Most Popular
EVALUATION OF PHYTOCHEMICALS, REDUCING POWER, ANTIOXIDANT ACTIVITY AND IN-VITRO LIPID PEROXIDATION ACTIVITY OF WHEAT GRASS JUICE
Oxidative stress is a condition due to excessive production of free radicals than the ability of the antioxidant system to counteract them. Antioxidants scavenge and suppress the deleterious effects of free radicals. Both exogenous and endogenous sources of antioxidants are important in pathological conditions. Exogenous antioxidants include dietary sources and even include medicinal plants. These...
4161
1563
SYNTHESIS, ANTI-VIRAL AND CYTOTOXICITY STUDIES OF SOME NOVEL N-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES
A series of novel N-substituted benzimidazole derivatives were synthesized and screened anti-viral activity against a HIV -1 and -2 in MT-4 cells. New compounds were synthesized through modifying the N-1 hydrogen of benzimidazole moiety with the substitution of sulphanilamide, sulphadimidine, sulphamethoxazole, 2-aminopyridine, pthalamide, benzamide, nicotinamide, anthranilic acid and 2- marcapto-...
4160
1977
STUDIES OF DRUG-POLYMER INTERACTIONS OF SIMVASTATIN WITH VARIOUS POLYMERS
The purpose of the present study is to prepare different combinations of drug Simvastatin (SV) with different polymers like Sodium alginate (SA), Hydroxypropylmethylcellulose (HPMC), Pectin (P), Dillenia (D) and Hydroxy propyl β- cyclodextrin. (HPC), thereby determine and report any possible interactions between the drug Simvastatin (SV) and various polymers both from natural and synthetic source...
4160
1713
ANTIBACTERIAL ACTIVITIES OF OLD AND YOUNG LEAVES OF OLEA EUROPAEA (OLIVE TREE) OF ALJOUF REGION, SAUDI ARABIA
Antibacterial activities of different solvent extracts of young and old leaves has been evaluated against Pseudomonas aeureginosa (ATTCC10145) an opportunistic bacteria by Agar Well Diffusion Method. Extracts of olive leaves have been prepared by using standard extraction methods and DMS was used as vehicle for all the extracts. Amikacin was used as standard drug to which P. aeruginosa was found s...
4160
2015
SYNTHESIS AND CHARACTERIZATION OF PVA BASED SERICIN FILM FOR ANTIBACTERIAL WOUND DRESSING
Sericin is a globular protein obtained from degumming of silk cocoon in the silk reeling process. The sericin film was synthesized for the application of antibacterial wound dressing, but it has a low physical property, hence the synthetic polymer was used in the synthesis of highly stable biocompatible film. The PVA based sericin film was prepared by solvent casting method by the addition of synt...
4158
1432
IN-VITRO EVALUATION OF SHEA BUTTER-BASED NYSTATIN MICROPARTICLES
Nystatin, an antifungal drug for mucosal infections has a large dosing frequency and is rapidly inactivated by acids. In order to increase drug stability and reduce dosing frequency and reduce dosing frequency and gastric irritation, formulation into inert lipid matrices as solid lipid microparticles may be utilized. The formulations were done from Shea butter extract using either Tween 20 or Twee...
4157
2302
ETHNO-MEDICINAL STUDY OF HERBS USED BY RURAL AND TRIBAL COMMUNITY IN BETUL DISTRICT OF MADHYA PRADESH, INDIA
The investigation on the local knowledge about traditional herbal medicine is becoming increasingly important in defining strategies and actions for conservation of medicinal plants. This study therefore considered worthwhile to collect information from local rural and tribal population living in Betul district of Madhya Pradesh (India) concerning the use of medicinal plants; identify the most imp...
4157
1429
FORMULATION DEVELOPMENT OF MICROSPONGE BASED DELAYED RELEASE DOSAGE FORM OF LANSOPRAZOLE
The aim of study is to develop microsponge based delayed release dosage form, technique used to manufacture microsponge was quasi emulsion diffusion technique. Eudragit L 100 and Eudragit S 100 polymer is used to incorporate lansoprazole in microsponge. Lansoprazole is acid labile drug hence release of lansoprazole was delayed from acid environment. Microsponge contains porous polymeric microspher...
4157
1747
STUDY ON DETECTION METHODS FOR NOREPINEPHRINE IN BIOLOGICAL SAMPLES
Norepinephrine (NE) is an important catecholamine neurotransmitter that acts as a biochemical messenger in central nervous systems and neuronal cells of mammals, which is secreted and released by the adrenal medulla and the noradrenergic neurons during the synaptic transmission. It is often used for treating bronchial asthma, myocardial infarction hypertension and organic heart disease. Abnormal r...
4156
1509
PROTEIN INTERACTION NETWORK AND DRUG DISCOVERY
Protein conformation and dynamics are influenced by various factors, including binding of ligands, their physico-chemical properties, etc. Every conformational change is dictated by an array of events, as making and breaking of bonds or change in interaction of protein residues. The three dimensional structure of protein molecules are widely investigated, based on small world network approaches, w...
4156
1335