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PHARMACOGNOSTICAL AND PHYTOCHEMICAL EVALUATION OF OUGEINIA OOJEINENSIS (ROXB) HOCHR. BARK
Ougeinia oojeinensis (Roxb) Hochr, an ethanomedicinal plant of Western Ghats seen in deciduous forests. The bark is used to treat various ailments in folk medicine. There are no previous reports on pharmacognostical study on this plant. As a promising ethanomedicinal plant, systematic and detailed pharmacognostical studies were carried out. The present study focused on its macro and micro morpho...
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ANTI TUBERULAR AND ANTHELMINTHIC ACTIVITIES OF AQUEOUS METHANOLIC EXTRACT OF CARALLUAMA ATTENUATA
Caralluma attenuata is a perennial small, leafless succulent plant which grows in tropical and subtropical areas. It belongs to the family Apocyanaceae. The folkal information reveals that the tribes generally chew the whole plant to treat peptic ulcer, diabetes, in weight reduction to suppress hunger and also to produce endurance. It has been reported for the presence of steroids, flavanoids, s...
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HEMATOLOGICAL AND HISTOPATHOLOGICAL STUDIES OF ENDOSPERM-RICH FRACTION OF FLAXSEED IN CHICKS
Flaxseed is being consumed as an ingredient in various food formulations as it plays a major role in the field of diet and disease research due to its potential health benefits associated with a- linolenic acid (57%) and its rich phytoestrogens or lignans. Hence, presently, it is in great demand by food industries and in nutraceutical applications. The present study was carried out using 80, 3...
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FIRST AND SECOND ZAGREB INDICES AND POLYNOMIALS OF V-PHENYLENIC NANOTUBES AND NANOTORI
Let G be a simple molecular graph with vertex and edge sets V(G) and E(G), respectively. In 1972, Gutman and Trinajstić introduced the First and Second Zagreb topological indices of molecular graphs. These topological indices are useful in the study of anti-inflammatory activities of certain chemical instances, and in elsewhere. In this present study, compute the First Zagreb index Zg1(G)= and ...
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EXTRACTION EFFICACY, ANTIBACTERIAL POTENTIAL AND VALIDATION OF RP-HPLC COUPLED WITH DIODE ARRAY DETECTION IN HOLARRHENA PUBESCENS
A rapid, simple, sensitive and reproducible RP-HPLC method was developed for the determination of conessine (bioactive steroidal alkaloid) in Holarrhena pubescens, a highly valued medicinal plant extensively used in pharmaceuticals. Separation was achieved on Discovery (R) RP Amide C16 Supelco column (250 µm x 4.6 µm ID) using a mobile phase of acetonitrile: water (95:5 v/v) with flow rate 0.6...
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SUPPRESSIVE EFFECT OF TEUCRIUM POLIUM ON OXIDATIVE DAMAGES AMONG EXPERIMENTAL STEATOHEPATITIS
Non-alcoholic steatohepatitis (NASH) is a metabolic disorder of the liver that may progress to fibrosis or cirrhosis. In the present study, we examined the possible preventive effect of an extract of Teucrium polium L. (Lamiaceae), a plant with high flavonoid content and antioxidant activity, on experimental NASH. To induce NASH, a methionine and choline deficient (MCD) diet was given to N-Mary ra...
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PREVALENCE OF PATHOGENIC ORGANISMS IN MEAT SAMPLES OF ONGKHARAK NAKHONNAYOK THAILAND
Globally, foodborne pathogens are the origin of diseases and deaths. To prevent the foodborne pathogens billions of dollars spending. Coliforms level, psychrotrophs mesophiles, E. coli, and Staphylococcus aureus, are routinely assessed to determine microbial safety, sanitation conditions, improper hygiene in poultry carcasses. Thai-population consumes more broiler meat due to its availability and ...
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MOLECULAR DOCKING STUDIES OF BMS-378806 ANALOGS AS NOVEL HIV-1 GP120/CD4 INHIBITORS
AIDS, a pandemic disease caused by HIV has a high mortality rate. Therapeutic failures have risen due to the emergence of resistant viral strains and adverse side-effects of Anti-HIV drugs. Thus, there arises a need to develop novel and promising anti-HIV drugs. BMS-378806 (BMS-806) inhibits the initial stages of HIV-1 infection by blocking the binding of viral gp120 protein to host-cell CD4 recep...
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DISPERSIBLE FORMULATION MAKEUPS FOR PEDIATRIC USE: A REVIEW
Childhood is characterized by periods of rapid growth, maturation, and development. There is a change in the magnitude of the dose required during childhood and adolescence. Thus, Paediatric practice requires a range of dosage forms that are acceptable at different ages and abilities and a range of strengths or concentrations allowing administration of the correct age-related dose. Literature show...
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DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR QUANTITATIVE ESTIMATION OF RITONAVIR IN BULK AND PHARMACEUTICAL DOSAGE FORMS
A simple, precise, specific and accurate reverse phase HPLC method has been developed for the determination of Ritonavir in bulk and pharmaceutical dosage forms. The chromatographic separation was achieved on Symmetry C18 (4.6 x 100mm, 3.5 μm) column using a mixture of Buffer: Acetonitrile (50:50) as the mobile phase at a flow rate 1.0 ml/min. Linearity was observed in concentration range of 50-1...
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