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A COMPREHENSIVE REVIEW OF ANTIMICROBIALS AND NOVEL OPPORTUNITIES BY TRADITIONAL MEDICINE TO REVERSE ANTIBIOTIC RESISTANCE
An Antibiotic is an infectious disease that is the chief source for treating bacterial & fungal infections. The microbial resistance problem has been increasing daily, and the viewpoint for the usage of antimicrobial drugs is still undefined. Antimicrobial-resistant organisms are found in people, animals, food, plants, and in the environment. Do not use antibiotics to treat viral infections li...
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IN-VITRO INHIBITION AND DISSOLUTION OF CALCIUM OXALATE STONES BY THE FRACTIONS OF THE ZIZIPHUS LOTUS L. LEAVES
Nowadays, many clinical studies have provided reliable results on the effects of several herbal medicines on many diseases such as kidney problems. The objective of this study is to evaluate in-vitro the antiurolithiatic activity of polyphenols, flavonoids, and alkaloids fractions of the leaves of the species Ziziphus lotus. The quantification of the polyphenol and flavonoid fractions was carried ...
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CONCISE OVERVIEW ON OVARIAN CANCER AND ITS TREATMENT PARP INHIBITOR, TARGETED DRUG THERAPY, IMMUNOTHERAPY AND MORE
The primary cause of death for women with gynaecological cancer diagnoses is ovarian cancer. It is also, generally speaking, the sixth most common cause of death for women. The majority of cases had advanced diagnoses, which worsens the disease's prognosis. The limited predictive value of the current screening tests adds even more suffering to the situation. The most important early detection tech...
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NANOFORMULATION OF HERBALS: A QUANTUM LEAP IN MEDICINAL PLANT APPLICATIONS
Herbal medicines, with their rich history of use, often face challenges in achieving optimal effectiveness due to low absorption rates and limited bioavailability of their phytoconstituents. While these constituents are typically water-soluble, their inability to penetrate lipid membranes compromises their efficacy. To overcome these limitations, integrating herbal drugs with nanotechnology has em...
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COMPREHENSIVE REVIEW OF AUTOIMMUNE HEPATITIS: DIAGNOSTIC APPROACHES AND TREATMENT MODALITIES HIGHLIGHTED BY A CASE REPORT
Autoimmune hepatitis (AIH) is a chronic liver disease characterized by immune system dysfunction, elevated gamma globulins, and specific auto antibodies. It arises from genetic predisposition, environmental triggers, and immune dysregulation, and is typically managed with immunosuppressive therapy. The research highlights AIH risks, including disease recurrence and complications from vaccinations ...
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EFFECT OF EDUCATIONAL INTERVENTION ON MATERNAL KNOWLEDGE IN USE OF ANTIBIOTICS IN ACUTE RESPIRATORY INFECTIONS AMONG UNDER FIVE CHILDRENIN URBAN FIELD PRACTICE AREA OF MEDICAL COLLEGE BANGALORE
Background: Acute respiratory infections are the most important cause of mortality and morbidity among under-five children in developed and developing countries in the world. There is lack of awareness/ knowledge among parents regarding antibiotic use in children for minor respiratory ailments. Hence, the present study was undertaken. Methods and Methodology: After taking institutional ethical cle...
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A PROSPECTIVE STUDY OF DRUG PRESCRIBING PATTERN IN PSORIASIS AT A TERTIARY CARE TEACHING HOSPITAL IN SOUTHERN ASSAM, INDIA
Background: Environmental factors and genetics significantly impact the development of the chronic, inflammatory, debilitating, and proliferative skin disorder known as psoriasis. Erythematous plaques with distinct borders and silvery scales are signs of psoriasis. Objectives: This study aimed to study the pattern of drug use in psoriasis and to assess patient compliance. Materials & Methods: ...
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THE CONCENTRATION/RESPONSE FUNCTION BEHAVIORSOF NONCALORIC AND CALORIC SWEETENERS
Sweeteners are generally described in terms of their sweetness potencies relative to sucrose references. And, while caloric sweeteners have been found to have potencies invariant with sucrose reference concentration, noncaloric sweeteners decrease in potency as sucrose reference concentration increases. In this study, we develop methodology to determine the Concentration/Response functions for 9 (...
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METHOD DEVELOPMENT, VALIDATION, AND STABILITY INDICATING STUDIES OF HYDROCHLOROTHIAZIDE IN BULK AND PHARMACEUTICAL DOSAGE FORM BY UV-SPECTROSCOPY
Development of UV spectrophotometric method for the estimation of Hydrochlorothiazide was done by Q-Absorbance ratio method and area under curve method and stability indicating studies using methanol as solvent. In the present research, we have made an attempt to develop a simple, specific, accurate, precise and reproducible method for the estimation of hydrochlorothiazide by UV spectrophotometric...
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SYSTEMATICALLY REVIEWING THE HIGH-PERFORMANCE LIQUID CHROMATO-GRAPHY (HPLC) ANALYTICAL METHODS FOR DETERMINING METFORMIN IN DIFFERENT PHARMACEUTICAL FORMULATIONS AND HUMAN SAMPLES
Metformin (MET) is a biguanide class of oral hypo-glycaemic agent which is used in the treatment of diabetes mellitus type II. Currently, MET is the first drug of choice and is primarily prescribed by medical practitioners to at least 120 million people worldwide. The quality-oriented routine analysis of various commercially available products of MET is a major challenge. Several methods have been...
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