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NUTRACEUTICALS: A SLOW TRANSITION FROM PREVENTIVE TO CURATIVE HEALTHCARE AND THE PERCEPTIONS AMONG PHYSICIANS AND PATIENTS – A STUDY OF SOUTH DELHI IN INDIA
Introduction: The health and wellness sector is bracing for a radical change with Information and Communication Technology taking the leading role in research and development, diagnostics, and monitoring. The consumer’s focus is shifting from treatment-based remedies to preventive remedies gradually. Aim: To explore the slow transition from curative to preventive healthcare in the prescribing be...
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BRASSICA OLERACEA: A POTENT ANTIOXIDANT THERAPEUTIC IN HEALTH AND DISEASES
Oxidative stress contributes towards initiation and progression of hepatic damage in a variety of liver disorders (e.g. Hepatitis C, Hepatitis B, non alcoholic fatty liver disease amongst others). Hence, there is a great demand for the development of agents with potent antioxidant effect. There are various plant derived products which act as antioxidants. The aim of the present investigation is to...
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1665
DEVELOPMENT AND VALIDATION OF SECOND ORDER DERIVATIVE SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF ATENOLOL AND NIFEDIPINE IN COMBINED DOSAGE FORM
A simple, precise, accurate and reproducible spectrophotometric method has been developed for Simultaneous estimation of Atenolol and Nifedipine by employing second order UV derivative Spectrophotometric method in Water: ACN (60:40). The Second order derivative absorption at 245.63 nm (zero cross point of Nifedipine) was used for quantification of Atenolol and 218.7 nm (zero cross point of Atenolo...
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DEVELOPMENT AND EVALUATION OF PUSH-PULL BASED OSMOTIC DELIVERY SYSTEM FOR ROPINIROLE
Ropinirole hydrochloride is indicated in Parkinson’s disease and Restless leg syndrome. In advanced Parkinson’s disease the usual dose of Ropinirole hydrochloride is 0.25 to 5 mg three to four times a day. Hence, an attempt was made to develop a once-a-day controlled release Osmotic drug delivery system. This may offer significant patient benefits by providing enhanced efficacy and reduced sid...
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1784
NEUROPROTECTIVE ROLE OF HERB ECLIPTA ALBA LINN. ON ACUTE AND CHRONIC UNPREDICTABLE STRESS INDUCED BEHAVIORAL, BIOCHEMICAL AND NEURO-TRANSMITTER ALTERATION IN WISTAR MALE ALBINO RAT BRAIN
Chronic stress is a risk factor for the development of many psychopathological conditions in humans, including major depression and anxiety disorders and cognitive dysfunction. It is therefore important to focus on identifying possible mechanism to prevent these stress-induced disorders. Therefore, current study was designed to investigate the effect of Eclipta alba on chronic unpredicted stress (...
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1807
PREPARATION AND EVALUATION OF ISONIAZIDE NANO-CONJUGATES FOR IMPROVING THE THERAPEUTIC EFFICIENCY
Raise in the multidrug resistance gave challenge to the treatment of tuberculosis with first line medication due to less response. Nanoparticle drug delivery has proven efficiency in improving the therapeutic efficacy of many drugs. Reduction of dosing frequency was achieved by applying drug delivery using Nano medicine and Green Nanotechnology. The present study aimed in the production of such dr...
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CLINICAL EVALUATION OF T-AYU-HMTM IN THE MANAGEMENT OF SICKLE CELL ANEMIA
Sickle cell anemia is a hemoglobin disorder, which is an autosomal recessive type affects millions of children of underprivileged and tribal area every year. Because of its devastating complications sickle cell is considered a major health problem in India and the entire world. Since many years, majority of the tribal population in the South Gujarat region are suffering from this lifelong disorder...
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DISPERSIBLE FORMULATION MAKEUPS FOR PEDIATRIC USE: A REVIEW
Childhood is characterized by periods of rapid growth, maturation, and development. There is a change in the magnitude of the dose required during childhood and adolescence. Thus, Paediatric practice requires a range of dosage forms that are acceptable at different ages and abilities and a range of strengths or concentrations allowing administration of the correct age-related dose. Literature show...
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QUANTITATIVE ESTIMATION OF DRUGS AND PHARMACEUTICALS USING CHLORAMINE-T AND SAFRANIN-O DYE BY AN OXIDATIVE SPECTROPHOTOMETRIC METHOD
Simple, sensitive and selective methods are developed for the spectrophotometric determination of drugs, viz., Cetirizine hydrochloride, Duloxetine hydrochloride, Esmolol hydrochloride, Gemifloxacin, Moxifloxacin and Phenylephrine Hydrochloride based on their reactivity towards Chloramine-T (ChL-T). The method is based on the oxidation of drugs by ChL-T (Excess amount) in presence of acidic medium...
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ANTIDIABETIC AND HYPOLIPIDEMIC EFFECTS OF METHANOLIC EXTRACT OF FILICIUM DECIPIENS IN STREPTOZOTOCIN INDUCED DIABETIC RATS
This study evaluated methanolic extract of Filicium decipiens (MFD) on reducing hyperglycemia and hyperlipidemia in streptozotocin-induced diabetic rats. MFD was orally administered once a day after 3 days of streptozotocin -induction at 100,200 and 400 mg/kg for 45 day and the results showed that serum fasting blood glucose, Glucose – 6 – phosphotase , Fructose 1, 6 –phosphotase in hepatic ...
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1928