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A RANDOMIZED CLINICAL TRIAL TO ASSESS AND COMPARE THE ANTIMICROBIAL ACTIVITY OF PLANTS OF LYTHRACEAE FAMILY WITH HIORA MOUTH WASHES IN SUBJECTS WITH CHRONIC PERIODONTITIS – “UNVEILING THE UNSEEN EFFECTS”
Aims and objectives: Periodontal disease is the most common disease associated with microbial infection with destruction of supporting structures. The aim of the present study is compare the antimicrobial efficacy of plants of lythraceae family with hiora mouthwash in subjects with chronic periodontitis. Materials and methods: A total of 90 subjects were taken and randomly divided into three group...
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FORMULATION AND IN-VITRO EVALUATION OF CONTROLLED RELEASE FLOATING TABLETS OF LAMIVUDINE
The aim of the present work is to increase the gastric residence time of Lamivudine by preparing it into gastro retentive floating tablets whereby making it available at its site of absorption and to achieve an extended action for a time period of 24hrs and to reduce the dosing frequency to once a day, using release retardant polymers METHOCEL, POLYOX and CARBOPOL. The compatibility of the drug wi...
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NUTRITION STATUS AND MAJOR RISK FACTORS OF HYPERTENSION AMONG ADULTS IN TIGRAY, NORTH ETHIOPIA; A CASE CONTROL STUDY
Introduction: - The nutritionalstatusand health outcome of older persons in low-income countries including Ethiopia is inadequately documented. Logistical difficulties and the absence of simple, easy-to-handle assessment instruments and data-collection problems in this environment are evident. As a result, nutritional data for older adults are inadequate. The scanty, mainly hospital-based, data th...
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ENDOPHYTIC FUNGI FROM MANGROVES – REVIEW
Mangrove plants are used in medicines, and extracts from mangrove species have proven inhibitory activity against human, animal, and plant pathogens. Endophytic fungi are an important component, are universal, and occur within all know plants, including a broad range of hosts in various ecosystems, and therefore play an important role in the natural environment. Numerous species of mangrove produc...
4112
1951
NEEM LEAF EXTRACT PREVENTS METHOTREXATE INDUCED GENOTOXICITY IN THE SOMATIC CELLS OF DROSOPHILA MELANOGASTER”
Background &Objective: To explore possible protective effect of neem leaf extract against methotrexate induced genotoxicity in the somatic cells (wing primordial) of Drosophila melanogaster. Methods: In the first phase of the experiment, neem leaf extract (NLE) at two doses was tested in the somatic cells (wing primordia) of Drosophila melanogaster (3rd instar trans heterozygous larvae resu...
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SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME NOVEL SEMICARBAZONE DERIVATIVES CONTAINING QUINOXALINE MOIETY
Various 1-(substituted benzylidene)-5-(3-hydroxyquinoxaline-2-yl) carbonohydrazide were synthesized starting from orthophenylenediamine. Structures of all the compounds were confirmed on the basis of spectral analyses. All the newly synthesized compounds were screened for anticonvulsant activity. Some of the compounds showed significant anticonvulsant activity with no neurotoxicity....
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ANATOMICAL AND HISTOCHEMICAL CHARACTERISTICS OF MORINDA CITRIFOLIA L. (RUBIACEAE)
Morinda citrifolia (L.) is an important medicinal plant belonging to the family Rubiaceae and commonly known as “Noni” in Tamil was highly distributed in South India. The aim of this research is to understand the concept and techniques of anatomical and histochemical localization of secondary metabolites in Morinda citrifolia (L.) as well as take part in the standardization of herbal medicine....
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GLIAL CELLS RESPONSES: IN OPIOID WITHDRAWAL SYNDROME
Drug addiction represents one of the major medical, social, and economic burdens of human behavior. Opioids are powerful relievers; use of opioids for the treatment of pain has been associated with the potential disadvantages including development of tolerance, dependence. There are seven stages involved in opioid addiction. Identification of glial-mediated mechanism inducing opioid side effects i...
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IN VITRO ANTIOXIDANT SCREENING OF BIO-ACTIVE FRACTION OF SEEDS OF STRYCHNOS POTATORUM LINN
Strychnos potatorum Linn. is a medium sized deciduous tree belonging to the family Loganiaceae. The collected seeds of Strychnos potatorum were dried and powdered. Methanolic extract of these seeds was prepared by cold maceration. The preliminary phytochemical screening of the crude extract revealed the presence of flavonoids and phenolic compounds. The crude extract was partitioned (gradient) wit...
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1848
EXTRACTION AND PHYTOCHEMICAL SCREENING OF MIKANIA SCANDENS LINN. AND EVALUATION OF ITS METHANOLIC EXTRACT FOR ANALGESIC ACTIVITY
Mikania scandens is a rapidly growing herbaceous to semi-woody, perennial vine. It grows quickly over other plants such as young trees, smothering them; it can climb trees up to 25 m tall. Although not as serious a weed as M. chordate, in Southeast Asia it has become a hard to eradicate weed of tea, rubber, and other plantation crops. It also reduces the carrying capacity of pasture. The achenes a...
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