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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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48.

FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF ACETAMINOPHEN

The present research work has been carried out for an optimized formulation of co-processed directly compressible vehicles in the preparation of the Acetaminophen mouth fast dissolving tablets (MFDTs). Acetaminophen was chosen due to its poor compression properties. Di-calcium Phosphate(DCP) was incorporated in the neutralized aqueous starch dispersion to prepare co-processed excipient. Co-process...

Abhay Kumar Mourya*, Sunil K. Prajapati , S.K. Jain , Ajay Kumar, Atul Kumar Thakran and Shashi Alok

Institute of Pharmacy, Bundelkhand University,Jhansi, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(2).610-14

610-614

5960

1531

39.

ANTIOXIDANT AND ANTILEUKEMIC ACTIVITY OF VITEX NEGUNDO LEAF EXTRACTS

Vitex negundo is an Indian medicinal plant used to cure several diseases such as asthama, fever, headache, cancer and many other diseases. This study aims to determine the antioxidant potential and anti-proliferative activity of Vitex negundo methanolic leaf extract. Isolation of bioactive compounds involved liquid-liquid extraction of methanolic leaf extract by petroleum ether and chloroform. The...

G. N. Shubha *, K. N. Shanti, Rukmini Jonnalagadda, Richa Kamboj and Sucheta Sridhar

Department of Biotechnology, PES Institute of Technology, Bangalore, Karnataka, India

DOI: DOI: 10.13040/IJPSR.0975-8232.7(12).5056-61

5056-5061

5957

1497

11.

ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF VARIOUS BREAD FRUIT LEAVES (ARTOCARPUS ALTILIS (PARKINSON) FOSBERG)

Breadfruit (Artocarpus altilis (Parkinson) Fosberg) empirically has been used in certain communities in Indonesia as a traditional medicine. Biosynthesis process can change colour leaves of breadfruit from green leaves (GL), yellow leaves (YL), fallen yellow (FY), fallen dry (FD), and the process fermentation of green leaves become fermented green (FG). The purpose of this study was to determine w...

Hesti Riasari *, Maria Ulfah, Diki Prayugo and Nurul Annisa Komariah

College of Pharmacy Indonesia Jl. Soekarno-Hatta No.354 (Parakan Resik), Bandung, Indonesia.

DOI: 10.13040/IJPSR.0975-8232.8(3).1066-73

1066-1073

5956

2389

18.

PHYTOCHEMISTRY, ANTI-CANCER AND ANTI-INFLAMMATORY ACTIVITIES OF SOLVENT LEAF EXTRACTS OF NYCTANTHES ARBOR – TRISTIS

Ayurveda is one of the oldest systems of medicine that uses plants and their extracts for treatment and management of various diseased states. Nyctanthes arbour - tristis Linn. (Family Oleaceae), which has long been used traditionally for various medicinal purposes in the Indian sub continent. Each part of the plant has some important medicinal value and is thus commercially exploitable. It is now...

T. D. Sandhya Kumari and M. A. Singara Charya *

Department of Microbiology, Kakatiya University, Warangal, Telangana, India

DOI: 10.13040/IJPSR.0975-8232.8(4).1654-63

1654-1663

5955

1564

7.

BIOCIDAL EFFICACY OF SYNTHETIC COPOLYESTERS HAVING CHALCONE MOIETY

Two chalcone diols (2E)-1-(4-hydroxyphenyl)-3(4-hydroxy, 3-ethoxy phenyl) prop-en-1-one and (2E)-1-(4-hydroxy-3-methoxy phenyl)-3(4-hydroxy, 3-ethoxy phenyl) prop-en-1-one were synthesized by acid catalyzed ClaisenSchmidt reaction. The synthesized chalcones were made to undergo polymerization using three aliphatic dichlorides namely glutaryl, succinyl and oxalyl chlorides. The polymers were random...

