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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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39.

DETERMINATION OF QUERCETIN BY HPTLC METHOD PRESENT IN ZYMODYNE SYRUP- A POLY HERBAL FORMULATION

Zymodyne Syrup is poly herbal formulation made by Ayrulab Herbals Pvt. Ltd., as an appetite enhancer. This formulation contains various 17 plant extract from these 6 plants namely Cyperus rotundus, Bacopa monnieri, Glycyrrhiza glabra, Phyllanthus amarus, Asparagus racemosus, and Tribulus terrestris  contains Quercetin flavonoid as a chemical constitute and it can be determined by HPTLC method. Th...

Saurabh Parmar*, Nihar Shah , Megha Kasarwala , Madhavika Virpura , Kinjal Shah , and Piyush Patel

Hariom Pharmacy College, Ambav-388250, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(10).2724-28

2724-2728

4228

1912

27.

EVALUATION OF ANTIOXIDANT AND ANTI-ULCER ACTIVITY OF SMILAX PERFOLIATA LINN.

The leaves and fruits of Smilax perfoliata are traditionally used for treatment of various ailments such as rheumatism, lumbago, nourishing the functions of spleen, stomach, muscle and bone. The intent of the present study was to evaluate the antioxidant and anti-ulcer activity of ethanolic leaves and fruits extract of Smilax perfoliata Linn in albino rats. Gastric ulcers were induced by employing...

S. Abdul Arsalan *, S. B. Mahmood, S. Rashid Ali, A. Begum, Md. Ismail, Md. Akbar Siddiq

Sultan ul Uloom college of Pharmacy, Mount Pleasant, Hyderabad, Adhra Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.6(6).2491-95

2491-95

4228

1662

48.

PREPARATION, STANDARDIZATION AND EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF ARKA LAVANA

The liver is a vital organ of the human body. It is responsible for protecting the body from harmful substances and the maintenance of good health. In last few years, various types of liver disorders, such as drug-induced liver disease, hepatomegaly, fatty liver disease, liver cirrhosis, autoimmune hepatitis, chronic viral hepatitis, autoimmune hepatitis, etc. are become a people’s health proble...

J. Singh, A. K. Singh, A. K. Kushwaha, D. N. S. Gautam and M. K. Nandi *

Department of Medicinal Chemistry, Faculty of Ayurveda, IMS, BHU, Varanasi, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(12).5612-21

5612-5621

4228

1813

40.

RENOPROTECTIVE EFFECT OF OCIMUM SANCTUM IN COMPARISON WITH OLMESARTAN MEDOXOMIL AND PITAVASTATIN IN METFORMIN TREATED DIABETIC RATS

Nephropathy is an important comorbidity associated with diabetes leading to chronic kidney disease. We studied the effect of Ocimum sanctum in comparison to Olmesartanmedoxomil, Pitavastatin and their combination in prevention of this comorbidity. Male Wistar rats were given streptozotocin to induce diabetes and randomly divided into groups. Group 1 (Control group) received Metformin (94.5mg/kg/da...

S. Thadani *, M. T. Salman, S. Tewari, S. Singh, D. Bhagchandani and A. Ahmad

Era’s Lucknow Medical College, Sarfarazganj, Hardoi Road, Lucknow, Uttar Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.6(10).4433-41

4433-41

4227

1791

18.

A CASE CONTROL STUDY OF OXIDATIVE STRESS IN TUNISIAN PATIENTS WITH ISCHEMIC HEART DISEASE

Ischemic heart disease (IHD) is the major cause of morbid-mortality in most countries. The involvement of oxidative stress (OS) in the development of atherosclerosis, ischemic cardiopathy triggering phenomen, has been investigated. Serum total homocysteine (Hcy) concentration was measured by fluorescence polarization immunoessay. Plasma levels of substances reacting with thiobarbituric acid (TBARS...

S. Khelil *, M. Ben-Hadj-Mohamed , L. Khlifi, M. Ben Dbibis, H. Chahed, S. Ferchichi, S. Ernez and A. Miled

Biochemistry Laboratory, Farhat Hached hospital, Sousse, Tunisia

DOI: 10.13040/IJPSR.0975-8232.7(11).4449-55

4449-55

4227

1683

22.

