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CHEMICAL COMPOSITION AND PUPICIDAL ACTIVITY OF ESSENTIAL OIL FROM MENTHA SPICATA AGAINST AEDES AEGYPTIL. (DIPTERA: CULICIDAE)
Mosquito-borne diseases are serious health problems in India, and mosquito vector control is a fundamental approach to control various diseases. Essential oils represent eco-friendly alternatives to costly synthetic pesticides for mosquito control. The essential oil of Mentha spicata in India was used for its activity against Ae. aegypti. The essential oil showed pupicidal activity against this mo...
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DESIGN, SYNTHESIS AND IN-VITRO ANTIMICROBIAL EVALUATION OF MANNICH BASE METAL COMPLEXES
Succinimide and its derivatives are important substitutes of many medicinal compounds in the pharmaceutical field. One of the essential objectives in heterocyclic and medicinal chemistry is the synthesis of molecules having importance as therapeutic agents. Heterocyclic compounds and their derivatives contain an imide ring that can easily cross biological membranes in-vivo. Mannich reactions are o...
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A STUDY ON THE ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY OF SCUTELLARIA DISCOLOR COLEBR IN EXPERIMENTAL ANIMALS
The genus Scutellaria has many species. But only a few species are investigated for the treatment of many ailments. Despite the extensive use of traditional medicine against several diseases, scientific studies of Scutellaria discolor are less. The present study is taken up to investigate the analgesic and anti-inflammatory actions of the acetone extract of S. discolour (SDA)using tail flick met...
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THE CURRENT REGISTRATION REGULATIONS OF COSMETIC PRODUCTS IN “BRICS” COUNTRIES
Omega-3 fatty acids are essential fatty acids present in regular animal and plant food diets. They play a key role in different body functions. Omega-3 fatty acids help to prevent central nervous system diseases. In this paper, we have shown the molecular basis of this effect. There isa number of studies showing the role of omega-3 fatty acids in the prevention of different central nervous system ...
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ANALGESIC ACTIVITY OF ETHANOLIC, HEXANE AND CHLOROFORM EXTRACTS OF SESAME SEED BY THERMAL HEAT METHOD IN ALBINO MICE
Background: Pain is a common symptom having huge public health importance. Conventional analgesics relieve pain effectively but cause various unwanted side effects. Hence the search for a novel analgesic with favourable risk-benefit profile is essential. Objectives: The current study was undertaken to investigate the analgesic activity of the ethanolic, hexane and chloroform extracts of sesame see...
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FUSION OF ZNO NANO/MINT EXTRACT LOADED PVP/PVA COMPOSITE BLEND: CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY
ZnO is used as a nanofiller in various concentrations to create flexible self-standing films of PVP-PVA mix composites. This work presents the results of structural, compositional, morphological, and optical analyses carried out using X-ray diffraction (XRD), Fourier Transform Infra-Red spectroscopy (FTIR), scanning electron microscopy (SEM), Thermo gravimetric analysis (TGA), and ultraviolet-visi...
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ESTIMATION OF TARTRAZINE IN FRUIT JUICES AND JAMS BY HPTLC METHOD DEVELOPMENT AND VALIDATION PARAMETERS
Tartrazine is a lemon-yellow synthetic food colourant belonging to azo group. The Acceptable Daily Intake (ADI) of tartrazine is 7.5mg/kg However, it is possible that more than permissible amount of Tartrazine is used to make food items more attractive. This may pose threat to consumer’s health. Hence the overall aim of the study was to detect and quantitate the presence of tartrazine in commerc...
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MOLECULAR MODELING STUDIES OF NOVEL N-(3-(BENZO[D]THIAZOL-2-YL)-4-((SUBSTITUTED BENZYL) OXY)PHENYL) ACETAMIDE AS EGFR INHIBITORS
Background: Cancer is continuing to be a major health problem in developing as well as undeveloped countries. It is a leading cause of mortality worldwide, accounting for most of the deaths. Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein, and mutations that lead to EGFR overexpression or overactivity have been associated with a variety of human cancers. Purpose: In-silico ...
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EVALUATION OF ANTI-ARTHRITIC ACTIVITY OF MICROSPONGE FORMULATION IN FREUND’S COMPLETE ADJUVANT-INDUCED ARTHRITIC RAT MODEL
The aim of the present study was to improve the release rate of herbal drugs by microsponges prepared through quasi-emulsion solvent diffusion technique using ethyl cellulose and PVA as carriers. The microsponges were characterized by FTIR, DSC and SEM studies followed by the determination of total drug content and entrapment efficiency. Anti-arthritic activity was evaluated by Freund’s Complete...
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GC-MS ANALYSIS AND IN-SILICO ADMET ANALYSIS OF THE AQUEOUS METHANOL LEAF EXTRACT OF ISODON TERNIFOLIUS (D. DON) KUDO
Medicinal plants contain phytocompounds which are of medicinal value. Scientific evaluation of these compounds that may serve as potential drugs is important in validating the medicinal plants. The leaf extract of the medicinal plant, Isodon ternifolius (D. Don) Kudo was prepared by the maceration method using 80% aqueous methanol as the extraction solvent. The resulting extract was subjected to ...
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