Most Popular
IN VITRO ANTIOXIDANT AND IN VIVO IMMUNOMODULATORY STUDY OF LEMON PEEL EXTRACT (STORG-FA) AND ITS BIOAVAILABILITY ASSESSMENT
Background: Natural bioactive compounds of plant origin have attracted comprehensive attention due to their multiple biological effects, including antioxidant and immunomodulatory activities. However, scientific underpinnings of these health benefits are inadequate. Objective: Present investigation was undertaken to evaluate the bioavailability, antioxidant, and Immunomodulatory activity of the he...
1952
1025
EVALUATION OF PHYTOCHEMICAL ANALYSIS OF CALLUS TISSUE FROM INTERNODE EXPLANTS OF TRADITIONAL MEDICINAL PLANTS OF JATROPHA GOSSYPIIFOLIA LINN.
Jatropha gossypiifolia Linn. (Euphorbiaceae) is an ornamental shrub extensively used in traditional medicine for various ailments. In view of its potential medicinal properties, an attempt has been undertaken to devise an efficient protocol for in-vitro propagation from the internodes explants of J. gossypiifolia for a rapid and large-scale production as well as to study the phytochemical composit...
1951
1232
ASSESSING THE ANTIOXIDANT ACTIVITIES OF METHANOLIC EXTRACT OF SARACA ASOCA LEAVES AND BARK
Chronic diseases such as cardiovascular, cancer, and respiratory diseases are being increased. Reactive oxygen species, free radicals, and oxidative stress play a major role in aggravating these diseases. Plants and plant-derived compounds have shown a greater potential in combating the detrimental effects of free radicals and other toxic agents. The current research work has been done on the leaf...
1951
1096
HISTOLOGICAL AND PHYTOCHEMICAL ANALYSIS OF FOUR ETHNOMEDICINAL PLANTS USED TO CURE SKIN DISEASES
Natural plant-derived compounds have been an essential resource in the evolution of drug discovery since the dawn of time. Using plants as a source of medicine is a century-long-standing tradition not merely in India but also in the entire world. North-East India is bestowed with incredible biological richness. The current research is focused on the histological and phytochemical analysis of four ...
1951
981
QBD APPROACH FOR THE DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF FORMOTEROL FUMARATE AND ACLIDINIUM BROMIDE IN PRESSURIZED METER DOSE INHALER
A Quality design approach to method development involves method goal identification, method scouting and evaluation, method selection, and risk assessment. The present study describes the risk-based HPLC method development and validation of Formoterol fumarate and Aclidinium bromide in a pharmaceutical dosage form. The chromatographic conditions were optimized with the Design Expert software 11.0 ...
1951
1040
RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF VIBEGRON IN PURE AND PHARMACEUTICAL DOSAGE FORM
An accurate, sensitive, precise, fast isocratic reverse phase HPLC technique has been developed and validated for the quantification of Vibegron in the pure and pharmaceutical dosage form. The best separation was achieved on a 250 mm x 4.6 mm ID., 5µ-particle size Inertsil®-Octadecyl-Silyl-3V-Reverse-Phase-C18-column with 0.05M Ammonium dihydrogen orthophosphate in water: acetonitrile (60:40...
1950
1435
EFFECTS OF TEMPERATURE AND TIME OF ROASTING ON THE PHYSICOCHEMICAL AND ANTIMICROBIAL CHARACTERISTICS OF CINNAMON BARK OIL
The purpose of the present study was to examine the influences of roasting and the effects of roasting temperature and duration on the chemical composition of cinnamon bark oil and to extend our knowledge concerning the changes in antioxidant activity, antimicrobial activity, physical properties such as colour, refractive index, density and contents of cinnamaldehyde and other components of cinnam...
1949
939
RADIOLOGICAL AND GENE-EXPERT PATTERN: IN RELATION WITH TREATMENT OUTCOME OF SENSITIVE AND RESISTANT TUBERCULOSIS
Even if there are so many diagnostic tests available for the detection of tuberculosis, still the diagnosis of TB is a challenging problem in this decade due to differences or non-specificity in symptoms, radiological signs, false negatives, and positives. Chest X-ray can identify the location, area, and morphology of lesions; hence analyzed the pattern and relation of chest X-ray and Gene expert ...
1949
1135
ANTIOXIDANT AND ANTIMICROBIAL POTENTIALS OF THE EXTRACTS OBTAINED FROM THE FIVE MARINE SPONGES COLLECTED OFF THE COASTS OF AGUSAN DEL NORTE, PHILIPPINES: AXINYSSA SP, PLOCAMIONIDA SP, FORCEPIA SP, PACHYMATISMA SP AND PLACOSPONGIA SP
Five marine sponges were collected off Carmen, Agusan del Norte, Philippines and taxonomically identified as Axinyssa sp., Plocamionida sp., Forcepia sp., Pachymatisma sp and Placospongia sp. The “non-polar” (EtOAc-MeOH) and “pola”r (EtOH-H2O) extracts of the marine sponges were prepared and subjected to 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, a total antioxidant ca...
1949
1037
ISOLATION OF AROMATIC AND MEDICINAL COMPOUNDS FROM ISODON NILGHERRICUS (BENTH.) H. HARA – AN ECONOMIC ASPECT
The secondary metabolites being defensive function in plants, the men also thought of using same to defend the chronic diseases by crud drugs or with some organic aromatic molecules. The phenyl groups and other functional groups are bonded together, forming aromatic organic molecules. These molecules are used in perfumes and medicines. The qualitative and quantitative aromatic and medicinal compou...
1948
1221