Rajesh Kumari and Tom John *

Neuropharmacology Section, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA

DOI: 10.13040/IJPSR.0975-8232.7(9).3611-16

3611-16

5954

1324

44.

A STUDY ON ASSESSMENT OF KNOWLEDGE, ATTITUDE AND PRACTICE REGARDING PHARMACOVIGILANCE AMONG HEALTHCARE PROFESSIONALS IN A TERTIARY CARE HOSPITAL, ANDHRA PRADESH

Objectives: The aim of this study was to assess knowledge, attitude and practice of the healthcare professionals about Pharmacovigilance in a tertiary care hospital, Rajahmundry, Andhra Pradesh. Materials and Methods: A cross-sectional questionnaire based study was carried out on healthcare professionals (Faculties, Postgraduates, Interns & Nurses) to assess the knowledge, attitude and practic...

Ravi Babu Komaram * and Midan Dhar

Department of Pharmacology, GSL Medical College & General Hospital, Rajahmundry, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.7(12).5082-87

5082-5087

5951

1111

13.

RECENT ADVANCES IN HOT MELT EXTRUSION TECHNOLOGY

Melt extrusion process which is well known in the polymer and food industry is now being used for pharmaceutical manufacturing to create innovative new formulations and is a continuous process of mixing and designing moldable materials. It is one of the most widely applied processing techniques useful for preparing solid dosage forms, granules, pellets, suppositories, implants, stents, ophthalmic ...

S.R. Kolhe*, P. D. Chaudhari and D.M. More

C-302, Waghire Empire, Near City International School, Morwadi, Pimpri, Pune- 411018, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(12).4659-69

4659-4669

5949

1739

1.

PHOSPHATIDYLCHOLINE: A REVOLUTION IN DRUG DELIVERY TECHNOLOGY

In recent years Phosphatidylcholine has greatly impacted the drug delivery technology. The very first and most important advantage of phospholipid based vesicular system is the compatibility of phospholipids with membrane of human either internal membrane as well as skin (external membrane). For a drug to be absorbed and distributed into organs and tissues and eliminated from the body, it must pas...

P. VERMA *, A. RAM, A. K. JHA, A. MISHRA, A. THAKUR

Shri Shankaracharya Institute of Pharmaceutical Science*, Bhilai (C.G.), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).1-12

1-12

5941

1500

31.

DEVELOPMENT AND VALIDATION OF A NEW HPLC METHOD FOR THE ESTIMATION OF AZITHROMYCIN IN BULK AND TABLET DOSAGE FORM

A simple, reproducible and efficient reversed phase high performance liquid chromatographic (RP-HPLC) method has been developed for quantitative determination of azithromycin in drug substance. The separations were carried out on a Xterra C18 column (150 ×4.6 mm; 5µ) with UV detection at 215 nm. The mobile phase consisting of acetonitrile and phosphate buffer (pH adjusted to 7.5) in a ratio of 5...

Irin Dewan*, Tasnuva Amin , Md. Faisal Hossain , Moynul Hasan , Sayeeda Fahmee Chowdhury , Mahjabeen Gazi and S.M. Ashraful Islam

Assistant Professor, Department of Pharmacy, University of Asia Pacific, Dhanmondi, Dhaka-1209, Bangladesh

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(1).282-86

282-286

5929

1706

32.

ASSESSMENT OF ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL SCREENING OF COLOCASIA ESCULENTA CORM

Colocasia esculenta corm aqueous extract was assessed for its in vitro antioxidant capacity and free radical scavenging potential by seven different assays, viz. total phenolic content, total flavonoid content, total flavonol content, reducing power estimation as well as 1,1-diphenyl-2-picrylhydrazyl (DPPH), nitric oxide (NO) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radic...

Manjulika Yadav, Devesh Kumar Kushawaha, Sanjukta Chatterji and Geeta Watal *

Alternative Therapeutic Unit, Drug Development Division, Medicinal Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.8(4).1758-64

1758-1764

5929

1408