Objective: Gestational diabetes mellitus is defined as “carbohydrate intolerance resulting in hyperglycemia of variable severity with onset or first recognition during pregnancy, whether or not insulin is used and regardless of whether diabetes persists after pregnancy. There is evidence that asymptomatic hyperglycemia during pregnancy leads to important morbidity in the mother and foetus. Hence...
DEVELOPMENT AND VALIDATION OF STABILITY INDICATING UV SPECTRO-PHOTOMETRIC METHOD FOR THE ESTIMATION OF BENZYDAMINE HYDROCHLORIDE IN BULK AND IN PHARMACEUTICAL DOSAGE FORM: A NOVEL ANALYTICAL TECHNIQUE FOR CONDUCTING IN-VITRO QUALITY CONTROL TESTS
The objective of the present study is to develop and validate a novel stability indicating UV spectrophotometric method for estimation of Benzydamine Hydrochloride (BNZ) in pharmaceutical dosage form as not a single UV spectrophotometric method has been reported for the estimation of Benzydamine Hydrochloride, which makes the present work novel. In the present research work, UV spectrophotometric ...
COMPARATIVE ANTIOXIDANT POTENTIAL OF AQUEOUS AND ACETONE / WATER EXTRACTS OF GRAINS AND BRANS OF GRANIFEROUS SORGHUM [SORGHUM BICOLOR (L.) MOENCH] HYBRID GUANIPA 71 IN VITRO
Sorghum is an important food source with substantial nutritional value. An in vitro antioxidant evaluation of different extractions of graniferous sorghum [Sorghum bicolor (L.) Moench] hybrid Guanipa 71 was proposed here. Acetone / water extracts of both grains and brans revealed strong antioxidant properties by reducing Fe3+ (22.9% and 42.3%) and chelating Fe2+ (47.3% and 32.4%), respectively. Mo...
Seaweeds form economically important component of marine ecosystems worldwide. A wide range of beneficial and detrimental interactions exists between seaweeds and epiphytic as well as endophytic bacteria. Diversity study can be used to retrieve ecological information about community partner that relates the degree of stability of that community. The present work deals with the study the microbial ...
DESIGN AND EVALUATION OF AMOXICILIN TRIHYDRATE FLOATING GRANULES PREPARED BY MELT GRANULATION TECHNIQUE
The purpose of this study was to design and evaluate Amoxicillin trihydrate floating granules by melt granulation technique using Gelucire 43/01 and Campritol 888 ATO as lipid carriers. Polymers HPMC K4M and Ethyl Cellulose as release rate modifiers. The granules were evaluated by FTIR studies, differential scanning calorimetry, Scanning Electron microscopy, drug content, in vitro floating ability...
In this work, an attempt was made to synthesize new chalcones by Claisen - Schmidt condensation of substituted benzaldehydes with 4-aminoacetanilide in the presence of base catalyst. The synthesized chalcone derivatives was characterized by FT-IR, 1H-NMR, and 13C-NMR and also tested for their antimicrobial activity and compared with the standard drugs....
COMPARATIVE STUDY OF ROPIVACAINE WITH CLONIDINE AND ROPIVACAINE ALONE IN SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK
Background: Brachial plexus block provides minimal systemic impairment and excellent localized postoperative analgesia for upper extremity surgery. LA’s such as lignocaine, bupivacaine and ropivacaine are widely used along with adjuvant to improve the quality, onset and duration of block and to decrease postoperative analgesic requirement and systemic side effects. Adjuvant like α-2 agonist (Cl...
A diet rich in marine fishes and general seafood has long been recommended by several medical authorities as a long-term nutritional intervention to preserve overall health and wellbeing. An association between consumption of fish and seafood and beneficial effects on a variety of health outcomes has been reported in epidemiologic studies and clinical trials. These effects are mainly attributed to...
This study was carried out to investigate the acute oral toxicity LD50 of an anti-neoplastic and a chemotherapeutic agent hydroxyurea in male albino mice by using up α Down method. The result revealed that LD50 of hydroxyurea was (7868.5 mg/kg. b.w). Orally after 24 h of exposure. That’s mean it is slightly toxic agent. To study the effect of lethal doses of hydroxyurea on the some of blood par...
SUN PROTECTIVE FORMULATION FROM CAROTENOIDS EXTRACTED FROM THERMOTOLERANT GENERA SYNECHOCYSTIS PEVALEKII
Naturally occurring safe and broad spectrum UV blockers are required now- a- days to protect oneself from the onslaught of UV radiations that are known to cause many skin related ailments. The commercial inorganic sunblockers like Zinc oxide and titanium di oxide and organic sunblockers like Avobenzone and Benzophenone are known to be unstable and also their safety is doubted. Aim of the present c...