Most Popular
OPTIMIZATION OF THE FORMULATION AND IN-VITRO EVALUATION OF GABAPENTIN NIOSOMES FOR THE TREATMENT OF EPILEPSY
Objective: The main purpose of this current work is to optimize the formulation and in vitro evaluation of gabapentin niosomes. Methods: Niosomes are formulated by utilizing the thin film method. Gabapentin niosomes are prepared with cholesterol and span 80. Pre-formulation and post-formulation studies were carried out for optimized gabapentin niosomes. Such as FTIR, DSC, Zeta, Particle size, TEM,...
184
143
PATTERNS OF TOBACCO, BETEL NUTS AND SMOKE ABUSE IN RELATION TO MORPHOLOGICAL DIFFERENTIATION OF ORAL AND OROPHARNYGEAL SQUAMOUS CELL CARCINOMAS IN ASSAM
Background: Betel nut and different variants of tobacco and smoking is hazardous causing oral and or pharyngeal squamous cell carcinomas (SCC). In Assam, "Tamol", a raw, unprocessed betel nut is mixed with lime and betel leafis an alarming factor for oral and oropharyngeal SCC. Aim: To assess the patterns of tobacco, betel nuts and smoking causing variations in morphological differentiation of ora...
183
108
PRESCRIBING PRACTICES OF TOPICAL CORTICOSTEROIDS IN THE OUTPATIENT DERMATOLOGY DEPARTMENT OF A TERTIARY CARE TEACHING HOSPITAL
Introduction: Topical corticosteroids are mainstay of treatment for many skin conditions but extensive prescription of them may lead to increase in adverse reactions. So, periodic audit of prescriptions will help in enhancing the therapeutic effectiveness and reduce the adverse effects. Objective: To study sociodemographic data and drug prescription pattern in patients with skin diseases. Methodol...
183
101
A REVIEW ON PLANT OPILIA CELTIDIFOLIA: AN ASSESSMENT OF ITS BOTANY, CONVENTIONAL UTILIZATION, PHYTOCHEMISTRY AND PHARMACOLOGY
The plant Opilia celtidifolia, often known as ironwood or Opilia, is indigenous to many parts of Africa. It has a long history of traditional use in African herbal medicine, and its purported therapeutic benefits have attracted interest. An overview of Opilia celtidifolia's cultivation, the portions used, and the identification of its chemical components are given in this abstract. The savannahs, ...
183
107
ESTIMATION OF TARTRAZINE IN FRUIT JUICES AND JAMS BY HPTLC METHOD DEVELOPMENT AND VALIDATION PARAMETERS
Tartrazine is a lemon-yellow synthetic food colourant belonging to azo group. The Acceptable Daily Intake (ADI) of tartrazine is 7.5mg/kg However, it is possible that more than permissible amount of Tartrazine is used to make food items more attractive. This may pose threat to consumer’s health. Hence the overall aim of the study was to detect and quantitate the presence of tartrazine in commerc...
182
100
REVIEW ON SRC KINASES AS A PROMISING PHARMACOLOGICAL TARGET FOR VARIOUS DISEASES
This review explores the multifaceted roles of Src kinases, a subfamily of non-receptor tyrosine kinases, shedding light on their involvement in diverse diseases. Src-family protein tyrosine kinases (SFKs) exhibit widespread expression across various cell types, influencing their behavior and functionality. Src's presence in distinct subcellular locations, such as plasma membranes, perinuclear mem...
182
100
PHYTOCHEMICAL ANALYSIS, ELEMENTAL CONTENT, AND FIBROBLAST PROLIFERATION ACTIVITY OF THE HYDRO-ETHANOLIC EXTRACT OF MORINGA OLEIFERA LAM LEAVES
Moringa oleifera is one plant that is multi-purposefully used for the prevention and treatment of numerous diseases. This study analyzed the phytochemical and elemental contents of M. oleifera leaf extract, and evaluated its effect on fibroblast proliferation, which is crucial for wound healing. M. oleifera leaf samples were collected, identified, and extracted using solvents of different polariti...
181
113
SELENIUM AND CHROMIUM AS ANTIDIABETIC TRACE ELEMENTS: AN OVERVIEW
Trace elements are the dietary factors required by the body in small quantities for normal functioning of the body. The body’s functional skill is negatively impacted by a diet with insufficient trace elements, which lowers the body’s immune function. They are involved in catalyzing different enzymatic reactions. The permissible range of selenium is very narrow. Low levels of selenium have bee...
181
113
DEVELOPMENT OF A VALIDATED FORCED DEGRADATION STUDY FOR CHARACTERIZATION OF CICLESONIDE DEGRADANTS USING LC-MS
The stressed degradation study of Ciclesonide was conducted using various conditions, including acid, base, photolytic, thermal, and oxidative degradation. LC-MS was employed to characterize the degradants formed during these stress conditions. To assess the stability of Ciclesonide under stress, the study followed the guidelines outlined in ICH Q1A (R2). During the analysis, a C18 column (250mm x...
180
97
DEVELOPMENT AND CHARACTERIZATION OF ACECLOFENAC-LOADED NANOSPONGE GEL FOR THE MANAGEMENT OF RHEUMATOID ARTHRITIS
Rheumatoid arthritis is an autoimmune and inflammatory disease, in which immune system attacks healthy cells in your body by mistake, causing inflammation (painful swelling) in the affected parts of the body. Aceclofenac is a phenyl acetic acid derivative and NSAID with anti-inflammatory, analgesic and antipyretic effects. Nanosponges were prepared by the Emulsion solvent diffusion method with var...
179
106