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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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3.

A REVIEW ON THE ANTISPASMODIC POTENTIAL OF SOME TRADITIONAL MEDICINAL PLANTS OF INDIA

For the treatment of many illnesses and disorders, including gastrointestinal (GI) ailments, several medicinal plants have been used. Most children and adolescents often suffer from GI illnesses, which have overlapping clinical manifestations in diagnosis and treatment requirements. In order to address the symptoms of smooth muscle contraction and cramping in gastrointestinal illnesses as well as ...

Jyotirmoy Das * and Khyatirupa Sarma

Department of Pharmaceutical Science, Girijananda Chowdhury University Guwahati, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.15(12).3406-15

3406-3415

1774

1196

42.

IN-SILICO ANTI-ULCERATIVE ACTIVITY EVALUATION OF SOME BIOACTIVE COMPOUNDS FROM CASSIA TORA AND BUTEA MONOSPORA THROUGH MOLECULAR DOCKING APPROACH

Background and Aim: In-silico approach is commonly the method for predicting and confirming drug design. Hence the present study was undertaken to evaluate in-silico the anti-ulcerative activity of some bioactive compounds from Cassia tora and Butea monospora through a molecular docking approach. Method: Docking is performed using 22 runs of the Lamarckian Genetic Algorithm with the grid box sized...

Lalchand D. Devhare * and Niharika Gokhale

Oriental College of Pharmacy and Research, Oriental University Indore, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.14(2).904-11

904-911

1773

901

12.

WOUND HEALING POTENTIAL OF CARALLUMA ADSCENDENS

The purpose of this current investigation was for screening the wound healing potential of Ethanolic extract of Caralluma adscendens (EECA) whole plant. Caralluma adscendens (Apocynaceae), a common medicinal plant in traditional Indian medicine. Mentions in folk medicine and existing data raised an outlook on this plant for evaluating wound healing potential. Ethanolic extract of Caralluma adscend...

Divya Yada *, Chaitnya Aindla and Uma Bandaru

Mall Reddy College of Pharmacy, Osmania University, Maismmaguda, Dhulapally, Secunderabad, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.15(2).409-14

409-414

1773

900

22.

PHYTOCHEMICAL ANALYSIS, ELEMENTAL CONTENT, AND FIBROBLAST PROLIFERATION ACTIVITY OF THE HYDRO-ETHANOLIC EXTRACT OF MORINGA OLEIFERA LAM LEAVES

Moringa oleifera is one plant that is multi-purposefully used for the prevention and treatment of numerous diseases. This study analyzed the phytochemical and elemental contents of M. oleifera leaf extract, and evaluated its effect on fibroblast proliferation, which is crucial for wound healing. M. oleifera leaf samples were collected, identified, and extracted using solvents of different polariti...

E. Oppong Bekoe *, E. Orman, N. A. Offei, K. Donkor and A. R. Aikins

Department of Pharmacognosy & Herbal Medicine, School of Pharmacy, University of Ghana, Ghana.

DOI: 10.13040/IJPSR.0975-8232.15(3).813-21

813-821

1773

1037

42.

ESTIMATION OF ANTIARTHRITIC ACTIVITY OF A POLYHERBAL FORMULATION AGAINST ADJUVANT INDUCED ARTHRITIS IN RATS

Objective: Rheumatoid arthritis (RA) is a systemic disorder which involves the activation of immune system against the self-tissues. The main targets of this disease are the joints. Being systemic, the development of this disease involves different mechanisms, and thus, the exact cause of this disease remains unknown. Although different drugs have been developed, none has been found to be the cure...

T. J. Mohan Rao *, Margret Chandira and B. S. Venkateswarlu

Vinayaka Mission's Research Foundation - Deemed to be University (VMRFDU), Sankari Main Road, Ariyanur, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.13(11).4712-18

4712-4718

1772

988

62.

OPTIMIZATION OF CULTURAL CONDITIONS TO ENHANCE BIOACTIVE METABOLITE PRODUCTION BY STREPTOMYCES OLIVOVERTICILLATUS VLK-15

The study was designed to optimize cultural conditions for enhanced production of bioactive compounds by Streptomyces olivo-verticillatus VLK-15 isolated from mangrove ecosystem of South Coast of Andhra Pradesh, India.  The soil dilution plate technique was employed for the isolation of actinobacteria using starch-casein agar (ISP-6) medium. The potent strain was identified as Streptomyces olivov...

Krishna Naragani *, Mani Deepa Indupalli and Vijayalakshmi Muvva

Department of Botany, Hindu College, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.12(12).6715-20

6715-6720

1771

845

20.

SCREENING OF PGPR TRAITS AND MONOCROTOPHOS PESTICIDE DEGRADATION PROPERTIES OF ACTINOBACTERIAL ISOLATES

Bioremediation of organic compounds and heavy metals has been recognized to be a successful and effective technique in rhizoremediation of soil toxicity using the beneficial microbes which produce different metabolites and enzymes to degrade the toxic compounds/ pesticides available in the soil. In the present study, actinobacterial isolates were explored and identified for bioremediation of soil ...

Ankita Rani *, Abhishek Mathur and Sanjay Gupta

Department of Biotechnology, School of Biosciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India.

DOI: 10.13040/IJPSR.0975-8232.14(2).731-39

731-739

1771

820

13.

COMPARISON OF THREE TECHNIQUES FOR THE DIAGNOSIS OF MALARIA IN RESOURCE-LIMITED SETTINGS: A MINI-REVIEW

Objective of this article is to review three techniques, routinely used rapid diagnostic tests (lateral flow immune chromatography) versus nucleic acid amplification test (NAT) versus Paper-based microfluidics for DNA diagnostics of Malaria, as diagnostic tests in detecting malarial infection among febrile illnesses, suspected of malaria. The major constraint for implementing NAT as a routine scre...

Neha Martin Honnalli and T. M. Desy *

Department of Biochemistry, KS Hegde Medical Academy, Nitte - DU, Mangalore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.13(1).125-29

125-129

1770

880

33.

IN-SILICO MOLECULAR DOCKING STUDIES OF FLAVANOIDS AS POTENTIAL ANTI-PARKINSONIAN AGENTS

Flavonoids are a class of Polyphenolic compounds found abundantly in plants. This study employs computational methods to predict the binding affinities and interaction patterns of selected flavonoids with the adenosine A2A receptor, Monoamine oxidase B (MAO-B enzyme), and Catechol-O-Methyltransferase (COMT enzymes). The docking simulations were performed using software packages such as iGEMDOCK wh...

Purushotham Gudise, Yaso Deepika Mamidisetti * and Mounika Konatham

Department of Pharmacology, School of Allied Healthcare Sciences Mallareddy University, Maisammaguda, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.15(12).3679-91

3679-3691

1769

777

45.

FORMULATION AND EVALUATION OF BOSWELLIC LOADED TRASFEROSOMES HYDROGEL TO TREAT PSORIASIS

Transfersomes, which may penetrate mammalian skin, are notably ultra deformable (ultraflexible) lipid supramolecular aggregates. A type of formulation carrier system called a transfersome can transport medications with both low and high molecular weights transdermally. Transfersomes enter the underlying viable skin in an undamaged state through skin's stratum corneum pores that are smaller than it...

Surbhi Sirswal * and Sanjay Singh

Siddhartha Institute of Pharmacy, Veer Madho Singh Bhandari Uttrakhand Technical University, Dehradun, Uttrakhand, India.

DOI: 10.13040/IJPSR.0975-8232.14(8).4054-60

4054-4060

1768

1118