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ANTIMICROBIAL ACTIVITY OF PRICKLY CHAFF (ACHYRANTHES ASPERA) SEED TRYPSIN INHIBITOR
Trypsin inhibitor (AATI) was purified from the seeds of Achyranthes aspera to homogeneity by conventional methods and its antimicrobial activity was tested on selected pathogenic microbes. The inhibitor significantly affected the growth of Proteus vulgaris followed by Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Klebsiella pneumonia with zones of inhibition recorded as 28mm, 26mm...
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1707
CHARACTERIZATION OF ANTIOXIDANT AND CYTOTOXIC POTENTIAL OF METHANOLIC EXTRACTS OF DIFFERENT PARTS OF AEGLE MARMELOS (L.)
Aegle marmelos(L.), family rutaceae is highly reputed medicinal tree commonly known as the bael. All parts of the plant have medicinal properties and extensively used by the traditional medicine practitioners of Bangladesh in different health ailments like Diabetes, Diarrhea, Jaundice, typhoid. The present study was dedicated to investigate phytochemical and pharmacological properties of ripe frui...
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1632
ANTIBIOTIC RESISTANCE ISSUES IN CLINICAL PATHOGENS: A REVIEW
Antibiotic resistance in pathogens is on the increase but in the past few decades this problem raised a deepening concern among scientific community in terms of the clinical management of infectious diseases. In this review, the common gram negative clinically significant pathogenic bacteria who have acquired resistance with passage of time like Shigella dysenteriae, Sh. Boydii, Sh. Flexneri, List...
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1494
STUDIES ON PHENOTYPIC CHARACTERIZATION AND SELECTIVE VIRULENCE FACTORS OF CANDIDA SPP. AND CRYPTOCOCCUS NEOFORMANS AND IN VITRO SUSCEPTIBILITY OF THESE ORGANISMS TO THE CONVENTIONAL AMPHOTERICIN B AND FUNGISOMETM
The human fungal infections have increased tremendously in our country, especially candidal infections. Cryptococcus neoformans is encapsulated yeast, causes life-threatening infections in immuno-compromised individuals such as AIDS. Meningoencephalitis is the serious consequence of C. neoformans infection. Studies are therefore, required for identification of these fungal...
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2262
PHYTOTHERAPY AS NEW APPROACH TO TREAT SCORPION ENVENOMATION: EXPERIMENTAL STUDY
Citrullus colocynthis is a wild common plant in arid and semi arid areas of Algeria which are characterized by high incidence of scorpion envenomation. It is used in Algeria to treat many diseases. In order to optimize and develop new therapeutic strategies for scorpion envenoming, a phytotherapeutic approach has been investigated. Pharmacological properties of Citrullus colocynthis were evaluated...
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CYTOLOGICAL STUDIES OF TWO SPECIES OF GENUS DELONIX
Many cytological characteristics were studied in two species of Genus Delonix i.e., D. regia and D. elata . Delonix regia possessed 2n = 28 chromosome number. Both univalent as well as bivalents occurred invariably in this plant species, the former type being predominant over latter type. The chiasma frequency per PMc varied from 8-12 with average being 15.82. The chiasma frequency per chromosom...
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1554
DEVELOPMENT, EVALUATION AND TARGETING OF IMATINIB MESYLATE LOADED SOLID LIPID NANOPARTICLES TO THE LYMPHATIC SYSTEM
For a formulation scientist, the delivery of therapeutic agents to the diseased organ has been a challenging problem. It is expected to improve the therapeutic index and reduce side effects of a drug by good delivery strategy to diseased organ. The objective of this investigation is to evaluate the targeting potential of solid lipid nanoparticle (SLN) formulation of imatinib mesylate to the lympha...
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1917
PHARMACOKINETIC STUDY OF ANDROGRAPHIS PANICULATA ETHANOLIC EXTRACT TABLET
Andrographis paniculata (Burm. F) Nees, commonly known as the “king of bitters,” is an herbaceous plant belonging to the Acanthaceae and is found throughout tropical and subtropical Asia, Southeast Asia, and India. Andrographolide, a bitter diterpenoid, is the major active principle present in the plant. Authors have already worked on the phytochemical investigation, analgesic and antipyretic ...
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2025
FORMULATION AND IN-VITRO EVALUATION OF ZIDOVUDINE LOADED ETHYL CELLULOSE MICROCAPSULES
Microencapsulation is a well-known method that is used to modify and retard drug release. In this study, the preparation of Zidovudine loaded microcapsule was accomplished in order to assess the suitability of them for production of oral/vaginal sustained release multiparticulate dosage form of Zidovudine.Microcapsules were prepared using the solvent evaporation method. The effect of formulation v...
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IN VITRO ANTIOXIDANT ACTIVITY OF FRUITS OF HUGONIA MYSTAX L. (LINACEAE)
The plant Hugonia mystax L., is a woody evergreen liana belonging to the family Linaceae, locally knows as Modirakanni. Ethnobotanically the tender fruits were used for rheumatism and biological activities like antimicrobial were reported. Present study find outs the scientifically evidence of fruits of Hugonia mystax for its antioxidant property. The different extract of fruits was obtained by su...
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