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AN UPDATE ON THE THERAPEUTIC POTENTIAL OF HEMIDESMUS INDICUS (INDIAN SARSAPARILLA)
Hemidesmus indicus (H. indicus), also known as Indian Sarsaparilla or Anantmul, is a plant with diuretic, demulcent, and diphoretic properties. It treats various illnesses, detoxifies the blood, and reduces Vata, Pitta, and Kaphadoshas. It has been shown in pre-clinical trials to reduce illnesses in everyday clinical practice. In order to effectively promote this herbal medicine, clinical trials a...
1903
1280
ASSESSMENT OF EPIDEMIOLOGY, PRESCRIBING PATTERNS, MEDICATION ADHERENCE AND IMPACT OF PATIENT EDUCATION ON DIABETICS IN A RURAL COMMUNITY
Background: There is a rise in a number of diabetes mellitus patients globally, but awareness of the disease, symptoms, medication use, associated complications, and comorbidities are low among Indians. The objective of the study was to evaluate the epidemiology of diabetes, prescribing patterns, and medication adherence and the impact of patient education on diabetes in a rural community. Methods...
1902
872
HPTLC METHOD DEVELOPMENT AND VALIDATION FOR THE IN-VITRO INTERACTION STUDY OF MEBENDAZOLE WITH ATORVASTATIN
By the HPTLC method, a mobile phase system comprising of Ethyl acetate: Toluene: Methanol (5:4:1v/v/v) was selected, and the detection was carried out at 280 nm. The Rf values were found to be 0.65 ± 0.03 and 0.27 ± 0.03 for Mebendazole and Atorvastatin, respectively, which showed a good separation. The method was validated as per ICH guidelines. The percentage RSD values of repeatability, intra...
1902
1053
ISOLATION, IDENTIFICATION AND SCREENING FOR BIOACTIVE COMPOUNDS WITH ANTIMICROBIAL ACTIVITIES FROM SUB-AERIAL CYANOBACTERIA OF EASTERN REGION, ODISHA
Background and Objectives: Cyanobacteria are rich in various bioactive compounds. This study aims to screen the antimicrobial activity of sub-aerial Cyanobacteria isolated from sub-aerial habitats (Old monuments and building facades). Materials and Methods: Crude aqueous and organic extracts were screened for phytochemical constituents and tested for their antimicrobial efficacy against human path...
1902
1006
ANTIOXIDANT AND ANTIMICROBIAL POTENTIALS OF THE EXTRACTS OBTAINED FROM THE FIVE MARINE SPONGES COLLECTED OFF THE COASTS OF AGUSAN DEL NORTE, PHILIPPINES: AXINYSSA SP, PLOCAMIONIDA SP, FORCEPIA SP, PACHYMATISMA SP AND PLACOSPONGIA SP
Five marine sponges were collected off Carmen, Agusan del Norte, Philippines and taxonomically identified as Axinyssa sp., Plocamionida sp., Forcepia sp., Pachymatisma sp and Placospongia sp. The “non-polar” (EtOAc-MeOH) and “pola”r (EtOH-H2O) extracts of the marine sponges were prepared and subjected to 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, a total antioxidant ca...
1901
1013
IN-VITRO ANTIDIABETIC AND ANTIOXIDANT ACTIVITIES OF AQUEOUS AND ETHANOLIC EXTRACT OF VITIS VINIFERA SEEDS
In the present study, the aqueous and ethanolic extracts of Vitis vinifera seeds were studied for alpha-amylase and alpha-glucosidase inhibition using an in-vitro model. The plant extracts were also examined for their antioxidant activities by using the free radical 1, 1-diphenyl-2-picryl hydrozyl (DPPH) scavenging method under in-vitro. The study revealed that the different concentrations of the ...
1901
991
MORPHOMETRY OF HUMAN SCAPULA GLENOID FOSSA AND ITS SURGICAL ANATOMY: AN OBSERVATIONAL STUDY IN EASTERN ODISHA
Introduction: Scapulae bear a shallow articular concave fossa commonly known as glenoid cavity that accommodates the head of the humerus to form a shoulder joint. The size and shape of glenoid fossa is highly variable; hence, knowledge about morphological measurements is invariably essential for surgery and artificial prosthesis pertaining to shoulder joint pathology. Aim: Glenoid fossa morphome...
1900
1044
FORMULATION DEVELOPMENT AND EVALUATION OF POLY AMIDOAMINE (PAMAM) DENDRIMERS AS POTENTIAL CARRIERS FOR ENHANCED TRANSDERMAL DELIVERY OF ITRACONAZOLE GEL FORMULATION
The drug of dendrigel, uses dendrimers as medicine carriers. Dendrimers were prepared by divergent growth techniques and were loaded in varying quantities in carbapol 934. To this mixture, itraconazole drug was added and the expression of dendrigel was estimated. Dendrimers were prepared by divergent growth techniques. Estimation parameters like color test, UV spectroscopy, and FTIR. Evaluation pa...
1900
1145
SOLUBILITY ENHANCEMENT OF LABETALOL HYDROCHLORIDE BY USING LIQUISOLID TECHNIQUE FOR MANAGEMENT OF HYPERTENSION
Background: Hypertension is the most common disorder affecting different age groups of people. The increased blood pressure creates discomfort in the patients; these cardiovascular diseases are risky which can lead to “mortality and morbidity”. Labetalol hydrochloride is an anti-hypertensive drug used to treat high blood pressure and Angina. These compounds possess less water solubility and lo...
1896
854
HYPOGLYCEMIC ACTIVITY PROFILE OF POLYHERBAL FORMULATION (PF) AND POTENTIATION OF HYPOGLYCEMIC EFFECT OF METFORMIN IN RODENTS
Polyherbal formulation (HF) containing different herbs have been used to treat diabetic patients by ayurvedic practitioners in India. The present study reports the effect of HF alone and with metformin on different rat models of hyperglycemia. HF treatment with HF alone and in combination with metformin elicited a significant hypoglycemic effect on epinephrine hyperglycemia and alloxan diabetic ra...
1896
961