Pages Menu
TwitterRssFacebookWhatsapplinkedin
ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

Categories Menu

Most Popular

 
Title
Views
PDF
Cited
26.

IMPACT OF ALCOHOL ON RAT HEART AND AORTIC TISSUE ACETYLCHOLINE CONTENT LEVELS IN VITRO AND IN VIVO

Acetylcholine satisfies all criteria for a transmitter substance. Its most widely recognized action sites are the endings of vertebrate motor nerves, the endings of the automatic pre ganglionics and the parasympathetic post ganglionics. It appears also to be the transmitter of motor nerves in all advanced invertebrate animals except the arthropods where it seems to separate at the endings of senso...

M. Yugandhar*, M. Rajeswara Rao

Department of Zoology, S.V. University, Tirupati – 517502, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(3).892-95

892-895

4300

1471

7.

MELATONIN: A NOVEL BIOMATERIAL FOR IMMUNOTHERAPY

The mainly deliberate endocrine product of the pineal gland, melatonin, has been reported to be involved in the feedback between neuroendocrine and immune functions and to exert oncostatic action, at least in certain experimental conditions. Melatonin seems to be a vital part of the immune system, by exerting direct and/or indirect stimulatory effects on both cellular and humoral immunity. Likewis...

Vaibhav D. Aher* and Arun Kumar Wahi

Institute of Pharmacy, NIMS University, Jaipur, Rajasthan, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(4).772-77

772-777

4300

1595

9.

HEMICELLULASE – MEDIATED HYDROLYSIS OF CHITOSAN: AN EFFICIENT METHOD TO SYNTHESIZE WATER SOLUBLE CHITOSAN

Chitosan is a natural biopolymer that has been extensively used traditionally for the treatment of various ailments and as an efficient vehicle or carrier for fabrication, encapsulation and target-specific delivery of a wide range of pharmacological moieties for improved therapeutic efficacy. Despite of numerous characteristic features, the pharmaceutical significance of chitosan is limited due to...

Z. Hussain, S. Sahudin*, I. N. M. Haliza, M. Hussain, M. L. M. Sabri and M. A. Ismail

Department of Pharmaceutics, Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, Bandar Puncak Alam, Selangor, Malaysia.

DOI: 10.13040/IJPSR.0975-8232.9(1).80-87

80-87

4300

1958

31.

DUAL WAVELENGTH SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF PARACETAMOL AND PIROXICAM IN THEIR COMBINED TABLET DOSAGE FORM

A simple, accurate, and precise dual-wavelength spectrophotometric method was developed to determine Paracetamol and Piroxicam in combined pharmaceutical dosage form simultaneously. The principle for the dual wavelength method is “the absorbance difference between two points on the mixture spectra is directly proportional to the concentration of the component of interest”. The pre‐requisite ...

Kinjal Parmar * and Shreyas Patel

Department of Quality Assurance, Parul Institute of Pharmacy and Research, Parul University, Post Limda, Waghodia, Vadodara, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.14(3).1339-43

1339-1343

4300

1691

70.

A CLINICAL COMPARATIVE STUDY OF PROPHYLACTIC INFUSIONS OF PHENYLEPHRINE AND EPHEDRINE ON MATERNAL HEMODYNAMICS AND FETAL ACIDOSIS IN ELECTIVE CAESAREAN SECTION

Introduction: This randomized double blind study was started with an objective of comparing two commonly used vasopressors – ephedrine and phenylephrine in infusion form  with crystalloid co-hydration to reduce spinal anesthesia induced hypotension in elective caesarean section. Methods: One hundred patients were randomized into two groups to receive either 100 μg/ml phenylephrine (group-P,...

Urvashi Yadav* and Kunwar Bharat

M.D. Anaesthesiology, Type 3, E/1 Block, New Campus, U.P. Rural Institute of Medical Sciences and Research, Saifai, Etawah, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(12).5056-61

5056-5061

4299

2216

20.

