatin or compressing them immediate...
1907
1222
IN VITRO ANTIOXIDANT AND IN VIVO IMMUNOMODULATORY STUDY OF LEMON PEEL EXTRACT (STORG-FA) AND ITS BIOAVAILABILITY ASSESSMENT
Background: Natural bioactive compounds of plant origin have attracted comprehensive attention due to their multiple biological effects, including antioxidant and immunomodulatory activities. However, scientific underpinnings of these health benefits are inadequate. Objective: Present investigation was undertaken to evaluate the bioavailability, antioxidant, and Immunomodulatory activity of the he...
1907
998
IN-VITRO AND IN-SILICO STUDIES ON SELECTED PHYTOCONSTITUENTS OF MITRAGYNA PARVIFOLIA (ROXB.) STEM BARK FOR ANTI-CANCER ACTIVITY
Cancer is a dreadful disease all over the world. The death rate had been increasing because of different types of cancers even though several drugs, treatment models and regimens are invented by scientists. Natural drugs have been showing remarkable results in the treatment of different cancers with less or no side effects. Advancements in screening methods using computer aided tools helping the r...
1906
1190
QBD APPROACH FOR THE DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF FORMOTEROL FUMARATE AND ACLIDINIUM BROMIDE IN PRESSURIZED METER DOSE INHALER
A Quality design approach to method development involves method goal identification, method scouting and evaluation, method selection, and risk assessment. The present study describes the risk-based HPLC method development and validation of Formoterol fumarate and Aclidinium bromide in a pharmaceutical dosage form. The chromatographic conditions were optimized with the Design Expert software 11.0 ...
1906
1021
FORMULATION AND EVALUATION OF HERBAL LIPSTICK USING NATURAL COLOUR EXTRACT FROM AMARANTHUS GANGETICUS LINN LEAF
Cosmetics have been in high demand since ancient times until today. Lipsticks are a type of cosmetic used to enhance their appearance and protect the lips. Generally, waxes, oils, emollients, pigments, and varieties of dye or colouring agents are used to prepare lipsticks. Synthetic colours and other ingredients are hazardous to the human skin and body. Substituting synthetic ingredients with natu...
1906
940
TASTE MASKING, DESIGN AND EVALUATION OF ORAL DISPERSIBLE TABLET OF ANTICHOLINESTERASE AGENT
This study aimed to determine for taste masking & design of Oro dispersible tablet of an anticholinesterase agent (Donepezil HCl) to achieve the patient compliance. Oral dispersible tablet prepared by compression method. The Anticholinergic activity assure by evaluation, drug dissolution, stability testing and standardize the oral dispersible tablet. On the basis of the preformulating and form...
1905
1213
MODERN SOLUTIONS FOR HERNIA REPAIR: A REVIEW OF MESH INNOVATIONS AND EMERGING SURGICAL TRENDS
Hernia repair is one of the most common surgeries, with recent advancements in mesh technology and surgical techniques significantly improving outcomes. Mesh implants are the standard for reinforcing abdominal walls, reducing recurrence rates compared to traditional sutures. However, complications like chronic pain, infection, and adhesions have driven innovations in mesh development. Modern synth...
1905
824
HISTOLOGICAL AND PHYTOCHEMICAL ANALYSIS OF FOUR ETHNOMEDICINAL PLANTS USED TO CURE SKIN DISEASES
Natural plant-derived compounds have been an essential resource in the evolution of drug discovery since the dawn of time. Using plants as a source of medicine is a century-long-standing tradition not merely in India but also in the entire world. North-East India is bestowed with incredible biological richness. The current research is focused on the histological and phytochemical analysis of four ...
1904
967