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PROSPECTIVE SURVEY STUDY ON ASSESSMENT AND EDUCATION OF HOME MEDICINE CABINET IN GENERAL POPULATION OF COMMUNITY
Objective: To assess and educate about home medicine cabinet among randomly selected houses of people in community of Greater Noida city & to carry out the survey of medicines proper storage, safe use, list of total and expired drugs, their disposal and maintenance of home medicine cabinets. Method: This study was a simple randomised prospective survey study. This prospective study was carr...
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A VALIDATED HPLC METHOD FOR ESTIMATION OF LORN AND PCM IN THEIR COMBINED TABLET DOSAGE FORM
The present work describes a reverse phase high performance liquid chromatographic method without use of buffer in mobile phase for the simultaneous estimation of Lornoxicam and Paracetamol in combined tablet dosage form. Chromatography was performed on Chromasil C18 (250 × 4.6 mm i.d. and particle size 5 μm) column in isocratic mode with mobile phase containing acetonitrile: 0.2% triethylamine ...
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HAEMATOLOGICAL AMELIORATION BY ZIZYPHUS MAURITIANA IN SILICA INDUCED TOXICITY IN WISTAR ALBINO RATS
This study was aimed to investigate the biochemical influence of aqueous extracts of roots, stem and leaves of Zizyphus mauritiana (ZM) on silica induced toxicity in rats, with changes in inflammatory markers in liver and kidney. To test the preventive effect of extracts of Zizyphus mauritiana on development of silica induced toxicity in wistar albino rats, animals were treated simultaneously with...
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SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND EVALUATION OF ANTI-TUMOR PROPERTIES OF NOVEL FATTYACID CONJUGATES OF 2, 4 AND 2, 6-DIISOPROPYLPHENOL
The present study enumerates the synthesis, spectroscopic characterization, and evaluation of antitumor properties of esters of two fatty acids viz., 5-hexenoic acid and iso- ricinoleic acid with 2, 4- or 2, 6-diisopropylphenol (Propofol). Propofol is a potent intravenous hypnotic agent which is widely used for the induction and maintenance of anesthesia and for sedation in the intensive care unit...
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STUDY THE ANTIBIOTIC RESISTANCE PATTERN IN A TERTIARY CARE TEACHING HOSPITAL
Introduction: Antibiotics suppress the growth of or kill another microorganism at very low concentrations. Therefore this is the one of the supreme invention need of this era. Most bacteria are becoming resistant to various antibiotics, make a limitation for treating minor and major infectious. Hence, determining the resistance patterns in the geographical area will help in choosing and use of the...
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SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME NOVEL SEMICARBAZONE DERIVATIVES CONTAINING QUINOXALINE MOIETY
Various 1-(substituted benzylidene)-5-(3-hydroxyquinoxaline-2-yl) carbonohydrazide were synthesized starting from orthophenylenediamine. Structures of all the compounds were confirmed on the basis of spectral analyses. All the newly synthesized compounds were screened for anticonvulsant activity. Some of the compounds showed significant anticonvulsant activity with no neurotoxicity....
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NUTRITION STATUS AND MAJOR RISK FACTORS OF HYPERTENSION AMONG ADULTS IN TIGRAY, NORTH ETHIOPIA; A CASE CONTROL STUDY
Introduction: - The nutritionalstatusand health outcome of older persons in low-income countries including Ethiopia is inadequately documented. Logistical difficulties and the absence of simple, easy-to-handle assessment instruments and data-collection problems in this environment are evident. As a result, nutritional data for older adults are inadequate. The scanty, mainly hospital-based, data th...
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SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW 3, 4- DIHYDROPYRIMIDINONES
A number of aldehydes were reacted with acetyl acetone or ethyl acetoacetate and urea under Biginelli reaction conditions to give the corresponding 5-acyl-4-(substituted-aryl)-6-methyl-3,4-dihydropyrimidin-2-one. The 5-acetyl-derivatives were converted into pyrimido-oxazoles, pyrimido-pyrazoles, and chalcones. Some Mannich bases were also synthesized. Some selected compounds were tested for their ...
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FORMULATION AND IN-VITRO EVALUATION OF CONTROLLED RELEASE FLOATING TABLETS OF LAMIVUDINE
The aim of the present work is to increase the gastric residence time of Lamivudine by preparing it into gastro retentive floating tablets whereby making it available at its site of absorption and to achieve an extended action for a time period of 24hrs and to reduce the dosing frequency to once a day, using release retardant polymers METHOCEL, POLYOX and CARBOPOL. The compatibility of the drug wi...
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BIOCHEMICAL CHARACTERISATION OF PHOSPHO BACTERIUM ISOLATED FROM RHIZOSPHERE OF COSTUS SP. WITH SPECIAL REFERENCE TO BACILLUS SPECIES
Soils generally contain adequate amount of inorganic and organic phosphorous but most of these remain unavailable to plants. The efficiency of water soluble phosphorus alone is usually low and soluble phosphorus when added to soil along with phosphate solubilizing microorganisms indicates utilization. The presence of soil microorganisms capable of transforming insoluble phosphorus to soluble form ...
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