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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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54.

EVALUATING HYPOLIPIDEMIC POTENTIAL OF KASNI SEED (CICHORIUM INTYBUS) PREPARATIONS IN NEWLY DIAGNOSED PATIENTS OF METABOLIC DISORDER

Objective: To evaluate hypolipidemic potential of Kasni (Cichorium intybus) seed preparations combined with oral hypoglycemic agent in treatment of patients of newly diagnosed type 2 DM. Methods: Newly diagnosed 90 patients of Type2DM, age 35-65years, of either sex were divided into 3 groups. Each group having 30 patients (19 male and 11 females) matched with each other in terms of age and sex. In...

Praveen Katiyar * , Amod Kumar , Arvind K. Mishra , Rakesh K. Dixit and Ajay K. Gupta

Department of Pharmacology & Therapeutics , King George's Medical University, Lucknow, U.P., India

DOI: 10.13040/IJPSR.0975-8232.6(9).4092-02

4092-02

3058

1166

34.

SYNTHESIS, CHARACTERIZATION AND IN VITRO ANTICANCER EVALUATION OF BIS-[1,5]-BENZOTHIAZEPINES AGAINST HUMAN BREAST CANCER CELL LINE MCF-7

Bis-[1,5]-benzothiazepines (3a-i) containing two 1,5-benzothiazepine nuclei in a single molecule were synthesized by cyclocondensation reaction of bis-chalcones (1a-i) with two equivalent of 2-aminobenzenethiol (2). All the synthesized compounds were characterized by IR, 1H NMR,13C NMR and mass spectral analysis. Anticancer activity of the synthesized compounds against human breast cancer cell lin...

R. N. Deshmukh and R. V. Dengle *

Department of Chemistry, Vivekanand College, Kolhapur, Maharashtra, India

DOI: 10.13040/IJPSR.0975-8232.7(12).5024-29

5024-5029

3058

1089

45.

PREVALENCE AND CORRELATION OF VIRAL INFECTION (HEPATITIS B OR/AND HEPATITIS C) AMONG HYPERTENSIVE AND DIABETIC PATIENTS IN MALAYSIA AND INDONESIA WHO UNDERWENT HEMODIALYSIS

Background: Increase prevalence of viral infection such as hepatitis B or/and hepatitis C are followed by high incidence of mortality among hemodialysis patients. Objective: To determine prevalence and correlation of viral infection (Hepatitis B or/and Hepatitis C) among Hemodialysis Patients that died for the last five years in Indonesia and Malaysia in relation to gender, age, causes, and countr...

D. L. Ramatillah *, S. A. Syed Sulaiman, A. Hayat Khan, D. DR Ong Loke Meng and Markum

Discipline of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia.

DOI: 10.13040/IJPSR.0975-8232.8(6).2677-81

2677-2681

3058

1140

65.

STUDY OF STORAGE PERIODS OF CULTURE SUSPENSION OF STAPHYLOCOCCUS AUREUS

Staphylococcus aureus ATCC 6538 is an important strain of pharmaceutical and biotechnological industries. We studied the viability of culture suspension of Staphylococcus aureus strain ATCC 6538 at 2 to 8°C up to 360 days in 0.9% w/v NaCl. The culture suspension containing 10000 cfu/ml used in the study was stored at 2 to 8°C for 360 days in 0.9% w/v NaCl. Using 10 µl of above culture suspensio...

Kundan Kumar*, I.N. Mishra and Sandhya Jha

University Department of Bio-Technology, L.N. Mithila University, Darbhanga-846004, Bihar, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(1).483-85

483-485

3057

1078

35.

PHYTOCHEMICAL SCREENING AND IN-VITRO ANTIMICROBIAL ACTIVITY OF POGOSTEMON QUADRIFOLIUS (BENTH) OF LAMIACEAE

Pogostemon quadrifolius (Benth.) is a medicinal aromatic shrub in family Lamiaceae which is used as folk medicine in India. This present study deals with the preliminary screening of Pogostemon quadrifolius antimicrobial activity and TLC profiling of the crude plant extract. Cold extraction technique was carried out to prepare the crude plant extract, which was further screened for the presence of...

