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DISPERSIBLE FORMULATION MAKEUPS FOR PEDIATRIC USE: A REVIEW
Childhood is characterized by periods of rapid growth, maturation, and development. There is a change in the magnitude of the dose required during childhood and adolescence. Thus, Paediatric practice requires a range of dosage forms that are acceptable at different ages and abilities and a range of strengths or concentrations allowing administration of the correct age-related dose. Literature show...
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ISOLATION AND PURIFICATION OF NIMBIDIN FROM AZADIRACHTA INDICA OF WESTERN GHATS AND EVALUATE ITS ANTIOXIDANT, ANTI-BACTERIAL AND ANTI-DIABETIC PROPERTIES
Azadirachta Indica has always been known to be the bestowed with good health for many centuries in India. It has been found that the Neem is native to Asian countries. There are three major active components in A. indica, namely nimbin, nimbidin, and nimbiene. The compound nimbidin was isolated by chromatographic techniques. A. indica leaves extract was prepared, and the phytochemical analysis was...
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QUANTITATIVE ESTIMATION OF DRUGS AND PHARMACEUTICALS USING CHLORAMINE-T AND SAFRANIN-O DYE BY AN OXIDATIVE SPECTROPHOTOMETRIC METHOD
Simple, sensitive and selective methods are developed for the spectrophotometric determination of drugs, viz., Cetirizine hydrochloride, Duloxetine hydrochloride, Esmolol hydrochloride, Gemifloxacin, Moxifloxacin and Phenylephrine Hydrochloride based on their reactivity towards Chloramine-T (ChL-T). The method is based on the oxidation of drugs by ChL-T (Excess amount) in presence of acidic medium...
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1796
BUCCAL MIDAZOLAM: COULD IT BE AN ALTERNATIVE FOR I/V DIAZEPAM FOR ACUTE SEIZURES IN MALNOURISHED CHILDREN
Acute convulsive disorders are the most frequent neurological disorders in children which require emergency drug treatment. Immediate management of a convulsive episode is must as, delay can lead to status epilepticus, which is a significant cause of neurological morbidity and mortality among children. Benzodiazepines especially diazepam is often used as first line and routinely administered intra...
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DEVELOPMENT AND EVALUATION OF TASTE MASKED ORODISPERSIBLE TABLET OF OFLOXACIN
Ofloxacin is an antibacterial agent used to treat infections. It is extremely bitter in taste and taste should be masked to formulate it in a palatable form. The purpose of present research work was to formulate tasteless complexes of ofloxacin with indion 204 ion exchange resin. The drug loading onto ion-exchange resin was optimized for mixing time, activat...
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ANTIPLASMODIAL ACTIVITY OF EXTRACTS OF KHAYA SENEGALENSIS (DERS.) A. JUS (MELIACEAE) AND MELIA AZEDARACH L., PLANTS OF SENEGALESE TRADITIONAL MEDICINE
Two medicinal plants (Khaya senegalensis and Melia azedarach), frequently used by a large part of the Senegalese population and in particular that of the natural region of Casamance in the traditional treatment of malaria, were selected to study phytochemistry and to compare the antimalarial activity of the different parts used (leaves, bark, and seeds). The extraction of these drugs was carried o...
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PROSPECTIVE SURVEY STUDY ON ASSESSMENT AND EDUCATION OF HOME MEDICINE CABINET IN GENERAL POPULATION OF COMMUNITY
Objective: To assess and educate about home medicine cabinet among randomly selected houses of people in community of Greater Noida city & to carry out the survey of medicines proper storage, safe use, list of total and expired drugs, their disposal and maintenance of home medicine cabinets. Method: This study was a simple randomised prospective survey study. This prospective study was carr...
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SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND EVALUATION OF ANTI-TUMOR PROPERTIES OF NOVEL FATTYACID CONJUGATES OF 2, 4 AND 2, 6-DIISOPROPYLPHENOL
The present study enumerates the synthesis, spectroscopic characterization, and evaluation of antitumor properties of esters of two fatty acids viz., 5-hexenoic acid and iso- ricinoleic acid with 2, 4- or 2, 6-diisopropylphenol (Propofol). Propofol is a potent intravenous hypnotic agent which is widely used for the induction and maintenance of anesthesia and for sedation in the intensive care unit...
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CYTOTOXIC ACTIVITY OF N-HEXANE, CHLOROFORM AND CARBON TETRACHLORIDE FRACTIONS OF THE ETHANOLIC EXTRACT OF LEAVES AND STEMS OF BACCAUREA RAMIFLORA (LOUR.).
The purpose of the study was to find out the cytotoxic activity of the n-hexane, chloroform and carbon tetrachloride fractions of the ethanolic extracts of the leaves and stems of Baccaurea ramiflora (Lour.). Ethanolic extracts of the leaves and stems of Baccaurea ramiflora were subjected to solvent-solvent partitioning using n-hexane, chloroform and carbon tetrachloride to obtain n-hexane leaves ...
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1797
HAEMATOLOGICAL AMELIORATION BY ZIZYPHUS MAURITIANA IN SILICA INDUCED TOXICITY IN WISTAR ALBINO RATS
This study was aimed to investigate the biochemical influence of aqueous extracts of roots, stem and leaves of Zizyphus mauritiana (ZM) on silica induced toxicity in rats, with changes in inflammatory markers in liver and kidney. To test the preventive effect of extracts of Zizyphus mauritiana on development of silica induced toxicity in wistar albino rats, animals were treated simultaneously with...
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