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STUDIES ON THE ANTI-INFLAMMATORY AND ANALGESIC EFFICACY OF SCINDAPSUS OFFICINALIS (ROXB.) SCHOTT IN LABORATORY ANIMALS
This research was focused on the qualitative and quantitative evaluation of anti-inflammatory and analgesic effects of ethanolic extract of Scindapsus officinalis (EESO) fruit in laboratory animals and whether these effects were of any statistical significance. Carrageenan-induced Hind Paw Edema test in long evans rat was the experiment for anti-inflammatory activity of the ethanolic extract of ...
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1660
ANTIMICROBIAL ACTIVITY OF CLEMATIS BRACHIATA THUNB LEAF EXTRACTS
The antimicrobial activity as well as phytochemical screening of the hexane, acetone, methanol and water extracts of Clematis brachiata Thunb (Ranunculaceae) leaves was investigated. The agar dilution assay method was used for the evaluation of the antimicrobial activity of extracts against 10 bacteria and four fungal species. The phytochemical screenings were performed by using the standard proce...
4177
1640
ISOLATION OF TRITERPENES FROM FIORIA VITIFOLIA (L.) AND IT’S ANTIOXIDANT ACTIVITY
Fioria vitifolia L. (Linn.),(Malvacae) has been extensively used in folk medicine for the treatment of common cold, flu, and upper respiratory infections and also used as an immune system booster. The methanolic extract of whole plant of Fioria vitifolia was taken underphytochemical investigation. The methanolic extract was partitioned with different solvent system by increasing their polarities u...
4176
1990
PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND HPTLC FINGER PRINTING OF AN ANTIDIABETIC POLYHERBAL FORMULATION
The aim of the present work was to investigate the phytochemical components of an antidiabetic polyherbal formulation. The formulation was prepared using ingredients of Azadirachta indica A. Juss, Commiphora mukul, Curcuma longa L, Emblica officinalis Gaertn, Garcinia cambogia Gaertn, Gymnema sylvestre Retz, Momordica charantia L, Ocimum sanctum L and Trigonella foenum-graecum L. The formulation w...
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2107
ANTINOCICEPTIVE EFFECTS OF METHANOLIC EXTRACTS OF POTENTILLA ANSERINA IN ANIMAL MODELS
Potentilla anserina (Rosaceae) is a traditional medicinal plant in India, and it is available throughout the Northern hemisphere. This study was intended to evaluate the antinociceptive activity of methanolic extract of Potentilla anserina in acetic acid-induced writhing test in mice and Eddy’s Hot Plate method in Albino rats at the dose level of 75, 150 and 300 mg/kg p.o and the study was compa...
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1538
A STUDY TO ASSESS THE COST EFFECTIVENESS OF HOME BASED EDUCATION PROGRAMME AMONG CLIENTS WITH DIABETES MELLITUS (DM) AT SELECTED VILLAGES IN KANCHEEPURAM DISTRICT, TAMIL NADU, INDIA
Home based education among clients with diabetes mellitus (DM) by diabetes educator has been cost effective although some educational intervention have strong evidence on cost saving. This study aimed to assess the cost effectiveness of home based education programme on diabetic treatment among clients with diabetes mellitus. Community based randomized controlled trial with experimental design w...
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1628
OPTIMIZATION, EVALUATION AND STABILITY STUDY OF NUTRACEUTICAL POWDER FORMULATIONS DEVELOPED FROM EDIBLE SEED AND LEAFY- VEGETABLE SOURCES
Nutraceutical term is a combination of terms nutrient and pharmaceutical. There is a wide scope in applying pharmaceutical formulation parameters to nutraceuticals. Amongst the variety of nutraceuticals available, powder form of nutraceuticals are most popular. The nutraceutical powder mixtures can contain many ingredients, of which the nutrient source contents are generally present in more than 5...
4175
1880
A COMPARATIVE STUDY OF ROSIGLITAZONE AND PIOGLITAZONE TO EVALUATE THE CARDIOVASCULAR EFFECTS IN HIGH FRUCTOSE DIET INDUCED HYPERTENSIVE RATS
Thiazolidinediones (TZDs) were widely used for the treatment of type 2 diabetes. Recent studies have shown that TZDs have paradoxical effects on cardiovascular diseases. The objective of the present study was to investigate the effect of TZDs (Rosiglitazone and Pioglitazone) in High Fructose Diet (HFD) induced hypertension in rats. HFD was given for 14 weeks. After 8 weeks of hypertension inductio...
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1531
STABILITY INDICATING METHOD DEVELOPMENT AND VALIDATION OF REMOGLIFLOZIN ETABONATE IN BULK AND PHARMACEUTICAL DOSAGE FORM BY RP-HPLC
An accurate, precise, and simple stability-indicating and RP-HPLC method was developed and validated for the estimation of Remogliflozin Etabonate in bulk and pharmaceutical dosage forms. Primacel C18 (150 × 4.6mm, 5µm) column, with mobile phase Acetonitrile: Water (70:30, v/v) at isocratic mode, was used for the development of this method. At wavelength 280nm, and flow rate of 1ml/min was maint...
4174
1862
EFFECT OF CURCUMIN SUPPLEMENTATION ON THE SUBMANDIBULAR SALIVARY GLANDS OF D-GALACTOSE INDUCED MALE MICE
Significant increase in the salivary gland lipid peroxidation, fluorescence product as well as accumulation of lipofuscin granules–age pigment was observed after injection of 5% D-galactose 0.5 ml daily for 30 days. Supplementations of turmeric extract (30mg/kg body weight) for 30 days during and after D-galactose treatment significantly reduced all the above parameters. Histochemical changes in...
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