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NANOFORMULATION OF HERBALS: A QUANTUM LEAP IN MEDICINAL PLANT APPLICATIONS
Herbal medicines, with their rich history of use, often face challenges in achieving optimal effectiveness due to low absorption rates and limited bioavailability of their phytoconstituents. While these constituents are typically water-soluble, their inability to penetrate lipid membranes compromises their efficacy. To overcome these limitations, integrating herbal drugs with nanotechnology has em...
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IN-VITRO ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITY OF WHOLE PLANT EXTRACT OF BIOPHYTUM SPECIES
The whole plant of Biophytum reinwardtii (Zucc.) Klotzsch (BR) and Biophytum veldkampii A.E.S. Khan & et al. (BV) were evaluated for their antioxidant activities, total phenolic content (TPC), and total flavonoid content (TFC). The plants were successfully extracted with varying polarity solvents like pet ether, chloroform, ethyl acetate, and ethanol. Phytochemical evaluation of various extrac...
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PHARMACOGNOSTIC AND HPTLC COMPARISON OF KERALA MARKET SAMPLES OF BHARANGI (CHERUTHEK) WITH GENUINE SOURCE PLANT ROTHECA SERRATA (L.) STEANE & MABB
Background: Bhāraṅgī, herbal drug used in Ayurveda as Kapha-Vata samaka and indicated in Swasa, Kasa, Vrana, Shotha etc. It is an important ingredient in many of the preparations like Kantakaryavaleha, Kanakasava, Dasamularista, Lodhrasavam, Sudarsanasavam. As per API the accepted source of Bhāraṅgī is Rotheca serrata (L.) Steane & Mabb belongs to family Lamiaceae. There were ambient s...
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LABRAFAC WL1349 AIDED LYOPHILIZE SOLID DISPERSION OF OLMESARTAN MEDOXOMIL
Water solubility is the rate limiting step in dissolution and bioavailability. Olmesartan medoxomil is BCS class-II drugs having low water solubility. Olmesartan medoxomil acts on cardiovascular system and used in the treatment of hypertension as antihypertensive agent. Olmesartan medoxomil have low water solubility and low bioavailability as 26%. In this research study we made Olmesartan medoxomi...
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AN UPDATED STATUS OF ALANINE RACEMASE INHIBITORS: A REVIEW
Enzyme Alanine racemase is well known for performing the predominating role in mycobacterium cell wall synthesis. D-alanine provided by Alanine racemase serves as a peptidoglycan precursor, utterly vital for maintaining the growth and integrity of the cell wall. The lipid-rich mycobacterium cell wall is prevalent amidst prokaryotes with immense potential of becoming a therapeutic target for new dr...
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ETHNO-GYNECOLOGICAL KNOWLEDGE OF MEDICINAL PLANTS USED BY RURAL PEOPLE OF VILLAGES OF GURUGRAM DISTRICT, HARYANA INDIA
Ethnogynaecology is a young field of study that emphasize how indigenous people and local healers manage gynecological conditions in females. The goal of the current study was to record in-depth information about Ethnogynaecology in a previously unexplored region of Haryana. In the year 2022, a floristic and ethnomedicinal survey was conducted in Haryana, India in rural areas of Gurugram district....
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EVALUATION OF THE PHARMACOPHORIC ACTIVITY OF DIFFERENT COMPOUNDS OBTAINED BY GC-MS IN AQUEOUS EXTRACT OF LAWSONIA ALBA
Most of the medications currently in use are largely derived from the traditional plants and their products. Lawsonia alba, often known as henna, has a wide range of medicinal uses, from minor infections to cancer and is also used as a hair dye. All of these pharmacological actions and therapeutic uses are because of the presence of numerous secondary metabolites. These were isolated using the GC-...
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PHYTO-THERAPEUTICS IN BATTLE OF MULTIDRUG-RESISTANT INFECTIONS: A SYSTEMATIC REVIEW
Background: The unprecedented overuse and illogical prescribing of antibiotics for various illnesses has accelerated the evolution of antibiotic-resistant bacteria, which has contributed to the resurgence of pathogenic strains with strengthened resistance to conventional therapies. Rising resistance has threatened human health and increased the expense of treating diseases, compromising the treatm...
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A CROSS-SECTIONAL ANALYSIS OF HEALTH-RELATED MISLEADING ADVERTISEMENTS REPORTED BY SIDDHA REGIONAL RESEARCH INSTITUTE, PUDUCHERRY
Background: Misleading advertisements in the healthcare sector, particularly concerning Ayurveda, Siddha, Unani, and Homeopathy (ASU & H) products, pose significant risks to public health. Despite existing regulations, the prevalence of such advertisements remains a concern, necessitating comprehensive strategies for mitigation. Methods: This cross-sectional analysis examines misleading advert...
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DE RITIS RATIO OF COVID-19 PATIENTS ADMITTED DURING FIRST, SECOND AND THIRD WAVE
Background: To date, the 2019 novel coronavirus pneumonia (COVID-19) is the greatest public medical issue in the world. World Health Organization (WHO) declared this outbreak a “public health emergency of international concern” on January 31, 2020. Therefore, it bodes well to look for a potential biomarker that could quickly and effectively distinguish serious cases early. Of the total confirm...
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