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PRELIMINARY SCREENING OF ANTI-CARIOGENIC PROPERTIES OF SELECTED MEDICINAL PLANTS AGAINST STREPTOCOCCAL DENTAL CARIES
Streptococcus mutans is the primary major causative agent of dental caries, with the ability to produce acid and form dental plaque. Streptococcus mutans adheres to the tooth surface via extracellular enzymes and produces dental plaque via extracellular polysaccharides synthesized from sucrose via glucosyltransferase and fructosyltransferase. This study aimed to look at the alternative antimicrobi...
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COMPARATIVE ANALYSIS OF PHYSICO-CHEMICAL PROPERTIES OF SOIL OF VIZAG NEAR BHEEMILI RIVER (ESTUARINE), WATER OF ANTARVEDI ANDHRAPRADESH STATE
Environmental changes influence Physical and Chemical reactions such as pH, Temperature, EC and chemical properties such as Dissolved Oxygen, Organic matter, Silica provide important information on Soil and Water quality different sources of variations and their effects on activities and biodiversity of Soil and Water. In the present study, the Physico-Chemical parameters of Soil sample from Vizag...
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LIVER PROTECTIVE ACTIVITY OF COCCINIA GRANDIS FRUITS EXTRACT AGAINST ANTI-TUBERCULAR DRUGS INDUCED LIVER TOXICITY IN RATS
To investigate the hepatoprotective activity of Coccinia grandis fruit extract against anti-tubercular drugs induced hepatotoxicity in rats. 50% ethanolic extract of Coccinia grandis (CGE 200 and 400 mg/kg body weight) was administered daily for 9 days in experimental animals. To develop hepatotoxicity, animals were administered orally with Isoniazid (50 mg/kg, p.o.) and Rifampicin (100 mg/kg, p.o...
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ISOLATION AND CHARACTERIZATION OF MULTI-DRUG RESISTANT (MDR) AND EXTENSIVELY DRUG RESISTANT (XDR) BACTERIA FROM DIVERSE ENVIRONMENTAL NICHES
Antimicrobial resistance (AMR) emerged as a major challenge to public health and significantly impacting the global economy. Infections due to multi-drug resistant (MDR) bacteria are difficult to treat and cause financial burden on patients. Environment may serve as a genetic pool of several drug resistant genes and help bacteria to emerge as notorious superbugs. This study aimed to characterize M...
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ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF LEAF EXTRACTS OF BERBERIS ARISTATA AND ABIES WEBBIANA: THE ETHNOMEDICINAL PLANTS
This study was carried out to investigate the antibacterial and antifungal potentials of Abies webbiana and Berberis aristate Linn. The study aims to assess the antimicrobial activity and determine the zone of inhibition of extracts on some bacterial and fungal strains. The extracts determined the antimicrobial activity using the agar disc diffusion method. The antibacterial and antifungal activit...
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HOME REMEDIES, DIETARY AND LIFESTYLE CHANGES DURING COVID-19 PANDEMIC
December 2019 has become one of the most surprising days in the whole world in light of the flare-up of a most infectious sickness brought about by novel Covid or Severe Acute Respiratory Syndrome Corona virus 2 (SARS-CoV-2). This study is conducted to assess the benefits of the use of home remedies to prevent the cause of Covid-19 and evaluate the assessment of dietary changes and physical activi...
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NANOGELS: AN OVERVIEW OF PROPERTIES, CLASSIFICATIONS, DRUG TARGETING METHODS, EVALUATION PARAMETERS AND APPLICATIONS
Nanogels (NGs) are advanced and innovative drug delivery systems that play an important role in remarking many issues that are associated with recent and trendy courses of treatment, such as non-specific effects and low stability. NGs could be well-defined as extremely cross-linked hydrogels (nano-sized) ranging from 20-200 nm. NGs are vigorous nanoparticles (NPs) used to deliver active ...
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PRECLINICAL SAFETY EVALUATION OF BERBERINE IN COMBINATION WITH GLICLAZIDE
Allopathic drugs are generally prescribed for Diabetes Mellitus (Type-II) patients. As the disease is chronic in nature, it necessitates the use of alternative medicine(s) either to supplement the existing allopathic therapy and/or to reduce the associated side effects with their chronic use. The use of herbal drugs is presumed to be safe option due to fewer side effects. However, evaluation of sa...
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PREPARATION AND STANDARDISATION OF PANCHA HARITHAKADI CHURNA BY HPTLC
Standardization of herbal formulation is essential to assess the quality of drugs for its therapeutic efficacy. Pancha Haritha kadi Churna (PHC) is a traditional poly herbal formulation meant for digestion which consists of five ingredients having digestive property. It is used for the treatment of Constipation and Bloating. Churna’s will play an important role in gastro intestinal problems and ...
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FORMULATION AND EVALUATION OF SATRANIDAZOLE BY SELF EMULSIFYING DRUG DELIVERY SYSTEM
Background: Satranidazole is a class II drug per biopharmaceutical classification systems with poor aqueous solubility and antiprotozoal and anti-bacterial properties. Aim: Therefore, the purpose of the present study was to enhance the solubility of Satranidazole using a self-emulsified drug delivery system (SEDDS). Methods: SEDDS was prepared using Satranidazole (10 mg) and dissolved in the oil p...
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