Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
DESIGN AND CHARACTERIZATION OF TOPICAL ANTIBACTERIAL FORMULATION CONTAINING EXTRACT OF QUERCUS INFECTORIA GALLS
Presently, the surge in the consumption of herbal formulations is encouraged by several factors; the main factor is that they are relatively safe and effective. Plant extracts are considered an alternative source of synthetic drugs and are expected to produce promising results for treating several diseases. The present study aimed to formulate and evaluate antibacterial thermosensitive mucoadhesiv...
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REVERSE AGING IN SACCHAROMYCES CEREVISIAE THROUGH REDUCED TOR1 EXPRESSION AND REPLICATIVE LIFE SPAN MODELLING WITH CELL VIABILITY ASSESSMENT USING PHYTOCHEMICAL EXTRACTS ALPINIA GALANGAL, COMMIPHORA MUKUL, ACORUS CALAMUS AND MORSHELLA ESCULENTA
To study reverse aging in Saccharomyces cerevisiae (S. cerevisiae) by gene expression analysis of target of rapamycin (TOR1) induced autophagy and replicative life span modelling (RLS) using Alpinia galangal (A. galangal), Commiphora mukul (C. mukul), Acorus calamus (A. calamus) and Morshella esculenta (M. esculenta). Methanolic extraction of plants was carried out using maceration. Activation of ...
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STUDY OF ANTINOCICEPTIVE EFFECT OF MELATONIN ALONE AND IN COMBINATION WITH PETHIDINE IN SWISS ALBINO MICE
Pain is the most common reason for physician consultation. Among the currently available analgesic drugs, opioids are the most efficacious but have many unacceptable adverse effects. Melatonin has been found to have antinociceptive potential in many animal and clinical studies that need further evaluation. The study aimed to assess the antinociceptive effect of melatonin alone and in combination w...
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MANNICH BASES OF 7-HYDROXY-4 -METHYL AND 4, 6, 7-TRIMETHYL COUMARINS AS POTENTIAL FUNGICIDES FOR ASPERGILLUS FLAVUS AND PYRRICULARIA ORZAE
Coumarin and its derivatives are widely used as scaffolds in synthesizing new heterocyclic systems. Numerous approaches especially involving nano-particle catalysts, have been developed to get new bioactive coumarin derivatives endowed with pharmacological and biological activities. The present work describes the reactivity and the new strategies for the synthesis of coumarin and its derivatives r...
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DEVELOPMENT AND EVALUATION OF HYDROCORTISONE-LOADED NIOSOMAL GEL
Objective: The present research work was to formulate optimize and evaluate hydrocortisone-loaded niosomal gel for the management of rheumatoid arthritis. Method: Niosomal gel was successfully prepared by lipid-thin film hydration process and optimized by using 23 full factorial designs using three independent variables (tween 80 concentration, cholesterol concentration, and sonication time) and t...
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AN RP-HPLC METHOD FOR THE QUANTITATIVE DETERMINATION OF REMDESIVIR IN INTRAVENOUS DOSAGE FORM
The worldwide epidemic of Coronavirus disease 2019 (COVID-19), caused by a new virus known as severe acute respiratory syndrome (SARS) coronavirus 2, has posed a growing threat to public health (SARS-CoV-2). The only antiviral drug authorized by the FDA for treating adult and pediatric patients hospitalized with a severe disease is remdesivir, which is given intravenously (IV). Although only a few...
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BIOACTIVE METABOLITE PRODUCTION BY TRITIRACHIUM EGENUM ISOLATED FROM SOUTHEAST COAST OF ANDHRA PRADESH, INDIA
A study has been undertaken to isolate potent fungi from the South-east coastal zone of Andhra Pradesh. Among the 11 fungal strains isolated and screened, one potent strain with broad-spectrum antagonistic activity was found. Based on the morphological, cultural, and molecular characteristics, the potent strain was identified as Tritirachium egenum. Production of bioactive metabolites by the strai...
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DEVELOPMENT AND OPTIMIZATION OF TRANSDERMAL MICROEMUSION FORMULATION OF BCS CLASS II ANTIDIABETIC DRUG BY DOE
The main aim of present investigation was to examine the potential of a microemulsion formulation developed through simplex lattice design as well as desirability function approach for transdermal delivery of BCS class II anti diabetic drug Glibenclamide. Pseudo-ternary phase diagrams were plotted by water titration method for multiple microemulsion formulations using oleic acid (oil), tween 80 ...
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FORMULATION AND EVALUATION OF NABUMETONE LOADED TRANSFERSOMAL GEL
Nabumetone (NBT), a non-steroidal anti-inflammatory drug used to treat rheumatoid arthritis, is rapidly metabolized in the liver and is well known for its side effects along with its sensitivity to light; thus, it limits the formulation of a such drug when considered for skin formulations. Recently introduced a new type of carrier for bioavailability benefits and patient compliance, the “transfe...
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UNRAVELING THE PHYTOCONSTITUENTS OF SCHLEICHERA OLEOSA AS AN ANTI-ARTHRITIC ACTIVITY: GC-MS ANALYSIS AND MOLECULAR DOCKING STUDIES
Rheumatoid arthritis is a systemic autoimmune and inflammatory disease that primarily affects the synovial joints and eventually destroys them. Schleichera oleosa is a plant of Indian provenance that exhibits anti-rheumatoid arthritis activity. The phytochemical constituents in the methanol extract of barks from Schleichera oleosa were identified using gas chromatography-mass spectrometry (GC-MS) ...
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