Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
ELECTROCHEMICAL BEHAVIOUR OF OMEPRAZOLE INTERACTING WITH MYCIN DERIVATIVES AND DOXYCYCLINE
The interaction of omeprazole with different types of antibiotics was investigated in biological buffer at physiological pH=7.4 by using electrochemical (cyclic and linear sweep voltammetry) method. The reduction processes of omeprazole in the absence of and in the presence of azithromycin, clarithromycin, roxithromycin and doxycyclline are irreversible. Omeprazole interacts in solution with antib...
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PREDICTION OF LD50 OF SOME COMMON PESTICIDES THROUGH QSAR (AN ALTERNATIVE METHOD TO SAVE EXPERIMENTAL ANIMALS)
The most common test of acute toxicity is the LD50 test. LD50 means, the lethal dose of a substance that will kills 50% of animals. But this requires large number of animals. To reduce the sacrifice of animals. In present study we are using QSAR based software T.E.S.T. (toxicity estimation search tool 4.1 version) for predicting oral LD50. For prediction of oral LD50 we have taken 100 insecticides...
5629
2055
EXPLORING ANTIOXIDANT ACTIVITY AND DNA PROTECTION POTENTIAL OF CHONEMORPHA FRAGRANS
Chonemorpha fragrans (Moon) Alston is a liana belongs to family Apocynaceae. Due to its ethanobotanical importance, it is used intraditional medicinal systems as a part of various medicinal preparations. In the work presented here the plant has been explored for its antioxidant potential and DNA protection ability. The antioxidant potential of C. fragrans was determined using DPPH, FRAP, Phosphomo...
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2225
IN VITRO EVALUATION OF ANTIOXIDANT ACTIVITY AND TOTAL PHENOLIC CONTENT OF METHANOLIC EXTRACT OF PIPER BETEL
The Piper betel is an evergreen and perennial creeper belonging to the Piperaceae family, with glossy heart-shaped leaves and white catkin. It is valued both as a mild stimulant and for its medicinal properties. The total phenolic content of methanolic leaves extract was estimated by Folin-Ciocalteu assay method, and was found to be 0.110 mg/CE/g (Catechine Equivalent per gram). However, anti...
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1860
FUNCTIONALIZATION OF THE SELECTED REGENERATED CELLULOSIC FABRICS WITH HERBAL OIL AND EVALUATE THE FUNCTIONAL PROPERTIES
In this study, an attempt has been made to approach of developing antibacterial finish using aromatic herbal oils. The five different herbal oils like Palmarosa, Petitgrain, Tea tree, Thyme, Lavender oil were screened with disc diffusion method against bacteria that normally exist like Staphylococcus aureus, Escherichia coli. The result showed good efficiency in Thyme oil when compared to other oi...
3958
1932
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF TENOFOVIR DISOPROXIL FUMERATE AND EFAVIRENZ IN BULK AND FORMULATION
The objective of the present work was to develop a simple, rapid, accurate RP-HPLC method for the simultaneous estimation of Tenofovir disoproxil fumerate (TDF), Efavirenz in bulk and formulation. The chromatographic separation was achieved by isocratic mode of elution by using Agilent Zorbax Eclipse XDB C18 (150 x 4.6mm, particle size 5µm) analytical column. The mobile phase consisting of Aceton...
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CRYSTAL MODIFICATION OF ATOVAQUONE IN PRESENCE OF POLYETHYLENE GLYCOL (PEG) 4000
Atovaquone is a hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols. Its inhibitory effect being comparable to ubiquinone, in sensitive parasites atovaquone can act by selectively affecting mitochondrial electron transport and parallel processes such as ATP and pyrimidine biosynthesis. It exhibits low bioavailability related to its poor water solubilit...
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IN-VITRO EVALUATION OF ANTIOXIDANTS ACTIVITY OF ETHANOLIC LEAVES EXTRACT OF CELASTRUS PANICULATUS
Celastrus paniculatus is an important medicinal plant used in India. Traditionally seed oil of this herb is used widely in several medicinal preparations and its bark is used in malaria in folk medicines. It is endangered and vulnerable plant. The investigation used Reducing power assay and Total phenolic content to determine antioxidant potential in the ethanolic extract of the drug. The result s...
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1819
DYNAPAR AQ IV BOLUS INJECTION FOR POSTOPERATIVE PAIN
Aim: To evaluate safety and efficacy of diclofenac 75 mg/1ml (Dynapar AQ) administered as IV bolus versus diclofenac 75mg/3ml administered as IV infusion in patients with postoperative pain. Methods: 350 postoperative adult patientswere randomized to receive either treatment. Primary efficacy endpoints were time to onset of analgesia and postoperative pain intensity while secondary efficacy end...
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PHYTOCHEMICAL SCREENING STUDY AND CONSTIPATION ACTIVITY OF SPERMACOCE HISPIDA L. (RUBIACEAE) BY USING ALBINO RATS
The whole plant of Spermacoce hispida L is reported to have great medicinal value.It is found effective systemically in treating, headache, constipation, anti-hypertensive, anti-fertility, Appetite, Scabies, Irritant bowel syndrome and skin disease etc. Intake of 2 to 4 g of the seeds along with a mixture of dry ginger, coriander seed andfinger millet reduces the unwanted cholesterol namely LDL an...
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