BIOCHEMICAL EVALUATION OF ANTIDIABETIC AND ANTIOXIDANT POTENTIALS OF ANNONA SQUAMOSA LEAVES EXTRACTS STUDIED IN STZ INDUCED DIABETIC RATS

Diabetes mellitus is characterized by persistent fasting and postprandial blood glucose levels due to inability of the body cells to utilize glucose properly. Though drugs are plenty for the treatment of diabetes, none is found to be ideal due to undesirable side effects and diminution after prolonged use. Hence, search for novel drugs, especially from plant origin continues. Based on folkloric us...

S. K. Hayath Basha and S. Subramanian*

Department of Biochemistry, University of Madras, Guindy campus, Chennai, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(3).643-55

643-655

4299

1826

46.

EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF MORUS INDICA LINN. AGAINST TOXICITY INDUCED BY CARBON TETRACHLORIDE IN RATS

Morus indica- MI-S36 is a potential source of phytochemicals and is well explored for its medicinal properties such as antidiabetic and antioxidant activity. In the present study, Mous indica aqueous (MAq) and dechlorophyllised (MDc) extracts efficacy to protect against the carbon tetrachloride (CCl4) induced hepatotoxicity was studied in rats in comparison with standard drug Liv52. The experiment...

Vanitha Reddy P. * and Asna Urooj

DOS in Food Science and Nutrition, University of Mysore, Mysore, India

DOI: 10.13040/IJPSR.0975-8232.8(2).845-51

845-851

4299

1668

22.

NEURO-PROTECTIVE PROPERTIES OF ORTHOSIPHON STAMINUS (BENTH) LEAF METHANOLIC FRACTION THROUGH ANTIOXIDANT MECHANISMS ON SH-SY5Y CELLS: AN IN-VITRO EVALUATION

In present study to evaluate the mechanisms behind the antioxidant and neuro-protective potential of Orthosiphon staminus methanol bio active guided fraction (OMF) using SH-SY5Y human neuroblastoma cell culture model was carried out. In in-vitro studies, mechanisms of neutralization of H2O2 induced toxicity by OMF using MTT, LDH, ROS, MMP, MDA, Comet assay was performed. Regulation of anti-oxidant...

N. Vijaya Sree *, P. Udaya Sri and N. Ramarao

Department of Biotechnology, Acharya Nagarjuna University, Guntur, Andhra Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.6(3).1115-25

1115-1125

4298

1979

47.

CHARACTERIZATION OF BACTERIOCIN FROM PROBIOTIC LACTOBACILLUS PLANTARUM

In our study, the sample (cheese) was selected for isolation and identification of Lactobacillus species as local probiotic isolate. The strain was subjected to microscopic and macroscopic investigations for probiotic selection. The world health organization criteria (WHO) were applied to all Lactobacillus species against E. coli, P. areoginosa, S. aerus, Chromobacterium, Serratia and A. flavus, a...

A. Jayachitra*, C.M. Sukanya and N. Krithiga

Department of Plant Bio-technology, School of Biotechnology, Madurai Kamaraj University 1, Madurai- 6250021, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(11).4374-86

4374-4386

4298

1619

12.

IDENTIFICATION OF POTENT VIRTUAL LEADS AS TOPOISOMERASE-II INHIBITORS USING PHARMACOPHORE MODELLING, MOLECULAR DOCKING AND ADME STUDIES

Topoisomerase enzymes are highly expressed in cells which undergo rapid multiplication. Inhibition of this enzyme represents a potential therapeutic approach for diseases such as cancer. In order to understand the structure activity correlation of 2, 4, 6 pyridine based topoisomerase inhibitor, we have carried out a combined pharmacophore modelling, 3D-QSAR studies, molecular docking and virtual s...

Sanal Dev and Sunil R. Dhaneshwar*

Faculty of pharmacy- university of Aleppo. Department of analytical and food chemistry, Syria

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(8).2939-54

2939-2954

4298

1958