Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
INVESTIGATION OF THE BIOCHEMICAL MECHANISM OF ACTION OF ANTIOXIDANTS IN THE PREVENTION OF CANCER
The safe use of medicines is a critical issue for all health care professionals, Background: Cancer refers to a group of diseases that are associated with a disturbance in the control of cell growth and metabolism. Indeed, the unbalanced control of cellular proliferation is a primary characteristic of cancer cells and, as such, any molecule capable of inhibiting cancer cell proliferation may also ...
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ANTIHYPERGLYCEMIC ACTIVITY OF DIPTERACANTHUS PROSTRATUS NEES. AND ITS PROBABLE MECHNISM OF ACTION IN STREPTOZOTOCIN INDUCED DIABETIC RATS
The present study was aimed to investigate the antihyperglycemic effect of the Dipteracanthus prostratus nees. And it’s probable mechanism of action in Streptozotocin induced diabetes. Wistar albino rats were used to evaluate the antihyperglycemic effect of toluene (TEDP, 100 mg/kg and 200 mg/kg, body weight) and methanolic (MEDP, 100 mg/kg and 200 mg/kg, body weight) extract of D. prostratus. C...
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THERAPEUTIC POTENTIAL OF BIOACTIVE PHYTOCHEMICALS BY INHIBITING β-LACTAMASE OF MULTIDRUG RESISTANT CLINICAL ISOLATES
β-lactams have been widely used as antibiotics for treatment of nosocomial and community acquired infections for the last five decades. Under selective pressure from the extensive use of cephalosporins in 1980s and 1990s, many bacteria have emerged as resistant against these antibiotics. The resistance to β-lactam antibiotics can be due to any of the following three mechanisms i.e. decreased acc...
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FORMULATION AND COMPARATIVE STUDIES OF LOVASTATIN LOADED POLYMERIC NANOPARTICLES PREPARED BY IONIC GELATION AND SOLVENT EVAPORATION TECHNIQUE
Nanotechnology mediated drug delivery has been reported to enhance the drug efficacy, bioavailability, reduced toxicity and improve patient compliance by targeting the cells and tissues to elicit the desired pharmacological action. Low oral bioavailability of poorly water-soluble drugs poses a great challenge during development of drug delivery systems. The purpose of the present work was to com...
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PHARMACOTHERAPY OF ALZHEIMER’S DISEASE: A REVIEW
Alzheimer’s disease, the most common cause of dementia is not a normal part of aging and worsens over time. The most common early symptom of Alzheimer's is difficulty remembering newly learned information. Microscopic changes in the brain begin long before the first signs of memory loss. Two abnormal structures called plaques and tangles are prime suspects in damaging and killing nerve cells. Cu...
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NUTRIENT CONTENT OF NATIVE EARTHWORM, EUTYPHOEUS GAMMIEI (BEDDARD) OF TRIPURA (INDIA)
Eutyphoeus gammiei (Beddard) is a large native earthworm which is commonly used as fish bait and feed of chicken in Tripura. Eutyphoeus tissue comprising of both body wall and gut wall contains 63.98% protein, 15.79% carbohydrate, 7.78% fat, 1.90% crude fiber and total ash 10.55%. The result showed that essential amino acid of earthworm tissue was dominated by lysine (1.45 g /100 g), methionine (1...
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ANTI-INFLAMMATORY ACTIVITY OF TRANS-CINNAMALDEHYDE AND PIPERINE COMBINATION AGAINST CARRAGEENAN INDUCED PAW EDEMA
Inflammation is one of the unique mechanism that help body to protect itself against burn, infection, allergens, toxic chemicals, or other noxious stimuli. It is a defense reaction of the body in order to eliminate or reduce the spread of injurious agent. However, over reaction of the body may be harmful or undesirable. This has resulted in extensive development of anti-inflammatory drugs. Despite...
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DEVELOPMENT OF SPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF CEFTRIAXONE SODIUM IN DIFFERENT BRANDS OF PHARMACEUTICAL PREPARATION INVOLVING DIAZOTIZATION
A simple, precise, and robust spectrophotometric method for the determination of Ceftriaxone sodium has been investigated and validated. The proposed chemical reaction involved involves the reaction primary amine of Ceftriaxone sodium with nitrite solution in acidic medium to form a diazotized product followed by the reaction of the diazotized product with suitable coupling reagent to obtained a c...
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EVALUATION OF ANTIOXIDANT – PHYTOCHEMICAL COMPOUNDS IN PUNICA GRANATUM
The antioxidant activity of pomegranate fruit was evaluated using in vitro tests. Phenol content was more in G-137, 11.8±0.11 mg/g dry wt followed Arakta variety 10.1±0.05 mg/ g dry wt., respectively flavonol and flavonoid content was high in mrudula 3.5±0.05 mg/g dry wt, 7.0±0.05 mg/g dry wt., and proanthocyanin content was high in Bhagwa variety 19.62±0.05 mg/g dry wt, Anthocyanin conte...
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EFFECT OF ETHANOL EXTRACT FROM MORUS ALBA LEAVES SUPPLEMENTATION ON GASTRIC TISSUE GLUTATHIONE LEVEL IN INDOMETHACIN INDUCED ULCERS IN RATS
Context: The leaves Morus alba have been traditionally used in Asian countries for treatment of different ailments. Objective: Present study was undertaken to evaluate the effect of ethanol extract from Morus alba leaves supplementation on gastric tissue glutathione level in indomethacin induced ulcers in rats. Materials and Methods: Ethanol extract from Morus alba leaves were administered at the ...
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