Pages Menu
TwitterRssFacebookWhatsapplinkedin
ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

Categories Menu

Most Popular

 
Title
Views
PDF
Cited
12.

OPTIMIZATION, EVALUATION AND STABILITY STUDY OF NUTRACEUTICAL POWDER FORMULATIONS DEVELOPED FROM EDIBLE SEED AND LEAFY- VEGETABLE SOURCES

Nutraceutical term is a combination of terms nutrient and pharmaceutical. There is a wide scope in applying pharmaceutical formulation parameters to nutraceuticals. Amongst the variety of nutraceuticals available, powder form of nutraceuticals are most popular. The nutraceutical powder mixtures can contain many ingredients, of which the nutrient source contents are generally present in more than 5...

M. C. Singh *, K. N. Gujar and I. Singhvi

S.T.E.S’s Smt. Kashibai Navale College of Pharmacy, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.11(4).1617-28

1617-1628

4170

1879

23.

THREE-DIMENSIONAL QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP STUDIES ON DIVERSE STRUCTURAL CLASSES OF NATURAL FLAVONOIDS AS AMV AND HIV REVERSE TRANSCRIPTASE INHIBITORS USING CoMFA AND CoMSIA

In this study, comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were performed on a series of 73 experimentally reported natural flavonoid derivatives as AMV and HIV Reverse transcriptase (RT) inhibitors with pIC50 values ranging from 4.00 to 5.92. Based on alignment, highly predictive CoMFA and CoMSIA were obtained with cross-validated q...

Shravan Kumar Gunda*, Sri Swathi Mutya, Sharada Durgam, Vijaya Lakshmi Lokirevu and Mahmood Shaik

Bioinformatics Division, Osmania University, Hyderabad, India

DOI: 10.13040/IJPSR.0975-8232.6(4).1509-36

1517-1527

4169

1562

27.

SPECTROFLUORIMETRIC STUDIES ON THE INTERACTION OF MOXIFLOXACIN WITH HERRING SPERM DNA

Moxifloxacin (MOX) is a fourth-generation synthetic fluoroquinolone antibacterial agent with many important therapeutic properties.  Fluorescence measurement was used to study the interaction of MOX with herring sperm DNA (Hs-DNA) in Tris-HCl, buffer of pH 7.4.  The intercalative binding mode and a static quenching mechanism were confirmed by the Stern-Volmer quenching rate constant (Kq) of 5.61...

Babu G. Gowda*, M. Mallappa, A. Shivakumar and R. Nageshbabu

Assistant Professor, Department of Chemistry, Maharani’s Science College for Women, Palace Road, Bangalore-560 001 India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(12).5276-82

5276-5282

4168

1988

22.

SYNTHESIS OF NEW SERIES OF THIENYL ACRYLATE DERIVATIVES VIA BAYLIS-HILLMAN REACTION AND EVALUATION OF ANTIMICROBIAL ACTIVITY

A series of new Thienyl acrylate compounds were synthesized via Baylis-Hillman reaction and tested to demonstrate in vitro antimicrobial activity. Some of these compounds exhibited a very good activity against Gram positive strains. The structure of these newly synthesized compounds were conformed by 1H NMR, IR, Mass and Elemental analysis, some of them were also confirmed by 13C NMR....

Anand Sivadas *, Maneesh Paul Satyaseela , Thirunavukkarasu Bharani , Sampath Kumar Upparapalli and Narayanan Subbaraya

Research Scientist-II, Department of Synthetic chemistry, Orchid Chemicals and pharmaceutical Ltd, Research and development, Shollinganallur, Chennai , Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(4).893-04

893-904

4168

1505

19.

CYTOGENETIC STUDY OF CHROMOSOMAL ABERRATIONS ASSOCIATED WITH ACUTE LEUKEMIA

The most common cause of death is bone marrow failure. Chromosomal analysis is essential for the diagnosis, response to treatment and prognosis of leukemia. Conventional karyotyping which shows the structural, numerical and compound aberrations have improved the genetic diagnosis of leukemia. The bone marrow samples from patients (2-60yrs) of 53 patients (32 male and 21 female) suffering from vari...

