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ANTIDIABETIC ACTIVITY OF BERBERIS ASIATICA (D.C.) ROOTS
Barberries are a large group of evergreen shrubs, found in Lalitpur, Allahabad, Bhopal and Haldwani etc. It is an evergreen shrub. Commonly, its fruits are called as berries. This plant is generally use in case of diabetes and mouth ulcer, as a traditional use. Type 2 diabetes mellitus (formerly called NIDDM, type II or adult-onset) is characterized by insulin resistance in peripheral tissue and a...
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MICROBIAL CONCRETE: THE PIONEERING WORK ON REPAIRING CONCRETE
The global demand of concrete is increasing every year and generally is considered as most consumed material on earth. But concrete is vulnerable to deterioration, corrosion, and cracks, and the consequent damage and loss of strength requires immensely expensive remediation and repair. One such mechanism that receives increasing attention in recent years is the ability for self-repair. So a nove...
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1567
NEWER VACCINE INTRODUCTION (PNEUMOCOCCAL CONJUGATE VACCINE) FROM THE STATE’S OWN RESOURCES IN HARYANA, INDIA: AN EXAMPLE OF ADVOCACY TO POLICY AND ACCELERATED PUBLIC HEALTH ACTION
Introduction: Global pneumonia mortality (50%) caused by pneumococcus is responsible for invasive pneumococcal disease. Pneumococcal Conjugate Vaccine (PCV) has been introduced by the Government of India in a phased manner in selected states, but Haryana was not included. Objective: To draw key lessons learned from the process of newer vaccine introduction (PCV) in Haryana from the state’s resou...
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SYNTHESIS, CHARACTERIZATION OF SOME 2-AZETIDINONE DERIVATIVES FROM 4- NITRO ETHYL BENZOATE BY MICROWAVE METHOD AND EVALUATION OF THEIR ANTIMICROBIAL ACTIVITY
Non classical, High-speed, environmentally benign synthesis with microwaves has attracted researchers for organic synthesis a considerable amount of attention in recent years. An expeditious one pot microwave irradiation method for preparation of 2-azetidinones is developed. This method has been assessed as greener methodology. In our present study, series of five novel azetidinones are synthesi...
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4521
NOCTURNAL ENURESIS, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF PANDANUS ODORATISSIMUS L. PEDUNCLE
Nocturnal Enuresis treatment activity in rabbits by measuring the changes in urine volume and concentrations of electrolytes as well as bladder capacities. In addition, antioxidant activity was measured using free radical scavenging (DPPH method) and antimicrobial activity against human bacterial pathogens using agar diffusion technique. Pandanus Odoratissimus L. peduncle showed no toxic effect wi...
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2038
COMBINATION THERAPY AND ITS IMPLICATION ON CLINICAL EFFICACY OF ARTEMISININS- REVIEW
Artemisinin and its derivatives have successfully been used in treatment of falciparum malaria infections in various parts of the world. More importantly, they have proved effective against strains resistant to conventional antimalarials such as chloroquine and mefloquine in those parts of the world where malaria is endemic. Only one clinically relevant artemisinin-resistant human malaria has been...
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BIOASSAY GUIDED FRACTIONATION OF SPHAERANTHUS INDICUS EXTRACT AGAINST MOSQUITO VECTORS
Phytochemicals with mosquitocidal potential are now recognized as potent alternative insecticides. This study aims at exploring the mosquitocidal potential of the extract of the medicinal plant Sphaeranthus indicus. The soxhlet extracts of flowers, leaves and aerial parts of S. indicus with four solvents viz., hexane, chloroform, ethyl acetate, and methanol were screened against the larvae of the ...
4232
1982
DESIGN AND EVALUATION OF BILAYERED MUCOADHESIVE FILM OF CEFPODOXIME PROXETIL
The objective of the present work was to formulate and evaluate a sustained release gastroretentive dosage form. A mucoadhesive bilayered film was prepared consisting of an Immediate Release (IR) and a Controlled Release (CR) layer. The film is folded into a Hard Gelatin Capsule which after administration into GIT unfolds and adheres to the GI mucosa. Cefpodoxime Proxetil is an antibiotic of BCS C...
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1803
IMPROVED EFFICIENCY AND REDUCED COSTS DURING INFUSION THERAPY WITH PREMIXED PREPARATIONS COMPARED TO FREEZE-DRYING POWDER
Background: An excessive medical expenditure is becoming a main barrier to good health for several people in China. Hence, there is a need to control this rising medical cost to reduce the financial burden placed on family and society in general. Objective: Our aim was to understand the expenses incurred during the use of two forms of infusion therapy- the premixed preparations and the freeze-d...
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1598
PHARMACOLOGICAL AND PHYTOCHEMICAL EVALUATION OF ANTI-ULCEROGENIC POTENTIAL OF SOLANUM NIGRUM
Anti-ulcer activity of the Solanum nigrum L. extracts was studied in rats by using pylorus ligated ulcer model. Rantidine was used as the standard drug for comparison. The animals were sacrificed after 19 hrs after the ligation. Stomach was dissected out and contents were drained into tubes and were centrifuged at 1000 rpm for 10min and volume was noted. The PH of gastric juice was recorde...
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