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KASABACH-MERRITT SYNDROME – A COMPREHENSIVE REVIEW
Haemangiomas are vascular lesions caused by abnormal blood vessel proliferation, especially in children. Kasabach-Merritt syndrome (KMS) is a rare and life-threatening thrombocytopenia and consumptive coagulopathy associated with aggressive vascular tumors in infancy and younger children. Kasabach-Merritt phenomena is a unique phenomenon in kaposiform hemangioendotheliomas (KHE) and tufted angioma...
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DESIGN, SYNTHESIS, DNA-BINDING AND DOCKING STUDY OF 2,4-DIMETHOXY ACRIDONES AS CYTOTOXIC AGENTS
A series of novel N10 -substituted 2,4-Dimethoxy acridones were synthesized as potent cytotoxic agents. DNA-binding studies of the synthesized compounds were carried out by the HPLC method using Calf thymus DNA (CT - DNA) based on their affinity or intercalation with CT-DNA, measured by binding percentage. The compound 12 bearing planar dimethoxy tricyclic ring linked with butyl pyrazole side chai...
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VALIDATED SPECTROSCOPIC AND CHROMATOGRAPHIC TECHNIQUES FOR QUALITY CONTROL ANALYSIS OF APIGENIN IN HERBAL MEDICINES
The herbal medicines have been largely used since form several thousands of years in all developing and developed countries in the primary health care of community and society. Flavonoids are the class of polyphenolic secondary metabolites, which are mainly found in plants. Apigenin is a flavonoid which shows several pharmacological activities and used effectively for the management and treatment ...
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REVIEW ON PATHOPHYSIOLOGY OF MIGRAINE: TYPES AND VARIOUS ANTIOXIDANTS
The review briefs the information mainly about migraine disease. It tells about genes that are responsible for migraine. Alternating Hemiplegia in Childhood, Cortical spreading depression, Monogenic Migraine, Hemicrania Ophthalmoplegia, Hemicrania Alia Definite, Hemicrania, Complicated Migraine, Status Migrinous these are types of migraine, sign and symptoms also included. The history gives all th...
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AN EFFICIENT METHOD FOR ANTHER AND OVARY CULTURE IN ABELMOSCHUS ESCULENTUS (L.) MOENCH. IN-VITRO
Okra (Abelmoschus esculentus (L.) Moench.) is an important nutrient-rich vegetable crop also known as “lady’s finger”, widely grown in the tropics and sub-tropics mainly for its edible pods and is an alloploid. The haploid technique has been used in plant breeding for the improvements of plants and to develop new varieties in a relatively short time. Hence, we have optimized several factor...
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MILLET FOOD WASTE AS MEDICINE FOR MANAGEMENT OF LIFESTYLE DISORDERS
Plant foods are wasted especially in millets as they are not required in that particular product processing. From the cultivation of millet to its processing and consumption of the final product, a significant amount of waste is generated. Wasted foods are not spoilt foods and still have the potential to be used for the second time as food. But unfortunately, the fate of waste is always landfill...
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KNOWLEDGE, ATTITUDE, AND PRACTICE OF TYPE 2 DIABETES MELLITUS PATIENTS IN A TERTIARY CARE TEACHING HOSPITAL IN SOUTHERN ASSAM, INDIA
Background: Type 2 diabetes mellitus is increasing very rapidly in India, yet studies regarding knowledge, attitude and practices in diabetes in various Indian communities, especially in the Northeastern region, are limited. It is essential to understand the current gaps in knowledge and problems with the attitude and perceptions of the general population regarding diabetes to effectively plan pub...
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QUALITY ANALYSIS OF MARKET SAMPLES OF ŌRILA COLLECTED FROM DIFFERENT MARKETS OF KERALA USING PHARMACOGNOSTIC TOOLS
Ōrila is a well-known drug used in many Ayurvedic recipes in kerala. In most texts Ōrilais seen paired with Mūvilaand together they fare as components of the Daśamula. From very old Kerala commentaries of ancient Ayurvedic texts, Ōrila and Mūvila are seen as Malayalam translations of Pṛśniparṇī and Śālaparṇī respectively. In Kerala Pṛśniparṇīis often identified as Ōrila and...
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CONCISE OVERVIEW ON OVARIAN CANCER AND ITS TREATMENT PARP INHIBITOR, TARGETED DRUG THERAPY, IMMUNOTHERAPY AND MORE
The primary cause of death for women with gynaecological cancer diagnoses is ovarian cancer. It is also, generally speaking, the sixth most common cause of death for women. The majority of cases had advanced diagnoses, which worsens the disease's prognosis. The limited predictive value of the current screening tests adds even more suffering to the situation. The most important early detection tech...
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ALLODERM IN MULTIPLE ADJACENT GINGIVAL RECESSION: A SYSTEMATIC REVIEW AND META-ANALYSIS
Objective: Gingival recession is one of the most common mucogingival defects for which patients seek periodontal therapy. Treatment options for gingival recession include surgical procedures with pedicle flaps, free soft tissue grafts, gingival veneering, restorations, etc. When multiple gingival recessions involving adjacent teeth are present, the first choice is to address all recession defects ...
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