Pages Menu
ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

Categories Menu

Volume 1 (2010) - Issue 2, February

Review Articles

 
Title
Views
PDF
Cited
1.

PHOSPHATIDYLCHOLINE: A REVOLUTION IN DRUG DELIVERY TECHNOLOGY

In recent years Phosphatidylcholine has greatly impacted the drug delivery technology. The very first and most important advantage of phospholipid based vesicular system is the compatibility of phospholipids with membrane of human either internal membrane as well as skin (external membrane). For a drug to be absorbed and distributed into organs and tissues and eliminated from the body, it must pas...

P. VERMA *, A. RAM, A. K. JHA, A. MISHRA, A. THAKUR

Shri Shankaracharya Institute of Pharmaceutical Science*, Bhilai (C.G.), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).1-12

1-12

6268

1604

2.

MULTIPLE SCLEROSIS: A REVIEW

Multiple sclerosis affects around 2.5 million people worldwide it is one of the most common neurological disorders and cause of disability of young adults, especially in Europe and North America. There is a lack of epidemiological studies from Asia where the prevalence is reported to be low, though, with the availability of more neurologists and magnetic resonance imaging, a larger number of patie...

ASHWANI ARYA

Bharat Institute of Science, Tech. & Management, Pehladpur, Kurukshetra (Haryana), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).13-23

13-23

3169

1153

3.

HERBAL TREATMENT FOR URINARY STONES

Herbs and herbal drugs have created interest among the people by its clinically proven effects like immunomodulation, adaptogenic and antimutagenic. Also, the overuse of synthetic drugs, which results in higher incidence of adverse drug reactions, has motivated humans to return to nature for safe remedies. The problem of urinary stones or calculi is a very ancient one and many remedies have been e...

HAVAGIRAY R. CHITME *, SHASHI ALOK , S. K. JAIN , MONIKA SABHARWAL

Oman Medical College *, Muscat, Sultanate of Oman

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).24-31

24-31

18726

4558

Research Articles

 
Title
Views
PDF
Cited
4.

FORMULATION OF MEDICATED CHEWING GUM OF ONDANSETRON HYDROCHLORIDE AND ITS PHARMACOKINETIC EVALUATIONS

An attempt has been made to formulate new chewing gum device for ondansetron hydrochloride in the form of tablet. The new drug delivery system was obtained, at room temperature, by direct compression using conventional pharmaceutical equipment. The resulting chewing gum tablets comprise a gum core combined with fillers, antioxidants, coloring agent and plasticizers, which provide smooth appearance...

UPENDRA NAGAICH*, VANDANA CHAUDHARY, ROOPA KARKI, AKASH YADAV, PRAVEEN SHARMA

Acharya & B.M. Reddy College of Pharmacy*, Bangalore, (Karnataka), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).32-40

32-40

4673

1560

5.

SYNTHESIS AND ANTIDIABETIC EVALUATION OF SOME THIAZOLIDINE-2, 4-DIONE DERIVATIVES

Condensation of thiaourea with chloro acetic acid gave Thiazolidinedione which react with aromatic aldehyde and   produce 5- benzylidine, 2, 4 Thiazolidinedione.To this different secondary amine was reacted and final derivatives was obtained. The structures of these compounds were established by means of IR, 1 H-NMR.All the compounds were evaluated for antidiabetic activities. Most of the compou...

ASHUTOSH MISHRA, GAUTAM V.*, GHANSHYAM, BANDANA SINGH, SWEEMIT J., SAROJ KUMAR

A.N.D College of Pharmacy*, Bhabhnan, Gonda, (U.P.), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).4150

41-50

4114

1226

6.

ANTISPASMODIC AND ANTHELMINTIC ACTIVITY OF NYCTANTHES ARBORTRISTIS LINN.

Antispasmodic activity of the ethanolic extracts of different parts of Nyctanthes arbortristis Linn. was estimated using guinea pig ileum preparation against acetylcholine. Anthelmintic activity was tested following the method described by Kailashraj and Kurup, using earthworm (Pheretima posthuma). The extracts exhibited antispasmodic activity, which was less than that of piperazine citrate. The e...

