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PHENOLIC ACIDS AND FREE RADICAL SCAVENGING ACTIVITY OF ALCHEMILLA JUMRUKCZALICA PAWL
Comparative study of free radical scavenging activity and phenolic acid content of Bulgarian endemic Alchemilla jumrukczalica and the commercial herbal - Alchemilla vulgaris complex was carried.The methanol extracts of studied samples showed significant antiradical activity. The concentration of the extracts needed for 50% inhibition of DPPH was found to be 12,09 µg/ml and 19,62 µg/ml for A. jum...
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SYNTHESIS OF NOVEL 1, 3-INDANEDIONE DERIVATIVES AND PHARMACOLOGICAL EVALUATION AS ANTI-MICROBIAL, ANTI-OXIDATIVE AGENTS
1,3-Indanedione derivatives, which are of wide interest because of their diverse biological and chemical applications. A series of novel 1,3-Indanedione derivatives are synthesized via KNOEVENAGEL condensing reaction mechanism by condensing 1,3-Indanedione with the 1-(4-aminophenyl) ethanone to form a styrylated indanedione leading to the formation of different Schiff base (imine) preparation by u...
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NUCLEAR MAGNETIC RESONANCE AND HYPHENATIONS – A REVIEW
Nuclear magnetic resonance spectroscopy is an absorption spectroscopic technique that helps in structural elucidation and has a wide range of applications in various fields like drug discovery and development, metabolomics, combinatorial chemistry, and food sciences. This paper gives information about nuclear magnetic resonance spectroscopy, and clear description of LC-NMR-MS, and a brief descript...
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THE EFFECT OF ELICITORS ON THE PRODUCTION OF VASICINE FROM JUSTICIA ADHATODA L. CELL SUSPENSION CULTURES
In this study, α-naphthyl acetic acid and mannitol were used as elicitors to improve the productivity of useful metabolite, vasicine for archiving high concentration in Justicia adhatoda L. cell suspension cultures. When the cells were treated with 3mg 100 ml-1 suspension of α-naphthyl acetic acid, the vasicine concentration was increased by 1.65 mg ml-1 in 15 days culture compared to untrea...
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EVALUATION OF ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF DROSERA SPATULATA
The aim of the present study is to investigate and evaluate analgesic and anti-inflammatory potential of aqueous and methanolic extracts of Drosera spatulata using different models in rats. The aqueous and methanolic extracts of D. spatulata (at the doses of 3, 4, 5, 8 and 10 mg/Kg body weight) investigated for anti-inflammatory and analgesic activities using various experimental models. Analgesic...
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CHARACTERIZATION OF BACTERIOCIN FROM PROBIOTIC LACTOBACILLUS PLANTARUM
In our study, the sample (cheese) was selected for isolation and identification of Lactobacillus species as local probiotic isolate. The strain was subjected to microscopic and macroscopic investigations for probiotic selection. The world health organization criteria (WHO) were applied to all Lactobacillus species against E. coli, P. areoginosa, S. aerus, Chromobacterium, Serratia and A. flavus, a...
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ANTIMICROBIAL ACTIVITY OF STEM BARK OF COMBRETUM ALBIDUM G. DON; A TRADITIONAL MEDICINAL LIANA
Traditional knowledge and ethno-botanical use of plants have been widely acknowledged all over the world. In the present scenario, emergence of multiple drug resistance to human pathogenic organisms, this has necessitated a search for new antimicrobial substances from other sources including plants. Combretum albidum, a traditional medicinal liana, used by rural peoples, villagers and tribals resi...
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PHYTOCONSTITUENTS OF SPILANTHES OLERACEA LINN. SHOOT: A MEDICINAL FOOD HERB USED AMONG TRIBAL PEOPLE OF ARUNCHAL PRADESH, INDIA
Herb is an indispensable food ingredient for the tribal people of Arunachal Pradesh. They practices innumerable traditional food recipe to maintain good health. Spilenthes oleracea L. is one of such medicinal food plant used by tribal people of Arunachal Pradesh. The study was carried out to find out the phytoconstituents of S. oleracea shoot. Ethanolic extract of the sample was subjected to GC-MS...
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ISOLATION OF EPICATECHIN FROM OXYSTELMA ESCULENTUM
Background: Oxystelma esculentum is used traditionally as diuretic, laxative, hepatoprotective and anti-ulcer. Objectives: The present work deals with the isolation and structure elucidation of Epicatechin from O. esculentum. Methods: Methanolic extract of the entire plant of O. esculentum was subjected to pilot TLC experiments and column chromatography. Results: This yielded a pure, whit...
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HYPER ACCUMULATION OF CADMIUM IN SOLANUM NIGRUM L. AND THEIR EFFECTS ON PHYTO-CHEMICALS AND ANTIOXIDANT ENZYMATIC ACTIVITIES
In the pot experiment, Solanum nigrum L. treated with different concentration of Cd showed high accumulation of Cd in plant. Growth of plant was not significantly affected up to ≤ 50ppm Cd treated plant, The trends of Cd accumulation in plant were leaf>shoot>root with increasing concentration of Cd and DAS. Plant accumulates 298, 92 and 58 ppm of Cd after 60DAS in leaf>shoot>root re...
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