M. M. Rahman, R. Devi and P. U. Megha *

Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.9(6).2438-45

2438-2445

3057

1141

43.

SUCCESS AND FAILURE WITH INTRALESIONAL 3% SODIUM TETRADECYL SULFATE SCLEROSING AGENT IN TWO CASES OF INTRAORAL HEMANGIOMA

Vascular malformations are one of the most common lesions of the oral cavity. The lesion may be a congenital malformation observed in neonates or arteriovenous malformation observed in adults. The treatment of these lesions includes surgical excision, cryotherapy, selective embolization and treatment with intralesional sclerosing agents. We present two cases of benign oral vascular lesions treated...

E. B. Kayalvizhi *, N. Megalaa, K. Thirumurugan, R. Kanmani and G. Sitra

Department of Oral Medicine and Radiology, Madha Dental College and Hospital, Kundrathur Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3069-74

3069-3074

3056

981

47.

BIOCHEMICAL ANALYSIS IN PATIENTS WITH MAJOR DEPRESSIVE DISORDER IN JAMMU POPULATION

The study was conducted to study biochemical parameters in 42 major depressive disorder (MDD) patients, 22 males and 20 females (age range 18 - 55 years) visiting the Psychiatric Department, Government Medical College, Jammu. The smoking and alcohol intake was much lower (95.24% and 88.09%) in patients (both male and female) diagnosed with MDD. The well being status is also 76.19% satisfactory wit...

A. Kumar, R. Sharma*, M. Arora and R. C. Gupta

Department of Zoology, MCM DAV College, Chandigarh, Punjab, India.

DOI: 10.13040/IJPSR.0975-8232.9(1).354-60

354-360

3056

949

8.

PHARMACOLOGICAL STUDY OF THE PELTOPHORUM PTEROCARPUM FLOWER

The present study was designed to investigate in vivo analgesic and cytotoxicity as well as in vitro antibacterial activities of the methanol: ethylacetate (1: 9) extract of the flowers of Peltophorum pterocarpum. Analgesic activity was assayed by acetic acid induced assay method wherein the extract showed moderate activity in a dose dependent manner. In respect of in vivo cytotoxicity, the flower...

M. Saiful Islam , Ronok Zahan , M. Badrul Alam , Marufa Naznin , M. A. Mosaddik , M. Ekramul Haque*

PhD, Department of Pharmacy, University of Rajshahi, Rajshahi - 6205, Bangladesh

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(9).2309-13

2309-2313

3055

979

6.

ANTIMICROBIAL SCREENING AND BRINE SHRIMP LETHALITY BIOASSAY OF TINOSPORA CORDIFOLIA (FAM: MENISPERMACEAE)

Tinospora cordifolia (Fam: Menispermaceae) has been investigated for evaluation of the biological activities. The stem of Tinospora cordifolia were extracted with carbon tetrachloride, n-hexane and methanol were collected and afford 4.0 mg, 4.0 mg, and 4.0 mg, respectively for the test. The crude carbon tetrachloride, n-hexane, and methanol extract of the plant were subjected to antimicrobial scre...

Mohammad Kaisarul Islam* and Khondaker Ashakin

Department of Pharmaceutical & Biological Chemistry, School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(12).3091-95

3091-3095

3055

1089

13.

MOTION SICKNESS INDUCES PHYSIOLOGICAL AND NEURONAL ALTERATIONS IN MOUSE MODEL

Motion sickness (MS) is a conflict between visual and vestibular system leading to nausea and vomiting. The present study aimed to standardize a method to induce MS in Balb/c mice model. Conditioned taste aversion (CTA) utilizing saccharin solution (SS) was used as MS index. Mice were divided into three groups (n=6); group 1 (G1), group 2 (G2) and group 3 (G3). Two bottle test [TBT, both bottles c...

D. U. Maheswari, T. Anand *, T. M. Manu, F. Khanum and R. K. Sharma

Nutrition, Biochemistry and Toxicology Division, Defence Food Research Laboratory, Siddarthanagar, Mysore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(4).1650-59

1650-1659

3055

1198