SANJITA DAS*, DINAKAR SASMAL, SAUMYA PRIYA BASU

Department of Pharmaceutical Technology, Noida Institute of Engineering and Technology*, Greater Noida, (U.P.), India

DOI: DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).51-55

51-55

5274

1714

7.

POTENTIATIVE ACTIVITY OF CUCURBITA MAXIMA SEED EXTRACT WITH BETA VULGARIS & SMILAX REGELII ROOT EXTRACT TO REDUCE EXTRA FATS FROM THE BODY

Root Extracts of Beta vulgaris; Smilax regelii; & Cucurbita maxima. seed is effective for reducing fats individually as well as its combination effort through different mechanism. First one is used to flush out fats from the system and the second & third is used to regulate thyroxine. The extract of A,B & C were taken with diffusion extraction, ethanol extraction through soxhlet appara...

RAKESH DAS *, JAGDISH SAHU, R.N. GUPTA

Department of Pharmaceutical Technology, Jadavpur University, Kolkata (West Bengal), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).56-62

56-62

3339

1212

8.

EVALUATION OF ANTICONVULSANT ACTIVITY OF THE LEAVES ETHANOLIC AND AQUEOUS EXTRACTS OF NYCTANTHES ARBORTRISTIS LINN. AGAINST SEIZURES INDUCED BY PENTYLENETETRAZOLE AND ELECTROCONVULSIVE SHOCK IN MICE

Nyctanthes arbortristis Linn. (Oleaceae) which has been used as an antiepileptic remedy in tribal people of India (Orissa and Bihar) along with its use in Ayurveda, Sidha and Unani systems of medicine was evaluated for anticonvulsant activity against experimental seizures. The leaves ethanolic and aqueous extracts of N. arbortristis protected mice against tonic convulsions induced by maximal elect...

Dharmendra Singh*, V.B. Maurya, Kiran Prajapati, Hemant Kumar, Pankaj S. Niranjan and S. K. Jain

Department of Pharmacy, VBS Purvanchal University*, Jaunpur (U.P.), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).63-71

63-71

3116

1248

9.

A STUDY ON PRELIMINARY PHYTOCHEMICAL AND DIURETIC ACTIVITY OF BARK OF THESPESIA POPULNEA

Thespesia populnea is a reputed ever green tree belonging to the family malvaceae; commonly known as Indian tulip tree. The plant is distributed tropical regions and coastal forest in India. It is well known and all the parts are used in traditional system of medicine. The plant has been used as astringent, antibacterial, hepatoprotective, haemostatic, anti-diarroheal and anti-inflammatory. The sh...

R. PARTHASARATHY*, R. ILAVARASAN, RUPALI NANDANWAR

Bharath University, Selaiyur*, Chennai, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).72-77

72-77

4713

1522

10.

SYNTHESIS OF SOME N-HETROCYCLIC ANALOGS OF VASICINE

Vasicine is a pyrralazoquinazoline monobasic alkaloid obtained from the Plant Adhatoda vasica. In the present paper, the experiment were carried out to synthesis the various analogs of Vasicine, where the five membered ring C, was converted to seven membered ring, thus producing 7,8,9,10-Tetrahydroazepino[2,1-b] quinazolin-12(6H)one (RLX), was reported to be 6-10 times more potent than aminophylli...

N. MAHAJAN*1, K. L. DHAR, O. P SURI, K. NEPALI, N. KAMRA., A. GARG, A. SHARMA

Department of Pharmaceutical Sciences, Lovely School of Pharmaceutical Sciences, Lovely Professional University*, Phagwara, Punjab., India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).78-87

78-87

3343

1144

11.

ANTIMICROBIAL ACTIVITY OF BASELLA RUBRA LEAVES

The antimicrobial activities of aqueous, ethanolic and petroleum ether extracts of the leaves of Basella rubra were evaluated in the present study by measuring the inhibition zones using Cup Plate Diffusion method. The inhibition zones were significantly different (P<0.001) in each plant extract. The ethanolic extract showed maximum activity with zone of inhibition (14.3±1.82 mm) against E.col...

K. SEN *, A. GOEL, S. RAWAL, N. MAHAJAN, S. BABOO, S. ALOK

Department of Pharmaceutical Sciences, Lovely School of Pharmacy, Lovely Professional University, Phagwara (Punjab), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).88-91

88-91

9724

1827