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GC-MS ANALYSIS OF BIOACTIVE COMPOUNDS FROM THE METHANOLIC EXTRACT OF WHOLE PLANT OF CYNODON DACTYLON (L.) PERS.
Plants have been an important source of medicine with qualities for thousands of years. The therapeutic effects in the plants are due to the chemical compounds there in. Cynodon dactylon (L) Pers commonly known as Bermuda grass belongs to the family Poaceae. In ethnomedicinal practices, the plant Cynodon dactylon used in the treatment of various diseases and has pharmacological actions. Its health...
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METHOD DEVELOPMENT AND VALIDATION USING HPLC-ESI-MS/MS FOR DETERMINING STABILITY OF TALAZOPARIB IN BIOLOGICAL MATRICES
A highly sensitive, simple, accurate and precise HPLC-ESI-MS/MS method was developed and validated for the quantitative determination of talazoparib in biological matrices. The present study describes the determination of Talazoparib using validated protein precipitation method from human plasma employing Talazoparib 13C D4 as internal standard by electron spray ionization technique. Combination o...
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PRESCRIPTION ANALYSIS IN THE PATIENTS ADMITTED TO THE EMERGENCY MEDICINE DEPARTMENT AT TERTIARY CARE TEACHING HOSPITAL
Introduction: The Emergency Medicine Department presents distinct challenges, both diagnostic uncertainty and time constraints. Promptly administering the right drugs in this setting can be crucial for saving lives. Hence, we conducted a study to analyse the prescriptions in the patients admitted to Emergency Medicine Department. Method: This is a prospective, observational single center study con...
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BACTERIOPHAGE-MEDIATED MODULATION OF MULTIDRUG-RESISTANT PATHOGENS AND THEIR SUBSEQUENT ENCAPSULATION IN SODIUM ALGINATE MICROSPHERES
Antibiotic resistance is one of the gravest threats to human health today. Antibiotic resistance has emerged among hazardous bacteria due to the widespread use of drugs for human health, marine life, and agricultural animals. In contrast, bacteriophages are viruses that parasitize other bacteria for sustenance. A host cell is necessary for phage development and may be found practically everywhere ...
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METHOD DEVELOPMENT AND VALIDATION OF PARA-PHENYLENEDIAMINE IN PURE AND MARKETED DYES BY USING RP-HPLC
To estimate the presence of para-phenylenediamine in various commercial hair colors, a straightforward, speedy, precise investigation used High-Performance Liquid Chromatography to find PPD in henna and determine its presence. In order to do the chromatography, stationary phase Phenomenox C18 100 mm x 4.6 mm, 5µm column system was used for UV detection with a242 nm wavelength. The mobile phase Me...
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EFFECT OF CUSTOMIZED DASH DIET AND LIFESTYLE MODIFICATION ON BLOOD PRESSURE AMONG STAGE-1 HYPERTENSIVE INDIVIDUALS
This study aims to evaluate the impact of a personalized DASH diet and lifestyle modifications on blood pressure levels in individuals diagnosed with stage-1 hypertension. An observational study with purposive sampling was carried out over one-year duration, specifically from April 2022 to March 2023. Data was gathered through a self-structured interview schedule questionnaire and subjected to des...
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MOLECULAR CHARACTERISATION AND ANTAGONISTIC POTENTIAL OF MANGROVE STREPTOMYCES ISOLATED FROM COASTAL REGIONS OF ANDHRA PRADESH, INDIA
The main aim of the present study is to isolate and identify potent actinobacteria from mangrove sediments of SPSR Nellore district, Andhra Pradesh, India along with their antimicrobial activity. The samples collected were initially pretreated with calcium carbonate followed by dry heating. Dilution plate technique was employed to isolate actinobacteria employing two selective media viz. yeast ext...
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FORMULATION AND EVALUATION OF FLURBIPROFEN LOADED STEALTH LIPOSOME USING VARIOUS POLYMERS
Flurbiprofen (FP) is a phenyl alkanoic acid derivative and a family of non–steroidal anti-inflammatory drugs used in the treatment of arthritis. Flurbiprofen was formulated as a liposome using soya lecithin and cholesterol by thin film hydration method. It is then formulated as a stealth liposome to increase efficacy and reduce toxicity. Two polymers are used to prepare flurbiprofen as stealth l...
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GC-MS ANALYSIS AND ANXIOLYTIC ACTIVITY OF ESSENTIAL OIL OF SKIMMIA ANQUETILIA OF KASHMIR REGION
Medicinal plants essential oils in aromatherapy, complementary medicine or in folk medicine, is known for a long time or is gaining importance as a significant alternative method for the treatment of various ailments. In the last few years a lot of scientific studies have been conducted to investigate the effects and mechanisms of action of these natural compounds and their influence on the centra...
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PHARMACIST’S ROLE IN REPORTING AND PREVENTING MEDICATION ERRORS AT A GENERAL HOSPITAL IN MAKKAH, SAUDI ARABIA
Background: Medication errors significantly impact patient morbidity and mortality. Due to their specialized expertise, pharmacists are essential in detecting and averting these errors. Methods: This study evaluated pharmacists' roles in reporting and preventing medication errors at King Faisal Hospital in Makkah, Saudi Arabia. Using a cross-sectional method, we analyzed medication error reports t...
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