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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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52.

IN VIVO AND IN VITRO DETERMINATION OF TOTAL PHENOLS, ASCORBIC ACID CONTENT AND ANTIOXIDANT ACTIVITY IN PLUCHEA LANCEOLATA OLIVER & HIERN.

The present investigation deals with the determination of in vitro antioxidant activity as well as the phenols and ascorbic acid content in in vivo (leaf, stem, root) and in vitro (unorganised static callus cultures) plant parts of Pluchea lanceolata. Unorganised static callus cultures (eighteen months old) were grown on MS medium supplemented with NAA (1.0 mg/l) and BAP (0.5 mg/l) using leaf expl...

Deepika Arya *, Vidya Patni Preeta Nair and Radha D. Kale

Post Doctoral Fellow Department of Biotechnology, Mount Carmel College, Bangalore-560052, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).875-79

875-879

4207

1915

50.

SCREENING OF INDIGENOUS MEDICINAL PLANTS FOR THEIR ACARICIDAL ACTIVITY AGAINST CATTLE TICKS UNDER IN VIVO CONDITION

The acaricidal activity of leaf extracts of Annona squamosa, Azadirachta indica and Calotropis procera were tested against the cattle ticks under in vivo condition.  Plants were extracted with methanol and water and the extracts were tested against the cattle ticks under in vivo condition. The aqueous and alcoholic extracts of A. indica showed maximum mortality rate of ticks followed by A. squamo...

V. Nithya , M. Kamalam* and T. Umakanthan

Department of Botany, PSGR Krishnammal college for Women and Veterinary Hospital , Kanjampatty (PO), Pollachi, Coimbatore(Dt), Tamil Nadu, India

DOI: 10.13040/IJPSR.0975-8232.6(7).3049-52

3049-52

4207

1890

52.

IN VITRO AND IN VIVO CHARACTERIZATION OF GLIMEPIRIDE MICROPARTICLES

In the present investigation, controlled release microparticles of Glimepiride were prepared by emulsion solvent evaporation technique using cellulose acetate as release retardant polymer. The microparticles were evaluated for In-Vitro release study and In-Vivo evaluation. The microparticles were subjected to In-vitro release studies by employing 7.8 pH phosphate buffer as dissolution medium. The ...

Balagani Pavan Kumar *, Irisappan Sarath Chandiran and Korlakunta Narasimha Jayaveera

Department of Pharmaceutics, Gokula Krishna College of Pharmacy, Sullurpet, A.P, India

DOI: 10.13040/IJPSR.0975-8232.6(8).3558-62

3558-62

4207

1880

51.

BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF CANDESARTAN BY DERIVATIVE SPECTROSCOPY (FIRST ORDER)

Candesartan cilexetil, a prodrug is a racemic mixture containing one chiral center at the cyclohexyloxy-carbonyloxy- ethyl ester group. It is soluble in dimethyl formamide, acetone, methanol, 0.1 N sodium hydroxide solution and insoluble in water. Objective of the present study was to develop a simple, sensitive, accurate, precise and rapid derivative spectrophotometric bioanalytical method for th...

Gunjan Kalyani * and Vishal S Deshmukh

National Center for Natural Resources (NCNR) Project, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, India

DOI: 10.13040/IJPSR.0975-8232.7(7).3148-53

3148-53

4207

1622

8.

RECOVERY OF LIVER DAMAGED BY CCl4 UNDER TREATMENT BY CONJUGATE OF DRUG XYMEDON WITH L-ASCORBIC ACID

The aim of the study is to investigate the capacity of pyrimidine derivatives like the active ingredient of Xymedon (I) and its derivative, salt-like conjugate with L-ascorbic acid (II) to stimulate liver recovery when damaged by toxic hepatitis. The study was done on out breed white rats. The liver damage was induced by carbon tetrachloride (injected 50% oil solution subcutaneously, once per day,...

A. B. Vyshtakalyuk *, N. G. Nazarov, V. E. Semenov, I. V. Galyametdinova, R. G. K. Diabankana, A. G. Porfiriev and V. V. Zobov

A.E. Arbuzov Institute of Organic and Physical Chemistry, Subdivision of the Federal State Budgetary Institution of Science, Kazan Scientific Center of Russian Academy of Sciences, Kazan, Russia.