BIOMIMETIC SYNTHESIS OF CdSe NANOPARTICLES WITH POTENTIAL BIOIMAGING APPLICATIONS

This study presents in vitro biomimetic synthesis of CdSe nanoparticles using the enzyme, NADPH dependent-Nitrate reductase purified from fungus, Fusarium oxysporum. The synthesis of CdSe nanoparticles was accomplished in the presence of a synthetic peptide having amino acid sequence (γ-Glu-Cys-Glu-Cys)-Gly, which acted as binding molecule. The nanoparticles were synthesized in the size range of ...

Abu A. Ansary *, Imran Uddin and Muhammed I. Khan

Division of Biochemical Sciences, National Chemical Laboratory, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.8(6).2526-32

2526-2532

4227

1572

44.

RISK ASSESSMENT OF SOME HERBAL POWDERS AND HERBAL FORMULATIONS CONTAMINATED WITH HEAVY METALS

Ten herbal medicines, Four herb choornam (Trikatu, Hingwashtak, Triphala and sitopladi) and five herbal compounds - Kutajghan Vati, Gandhak Rasayan, Sarivadi Vati, Chanderprabha Vati, Shankh Vati were tested for levels of heavy metals (Lead, copper, cadmium, iron, chromium, manganese, nickel and zinc). Both herbal extracts and herbal formulations showed the presence of heavy metals. Concentrations...

M. Deswal, P. Deswal and J. S. Laura *

Department of Environmental Sciences, Maharshi Dayanand University, Rohtak, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.10(1).393-00

393-400

4227

1832

31.

EVALUATION OF BONE MARROW FOR HEMATOLOGICAL ANOMALIES IN INDIAN PEDIATRIC AND ADULT PATIENTS: A SINGLE TERTIARY CARE CENTER STUDY

Bone marrow aspiration can determine the metastatic deposits, degree of cellularity and fibrosis readily. A retrospective analysis of bone marrow aspiration and biopsy, in children and adult patients with hematological anomalies, were performed in 674 cases for different indication of hematological abnormalities from January 2013 to March 2014. Cases were analyzed in detail regarding clinical, hem...

Ishwar Singh , Rohit Jain , G. N. Gupta and P. K. Goyal *

Radiation & Cancer Biology Laboratory, Department of Zoology, University of Rajasthan, Jaipur, Rajasthan - 302 004, India

DOI: 10.13040/IJPSR.0975-8232.6(4).1584-89

1584-1589

4226

1579

11.

BROMELAIN PLUS PEROXIDASE FROM PINEAPPLE INDUCES APOPTOSIS VIA MITOCHONDRIAL DEPENDENT PATHWAY IN LYMPHOMA CELLS

Bromelain is a protease present in pineapple fruit and stem. It is reported that commercially available pure bromelain has anticancer, anti-inflammatory and other therapeutic effects. But there are few reports available on the biological activity of bromelain along with peroxidase which is present in pineapple fruit extract. The aim of the present study was to investigate the effect of bromelain w...

R. Debnath, D. Majumder, A. K. Singha, D. Ghosh and D. Maiti *

Immunology Microbiology Lab, Department of Human Physiology, Tripura University, Suryamaninagar, Tripura, India.

DOI: 10.13040/IJPSR.0975-8232.9(11).4610-18

4610-4618

4226

1603

29.

PHYTOCHEMICAL PROFILING AND ANTICANCER ACTIVITY OF DRAGON FRUIT HYLOCEREUS UNDATUS EXTRACTS AGAINST HUMAN HEPATOCELLULAR CARCINOMA CANCER (HEPG-2) CELLS

To investigate the phytoconstituents and anticancer potential followed by apoptotic studies of H. undatus fruit extracts on HepG-2 cells. Qualitative phytochemical profiling and anti-proliferation activity of Aqueous, Chloroform, Ethyl acetate, Hexane, and Methanol extracts of dragon fruit pulp was carried out. Based on the results of anti-proliferation studies, methanol extract was taken further ...

K. Padmavathy, K. Sivakumari *, S. Karthika, S. Rajesh and K. Ashok

Department of Zoology, Presidency College, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.12(5).2770-78

2770-2778

4226

1554