Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
ANTI-INFLAMMATORY AND ANTIBACTERIAL STUDIES ON INDIGOFERA LINIFOLIA RETZ.
Indigofera linifolia Retz(Fabaceae) is herb which spread throughout the India and found to be used by the tribal to cure inflammations. Based upon the review the present study focused on screening of Ant-inflammatory and Anti-bacterial activity of Indigofera linifolia Retz. The coarse powder of whole plant was extracted by cold maceration method using various solvents successively. Preliminary phy...
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EVALUATING THE EFFECT OF EXTRACT OF HALELA SIYAH (TERMINALIA CHEBULA RETZ) ON CHEMICALLY INDUCED CATALEPSY IN MICE
The objective of the present study was to evaluate the anticataleptic effect of Halela siyah (Terminalia chebula Retz) extract, on haloperidol induced catalepsy in swiss mice which were divided into four groups of six animals each. Animals in different groups were administered distilled water, scopolamine (1.0 mg/kg p.o) and hydroxy alcoholic (3:7) extract of Halela siyah (Terminalia chebula Retz)...
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MITOCHONDRIA: INSIGHT TARGET OF DRUG DEVELOPMENT IN CANCER CELLS
Mitochondria are involved in different physiological and pathological processes that are crucial for tumor cell physiology, growth and survival and its dysfunction leads to many human abnormalities, including cardiovascular diseases, neurodegenerative diseases, autoimmune disorders and cancer. The present review is focused on the different experimental and therapeutic cancer strategies addressed t...
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IN VITRO ANTIHELMINTIC ACTIVITY OF SOME MEDICINAL PLANTS: A REVIEW
Helminthiasis is infestation with one or more intestinal parasitic worms roundworms, whipworms , or hookworms in humans and animals. Presently, many synthetic drugs are available to treat Helminthiasis infection effectively, but suffer from number of side effects like abdominal pain, dizziness, headache, fever, nausea, vomiting, or temporary hair loss. Moreover, drug resistance is also another fac...
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BINDING EFFICACY AND ELUCIDATION OF QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP OF ACETANILIDE AND ITS DERIVATIVES WITH BOVINE SERUM ALBUMIN AND THEIR INHIBITION AGAINST COX1
Serum albumins are the most abundant proteins in plasma with many physiological functions. Among them, BSA has a wide range of functions involving the binding, transport and delivery of fatty acids, porphyrins, bilirubin, steroids, etc and it is home to specific binding sites for metals, pharmaceuticals and dyes. Recently, nanotechnology has become a popular term in the current science and technol...
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INHIBITION STUDIES OF TERPENE BASED NATURAL PRODUCTS WITH CYCLIN-DEPENDENT KINASE 4 (CDK4 MIMIC CDK2)
Cyclin dependent kinases (CDKs) are known as cell cycle regulators in eukaryotic cell cycle. Different CDKs (CDK2, CDK4 etc.) are having structure homology among them. Using computer based molecular modeling tools, interactions between naturally occurring terpene based compounds with crystal structure of CDK4 mimic CDK2 enzyme having PDB ID : 1GII. Using In-silico techniques, the binding energies ...
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A COMPARATIVE STUDY OF ROSIGLITAZONE AND PIOGLITAZONE TO EVALUATE THE CARDIOVASCULAR EFFECTS IN HIGH FRUCTOSE DIET INDUCED HYPERTENSIVE RATS
Thiazolidinediones (TZDs) were widely used for the treatment of type 2 diabetes. Recent studies have shown that TZDs have paradoxical effects on cardiovascular diseases. The objective of the present study was to investigate the effect of TZDs (Rosiglitazone and Pioglitazone) in High Fructose Diet (HFD) induced hypertension in rats. HFD was given for 14 weeks. After 8 weeks of hypertension inductio...
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PREVALENCE OF SERUM THYROID HORMONES AND MENSTRUAL IRREGULARETIES WITH INFERTILITY IN UTTAR PRADESH, INDIA
It is important to predict the serum thyroid hormones level in females during infertility to prevent its occurrence later on. In this study, we studied serum thyroid hormones and menstrual irregularities during infertility. A case control study was performed in 75 infertile patients with menstrual irregularities and 50 healthy matched women. Three biochemical parameters were measured in serum, hor...
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DASHAMULARISHTA: PHYTOCHEMICAL AND ANTIMICROBIAL SCREENING AGAINST EFFECT OF ENVIRONMENTAL POLLUTION
Pollution have a serious impact on human health and environment. The incidences of various diseases are becoming prominent with the increase in rate of population. The diseases mainly include respiratory disorders, cardiovascular disorders, throat inflammation, skin infections etc. In the present study, widely claimed crude drug Dashamularishta, have been screened for their antibacterial activit...
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ORAL AND SYSTEMIC SIDE EFFECTS OF CANCER CHEMOTHERAPY AND EFFECT OF BENZYDAMINE MOUTHWASH IN ORAL MUCOSITIS
Aim: To check the effectiveness of 0.15% Benzydamine hydrochloride on oral mucositis secondary to cancer chemotherapy Methods: In the past few years, multiple cases were referred to our department for the management of oral manifestations of cancer chemotherapy for various malignancies. Out of these patients, we selected 5 patients and used a simple, inexpensive treatment modality in considerat...
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