D. N. Mishra , S. K. Panda , S. K. Sahoo, J. S. Prusti , T. Patra, P. Panda , P. K. Chinara and S. Rout *

Department of Anatomy , AIIMS, Bhubaneswar, India.

DOI: 10.13040/IJPSR.0975-8232.6(4).1479-88

1479-1488

4168

1435

36.

THE EFFECT OF DOXYCYCLINE HYDROCHLORIDE ON MMP-2 AND 9 IN EXPERIMENTALLY INDUCED PERIODONTITIS – AN ANIMAL STUDY

The periodontal tissues undergo constant changes of remodelling when subject to bacterial infection and the resultant host response. The balance between enzymes secreted by the host such as matrix metalloproteinases (MMPs) and their antagonists tissue inhibitor of metalloproteinases (TIMPs) are major contributors to the progression of periodontal destruction. A sub-type of MMPs referred to gelatin...

H. Parthsarathy, S. Aishwarya and C. A. Jacob *

Department of Periodontology, SRM Dental College, Bharathi Salai, Ramapuram, Chennai - 600089, TN, India

DOI: 10.13040/IJPSR.0975-8232.7(2).765-72

765-72

4168

1858

39.

HYPER ACCUMULATION OF CADMIUM IN SOLANUM NIGRUM L. AND THEIR EFFECTS ON PHYTO-CHEMICALS AND ANTIOXIDANT ENZYMATIC ACTIVITIES

In the pot experiment, Solanum nigrum L. treated with different concentration of Cd showed high accumulation of Cd in plant. Growth of plant was not significantly affected up to ≤ 50ppm Cd treated plant, The trends of Cd accumulation in plant were leaf>shoot>root with increasing concentration of Cd and DAS. Plant accumulates 298, 92 and 58 ppm of Cd after 60DAS in leaf>shoot>root re...

G.K. Dwivedi*, S.K. Upadhyay , A.K. Mishra and Arvind Kumar Singh

Department of Botany, T.D.P.G. College, Jaunpur-222001, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(4).1424-30

1424-1430

4167

1812

31.

EVALUATION OF ANTIDEPRESANT ACTIVITY OF SPINACIA OLERACEAE BY USING ALBINO RATS

Herbal and natural products of folk medicine have been used for centuries in every culture throughout the world. Scientists and medical professionals have shown increased interest in this field as they recognize the true health benefits of these remedies. Spinach is a leafy green vegetable that came originally from south-western Asia and is now grown in most parts of the world. Scientifically it i...

Rajya Laxmi Gudepu*, S.V. Mahalakshmi Rampalli and J. Yasodha Krishna

Department of Pharmacology, Sri Sarada College of Pharmacy, Bhongir, Nalgonda- 508116, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(12).4692-96

4692-4696

4167

1571

15.

SYNTHESIS, ANTI-VIRAL AND CYTOTOXICITY STUDIES OF SOME NOVEL N-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES

A series of novel N-substituted benzimidazole derivatives were synthesized and screened anti-viral activity against a HIV -1 and -2 in MT-4 cells. New compounds were synthesized through modifying the N-1 hydrogen of benzimidazole moiety with the substitution of sulphanilamide, sulphadimidine, sulphamethoxazole, 2-aminopyridine, pthalamide, benzamide, nicotinamide, anthranilic acid and 2- marcapto-...

Periyasamy Selvam*, Dhani Ram Lakra and Christophe Pannecouque

Arulmigu Kalasalingam College of Pharmacy, Krishnankoil, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(9).105-09

105-109

4167

1980

32.

EVALUATION OF PHYTOCHEMICALS, REDUCING POWER, ANTIOXIDANT ACTIVITY AND IN-VITRO LIPID PEROXIDATION ACTIVITY OF WHEAT GRASS JUICE

Oxidative stress is a condition due to excessive production of free radicals than the ability of the antioxidant system to counteract them. Antioxidants scavenge and suppress the deleterious effects of free radicals. Both exogenous and endogenous sources of antioxidants are important in pathological conditions. Exogenous antioxidants include dietary sources and even include medicinal plants. These...

S. N. Jangle and P. Padmanabhan *

Department of Biochemistry, Rural Medical College, Pravara Institute of Medical Sciences (DU), Loni , Ahmednagar, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.7(8).3436-40

3436-40

4165

1568