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EFFECT OF CURCUMIN SUPPLEMENTATION ON THE SUBMANDIBULAR SALIVARY GLANDS OF D-GALACTOSE INDUCED MALE MICE
Significant increase in the salivary gland lipid peroxidation, fluorescence product as well as accumulation of lipofuscin granules–age pigment was observed after injection of 5% D-galactose 0.5 ml daily for 30 days. Supplementations of turmeric extract (30mg/kg body weight) for 30 days during and after D-galactose treatment significantly reduced all the above parameters. Histochemical changes in...
4164
1698
THE EFFECT OF DOXYCYCLINE HYDROCHLORIDE ON MMP-2 AND 9 IN EXPERIMENTALLY INDUCED PERIODONTITIS – AN ANIMAL STUDY
The periodontal tissues undergo constant changes of remodelling when subject to bacterial infection and the resultant host response. The balance between enzymes secreted by the host such as matrix metalloproteinases (MMPs) and their antagonists tissue inhibitor of metalloproteinases (TIMPs) are major contributors to the progression of periodontal destruction. A sub-type of MMPs referred to gelatin...
4164
1854
ANTINOCICEPTIVE EFFECTS OF METHANOLIC EXTRACTS OF POTENTILLA ANSERINA IN ANIMAL MODELS
Potentilla anserina (Rosaceae) is a traditional medicinal plant in India, and it is available throughout the Northern hemisphere. This study was intended to evaluate the antinociceptive activity of methanolic extract of Potentilla anserina in acetic acid-induced writhing test in mice and Eddy’s Hot Plate method in Albino rats at the dose level of 75, 150 and 300 mg/kg p.o and the study was compa...
4164
1530
HYPER ACCUMULATION OF CADMIUM IN SOLANUM NIGRUM L. AND THEIR EFFECTS ON PHYTO-CHEMICALS AND ANTIOXIDANT ENZYMATIC ACTIVITIES
In the pot experiment, Solanum nigrum L. treated with different concentration of Cd showed high accumulation of Cd in plant. Growth of plant was not significantly affected up to ≤ 50ppm Cd treated plant, The trends of Cd accumulation in plant were leaf>shoot>root with increasing concentration of Cd and DAS. Plant accumulates 298, 92 and 58 ppm of Cd after 60DAS in leaf>shoot>root re...
4163
1810
A STUDY TO ASSESS THE COST EFFECTIVENESS OF HOME BASED EDUCATION PROGRAMME AMONG CLIENTS WITH DIABETES MELLITUS (DM) AT SELECTED VILLAGES IN KANCHEEPURAM DISTRICT, TAMIL NADU, INDIA
Home based education among clients with diabetes mellitus (DM) by diabetes educator has been cost effective although some educational intervention have strong evidence on cost saving. This study aimed to assess the cost effectiveness of home based education programme on diabetic treatment among clients with diabetes mellitus. Community based randomized controlled trial with experimental design w...
4163
1619
TO EVALUATE PHYSICOCHEMICAL CHARACTERISTICS OF GRANULATION FOR LACTOSE AND ACETAMINOPHEN BY UTILIZING RHEOLOGICAL AND THERMAL TOOLS
The purpose of the study is to evaluate the effect of the granulation properties of Lactose depending upon the use of its crystalline forms and the impact of active (Acetaminophen) concentration using rheological and thermal tools. Lactose was chosen as an excipient available in different hydrate forms (anhydrous and monohydrate) and Acetaminophen (APAP) was selected as a model drug for the subjec...
4163
1708
OPTIMIZATION, EVALUATION AND STABILITY STUDY OF NUTRACEUTICAL POWDER FORMULATIONS DEVELOPED FROM EDIBLE SEED AND LEAFY- VEGETABLE SOURCES
Nutraceutical term is a combination of terms nutrient and pharmaceutical. There is a wide scope in applying pharmaceutical formulation parameters to nutraceuticals. Amongst the variety of nutraceuticals available, powder form of nutraceuticals are most popular. The nutraceutical powder mixtures can contain many ingredients, of which the nutrient source contents are generally present in more than 5...
4163
1873
EVALUATION OF ANTIDEPRESANT ACTIVITY OF SPINACIA OLERACEAE BY USING ALBINO RATS
Herbal and natural products of folk medicine have been used for centuries in every culture throughout the world. Scientists and medical professionals have shown increased interest in this field as they recognize the true health benefits of these remedies. Spinach is a leafy green vegetable that came originally from south-western Asia and is now grown in most parts of the world. Scientifically it i...
4162
1570
SYNTHESIS OF NEW SERIES OF THIENYL ACRYLATE DERIVATIVES VIA BAYLIS-HILLMAN REACTION AND EVALUATION OF ANTIMICROBIAL ACTIVITY
A series of new Thienyl acrylate compounds were synthesized via Baylis-Hillman reaction and tested to demonstrate in vitro antimicrobial activity. Some of these compounds exhibited a very good activity against Gram positive strains. The structure of these newly synthesized compounds were conformed by 1H NMR, IR, Mass and Elemental analysis, some of them were also confirmed by 13C NMR....
4162
1503
MICROWAVE-ASSISTED RAPID GREEN SYNTHESIS OF SILVER NANOPARTICLES USING SARACA INDICA LEAF EXTRACT AND THEIR ANTIBACTERIAL POTENTIAL
The present study reports an environmentally friendly, microwave-assisted rapid green synthetic method using Saraca indica leaf extract makes a fast and convenient method for the synthesis of silver nanoparticles and can reduce most of the silver ions into silver nanoparticles within 180 sec of reaction time with the aid of microwave. The synthesized nanoparticles were characterized using UV-visib...
4161
1855