Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
RHIZOME ESSENTIAL OIL COMPOSITION OF ZINGIBER CERNUUM AND ITS ANTI MICROBIAL ACTIVITY
Zingiber cernuum belongs to family Zingiberaceae is a perennial herb, also called as Curved stem ginger. The rhizomes of Zingiber cernuum is steam distilled and the composition of essential oil was studied. The essential oil obtained was yellow in colour and the yield was about 0.007%. The chemical profile of the oil was obtained from their GC-MS analysis. The major components present in the oil a...
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SUBSTANTIATION OF THE PRESERVATIVE IN THE COMPOSITION OF THE IMMUNOBIOLOGICAL DRUG “CANDIDOCYDE”
Over the last decade the incidence of candidiasis has dramatically increased. To fight candidal infections vaccines with immune modulating properties have been actively investigating in recent years. In our previous studies it was found that the immunobiological drug under the conditional name “Candidocyde” based on the antigens of C. albicans and C. tropicalis fungi possessed the protective a...
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INHIBITION OF MYCOBACTERIAL GLYCOSYLTRANSFERASES WITH PHYTOCOMPOUNDS- AN IN-SILICO APPROACH
Emergence of Mycobacteria that are resistant to common antibiotics necessitate development of novel antibacterial drugs. The complexity of mycobacterial cell envelope plays an important role in its defense against antimicrobial activity of human immune system. The cell wall of Mycobacteria constitutes a set of carbohydrate-containing molecules. Glycosyltransferases, the glycan processing enzymes p...
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FORMULATION DEVELOPMENT AND EVALUATION OF pH TRIGGERED IN SITU OPHTHALMIC GEL OF EPINASTINE HYDROCHLORIDE
The poor bioavailability of ophthalmic solutions caused by dilution and drainage from the eye can be overcome by using in situ forming ophthalmic drug delivery system prepared from polymer that exhibit reversible liquid–gel phase transition. The objective of the study was to develop optimized formulation of in situ ophthalmic gel of Epinastine hydrochloride, an antihistaminic drug, using a p...
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ANTIMICROBIAL ACTIVITIES OF FRESHWATER CYANOBACTERIUM, NOSTOC SP. FROM TAMDIL WETLAND OF MIZORAM, INDIA: AN IDENTIFICATION OF BIOACTIVE COMPOUNDS BY GC-MS
A freshwater microalga, Nostoc sp. isolated from Tamdil Wetland of Mizoram was tested for its algicidal, antibacterial and antifungal activity. Extracts were prepared with methanol, ethanol:water and dichloromethane:isopropanol and tested for their antimicrobial activity against nine microorganisms comprising of three chlorophycean algae (Chlorella vulgaris, Scenedesmus quadricauda and Selenastrum...
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A CROSS-SECTIONAL STUDY ON ASSESSING THE KNOWLEDGE, ATTITUDE AND BEHAVIOUR OF COMMUNITY PHARMACISTS TO ADVERSE DRUG REACTIONS RELATED ASPECTS
The adverse drug reaction (ADR) programme in India, targeted all healthcare professionals to report the ADRs, however the response is very limited. The ADR reporting is much concentrated to hospital settings and the community pharmacies are unaware of this change. This study was conducted to assess the attitude, knowledge and behaviour of community pharmacists to ADR related aspects. A prospective...
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SYNTHESIS, ANTIBACTERIAL AND ANTI- MYCOBACTERIAL ACTIVITY OF SOME NOVEL3-(6-PHENYL-[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZOL-3-YL)-2H-CHROMEN-2-ONE
Several 3, 6-substituted - [1,2,4] Triazolo [3,4-b][1,3,4] Thiadiazole}-2H-Chromen-2-ones(5a-5j) have been synthesized from ethyl-2-oxo-2H-chromene-3-carboxylate (1) through a multistep reaction sequence. Compound 1 reacted with hydrazine hydrate in the presence of ethanol to give 2-oxo-2H-chromene-3-carbohydrazide (2) which on treatment with carbon disulphide and methanolic potassium hydroxide ...
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MOLECULAR DOCKING STUDIES OF SOME NOVEL HYBRID TETRAOXAQUINES & DISPIROTETRAOXANES AS ANTIMALARIAL AGENTS
In the present study, total fifteen compounds of 1,2,4,5-tetraoxane derivatives were docked. Two series of 1,2,4,5-tetraoxane derivatives were taken for molecular docking studies, one tetraoxaquines, a hybrid of two pharmacophores such as 4-aminoquinoline & 1,2,4,5-tetraoxane, and other dispirotetraoxanes. The docking studies were performed into the binding pocket of a falcipain-3 protein (pdb...
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PHARMACOKINETICS AND PHARMACODYNAMICS OF PRIMAQUINE TO PATIENTS WITH UNCOMPLICATED FALCIPARUM MALARIA IN HALMAHERA INDONESIA
Malaria remains one of deadly diseases in Indonesia which mainly occurred in Tobelo, North Halmahera. Genetic factor is one of significant factors where the gene acting in protein and enzyme coding influences the drug pharmacokinetics. However, no studies have been carried out on the pharmacokinetics of anti-malaria of primaquine in Indonesia. The purpose of this research is to know the kinetic pr...
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A CLINICAL STUDY EVALUATING THE EFFECT OF IVABRADINE ON INFLAMMATION IN PATIENTS WITH NON ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROMES
There is a strong association between elevated heart rate (HR), systemic inflammation and atherosclerosis. We assumed that HR lowering by ivabradine might decrease inflammation in patients with non ST-segment elevation acute coronary syndromes (NSTE-ACS). Objective: Study the effects of ivabradine add on treatment on High sensitivity C-reactive protein (hsCRP) levels in patients with NSTE-ACS. Met...
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