DOI: 10.13040/IJPSR.0975-8232.9(10).4117-26

4117-4126

4207

1668

35.

ANTIOXIDANT ACTIVITY OF TAXIFOLIN OBTAINED FROM METHANOLIC EXTRACTS OF CORDIA DICHOTOMA LINN. SEEDS

Cordia dichotoma L. family Boraginaceae is a medium sized tree, is taken as food. The immature fruits are pickled and are also used as vegetable. The various extracts and fractions of Cordia dichotoma were screened for their free radical scavenging properties using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and comparing it with butylated hydroxyl toluene (BHT) as standard antioxidant...

Mahasweta Roy*, Bhupendra Kumar, Nishant Kumar, Amrit Patel and Babita Kumar

College of Pharmacy, Shree Ganpati Institute of Technology, Ghaziabad, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2896-01

2896-2901

4206

1734

43.

ASSESSMENT OF C.S.J.M. UNIVERSITY CAMPUS STUDENTS AWARENESS AND ATTITUDE TOWARDS ANALGESICS (NSAIDs)

The present study was performed with an objective to assess knowledge, awareness, frequency indication and pattern of uses and attitude towards Non-Steroidal anti-inflammatory drugs (NSAIDs) among the scholars. In this survey based qualitative research, 591 respondents from the C.S.J.M. University campus, Kanpur, were screened out during the changing weather of north India (January–February 2013...

Ajay Kumar Gupta*, Arvind Kumar Jaiswal and Satyendra Kumar

University Institute of Pharmacy, C.S.J.M. University, Kanpur- 208 024, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(2).612-18

612-618

4206

1559

27.

EVALUATION OF JASMINUM GRANDIFLORUM FOR HEPATOPROTECTIVE ACTIVITY IN ISONIAZID INDUCED LIVER DAMAGE

Objectives: The study was designed to evaluate hepatoprotective effect of the ethanolic leaves extract of Jasminum grandiflorum (JG) in Isoniazid (INH) induced hepatotoxicity in wistar albino rats. Materials and methods: Mature leaves of JG were collected, authenticated and subjected to successive ethanolic extraction. Hepatic damage was induced in wistar rats by administering INH (54mg/kg, p.o...

Netranjali Dhamal, Mihir Patel and Shrikant Pawar*

Department of Pharmacology, Sinhgad Technical Education Society’s Smt. Kashibai Navale College of Pharmacy, Kondhwa, Pune-411048, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(8).2568-73

2568-2573

4205

1817

21.

ANTIMICROBIAL PROPERTIES OF DIFFERENT SOLVENTS EXTRACT OF RUMEX VESICARIUS LINN. ON SOME SELECTED BACTERIAL AND FUNGAL ISOLATES

The Antimicrobial (antifungal and antibacterial) properties of the different solvents extracts (benzene, pet ether, acetone, chloroform, methanol and aqueous) of Rumex vesicarius Linn plant plants, on four bacterial (Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus) and four fungal isolates (Aspergillus niger, Tricoderma reesei, Penicillium funiculosum and Fusa...

Ankita Shah*, Parul Sharma and Rekha Vijayvergia

Plant Pathology and Plant Biochemistry Laboratory, Department of Botany, University of Rajasthan, Jaipur-302004, India.

DOI: 10.13040/IJPSR.0975-8232.6(3).1107-14

1107-1114

4205

2004

27.

A CASE STUDY ON GLYCEMIC INDEX AND DIABETIC PERIPHERAL NEUROPATHY

The term HbA1c refers to glycated haemoglobin. By measuring glycated haemoglobin (HbA1c), clinicians are able to get an overall picture of what our average blood sugar levels have been over a period of weeks/months. Diabetic neuropathy is generally assessed in clinical practice by a combination of objective and subjective measures. Nerve conduction studies, the distal sural sensory nerves and the...

Arbind Kumar Choudhary * and Sadawarte Sahebrao Kishanrao

Department of Physiology, People’s College of Medical Sciences and Research Centre, Bhopal, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.6(11).4783-87

4783-87

4205

1579