Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
LORNOXICAM AND FRANKINCENSE OIL TRANSDERMAL GEL: A POTENTIAL FORMULATION FOR MANAGEMENT OF INFLAMMATION
Inflammation is usually accompanied by pain. The pathogenesis of pain involves not only nociception i.e. the aspect related to sensation of pain but also the emotional aspect involving the pain related fear and stress. Lornoxicam is a non-steroidal anti-inflammatory drug of oxicam class. Frankincense oil, used commonly in aromatherapy, has been known to have calming and grounding effect on emotion...
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STRUCTURE BASED MOLECULAR DOCKING STUDIES ON SOME 1,3-DISUBSTITUTED UREA DERIVATIVES AS ANTI-TUBERCULAR AGENTS
Docking is a method which predicts the preferred orientation of one molecule to a second when bound to each other to form a stable complex and is frequently used to predict the binding orientation of small molecule drug candidates to their protein targets and plays an important role in the rational design of drugs. The present study has been focused on the Docking studies of 1,3-disubstituted urea...
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CORDIA MYXA POLYSACCHARIDE-G-POLY(ACRYLONITRILE) CO-POLYMER BASED MUCOADHESIVE GASTRORETENTIVE DELIVERY OF CAPTOPRIL
The objective of the present study was to prepare gum Cordia myxa-g-polyacrylonitrile using microwave irradiation and to evaluate its mucoadhesive applications. The graft co-polymerization of poly(acrylonitrile) on gum Cordia myxa was carried out employing 3- level 4-factor central composite experimental design. It was observed that the concentrations of ammonium persulphate and concentrations of ...
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STUDIES ON EVALUATION OF IN-VITRO ANTFUNGAL ACTIVITIES OF MELIA AZEDARACH L. BARK
The present investigation was attempted in order to evaluate the antifungal potential of successively extracted n-hexane and methanolic extracts of Melia azedarach L. bark. The fungi-toxic efficacy of the extracts were tested against both yeast like fungi [Candida albicans (MTCC-3017), Candida krusei, Candida tropicalis, Cryptococcus marinus (MTCC-1029)] as well as mycellial like fungi such as Asp...
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CHEMOPREVENTIVE ACTION OF EMBLICA OFFICINALIS AGAINST RADIATION AND CADMIUM INDUCED HEPATIC LESIONS IN SWISS ALBINO MICE.
In the present study an attempt has been made to explore radiation and cadmium induced histological alterations in mice liver and their modulation by Emblica officinalis fruit Extract (EOE). For this purpose mice were selected from Inbred colony and divided into five different groups. Group: Ι (Sham-irradiated group) considered as normal; II (cadmium chloride treated group) in this group animals ...
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EVALUATION OF SUB-CHRONIC TOXICITY AND HEAVY METAL TOXICITY OF KAPPAPHYCUS ALVAREZII IN- VIVO
Seaweed consumption is becoming more popular in Asian population especially the red seaweed, Kappaphycus alvarezii (K. alvarezii). However, there are few reported studies on the safety of K. alvarezii for consumption in Malaysia. This study focuses on the in vivo evaluation of toxicity and heavy metals of K. alvarezii performed in albino rats. K. alvarezii were sent for heavy metal analysis while ...
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IN-VITRO EFFECTS OF PARACETAMOL ON RHEOLOGICAL PROPERTIES OF ERYTHROCYTES AND ITS ANTIOXIDANT PROPERTIES
Human erythrocytes were pre-incubated in vitro with paracetamol and then erythrocyte’s rheological properties of deformability, osmotic fragility and aggregation were evaluated after being compromised by various means. Paracetamol (1, 2, 4mg/ml) significantly prevented the loss of deformability through 5mm diameter pores of erythrocytes dehydrated with hypertonic buffer or with calcium ionophore...
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STUDIES ON HISTOLOGICAL AND HISTOPATHOLOGICAL MYCOSIS VARIATIONS OF CHANNA STRIATUS (BLOCH) FOUND INFECTED WITH ASPERIGILLUS FUMIGATUS AND ASPERGILLUS NIGER SPP.CAUSED EUS CHARECTERSTICS.
The present investigation deals with the histological and histopathological altarations in Channa striatus infected with fungi Aspergillus fumigates and Aspergillus niger. Fresh water murrels were collected from Dharmasagar and Hasanparthy lakes and Local fish markets of Warangal district. This is due to the nature of their habitats as many native species of fish suffer from living beneath turbid ...
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PHYSICOCHEMICAL CHARACTERIZATION OF – CYCLODEXTRIN COMPLEXES OF TAMOXIFEN CITRATE AND PHASE SOLUBILITY STUDIES
The objective of the present investigation is to study the possibilities to improve the aqueous solubility and dissolution rate of Tamoxifen citrate (TC) – an oral anticancer drug, based on inclusion complexes with a– cyclodextrin (α –CD). The inclusion processes are discussed based on absorption, emission, FT-IR, 1H-NMR, SEM and phase solubility study. The α –CD study shows that the dru...
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FIRST REPORT ON EVALUATION OF ANTI-DIABETIC POTENTIAL OF CHITIN AND CHITIN-BASED DERIVATIVES AGAINST ALLOXAN INDUCED ALBINO RATS
Crustacean’s shells constitute the traditional and current commercial source of Chitin. These derivatives/molecules are potential resource as well as multiple functional substrates have generate attractive interest in various fields such as biomedical, pharmaceutical, food and environmental industries. In the present investigation, chitinous wastes were collected from the fresh water areas of De...
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