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EFFECTS OF ALOE VERA ON LIVER OF SWISS ALBINO MICE AGAINST SUBLETHAL DOSE OF GAMMA RADIATION
The radioprotective effect of Aloe vera was studied in liver of Swiss albino mice. Animals were divided into three groups. Animals of group I administered double distilled water only, group-II Aloe vera (drug) and control set of group III were given radiation only where as animals experimental set of group III were administered by Aloe vera + Radiation. Animals were given Aloe vera leaf extract or...
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HEPATOPROTECTIVE ACTIVITY OF STEM BARK EXTRACT OF MANGIFERA INDICA L. ON CARBON TETRACHLORIDE-INDUCED HEPATIC INJURY IN WISTAR ALBINO RATS
The effects of aqueous stem bark extract of Mangifera indica in Carbon tetrachloride induced liver injury were investigated. In vivo animal models using Wistar albino rats was used in this experimental study. Carbon tetrachloride was successfully induced by significantly (P<0.001) increasing serum parameters AST, ALT, and ALP and decreasing serum total proteins and albumin levels (P<0.05). S...
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IN VITRO ANTIOXIDANT ACTIVITY OF CURCUMA AMADA ROXB.
A study was undertaken to evaluate the antioxidant potential of rhizomes of Curcuma amada (Zingiberaceae). Aqueous and ethanolic extracts were subjected to in vitro antioxidant activity screening models such as DPPH, ABTS, nitric oxide and inhibition of lipid peroxidation activity. Ascorbic acid was used as the standard. In all the models studied, both the extracts showed nearly equal activities...
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COMBINED EFFECTS OF ATORVASTATIN AND NICOTINE ON TESTICULAR EXPRESSION OF STEROIDOGENIC ENZYMES IN EXPERIMENTAL RATS
Nicotine and atorvastatin have indirect effects on reproductive function. So this study focused on changes in testosterone biosynthesis in rats co administered nicotine and atorvastatin. Rats were divided into 4 groups.(1) Control, (2) Atorvastatin (10 mg/Kg b.wt), (3) Nicotine (0.6 mg/Kg b.wt)and (4) Atorvastatin (10 mg/Kg b.wt) + nicotine (0.6 mg/Kg b.wt). After sixty days of treatment testicu...
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EFFICIENCY OF DIFFERENT SOLVENTS ON PHYTOCHEMISTRY PROFILE OF WATER MELON (CITRULLUS VULGARIS SCHRAD.) SEED EXTRACTS
Citrullus vulgaris Schrad. has occupied a popular place in the indigenous system of folk medicine because of its high nutritional and antioxidant properties. The study aims to elucidate the extractive yield percentage and screen the seed extracts of watermelon using different solvents for its phytochemical profile. The solvents selected were Methanol, Ethanol, Chloroform, Petroleum ether, Ethyl ac...
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ROLE OF AUTO FLUORESCENCE IN APOPTOSIS ANALYSIS OF MCF-7 AND MDA-MB231 HUMAN BREAST CARCINOMAS TREATED WITH THYMOQUINONE
Thymoquinone (TQ) is the major active component of black seed essential oil which possess encouraging effects against cancer cells. The antitumor activities of TQ were verified in breast carcinoma in-vitro and in-vivo. Most of the times, the cellular responses to apoptosis, after TQ treatment, are evaluate by flow cytometry using annexin V-propidium iodide (PI) staining method. Although flow cytom...
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COMPARISON OF SURGICAL SITE INFECTION RATE BETWEEN ANTIBACTERIAL COATED SURGICAL SUTURE AND CONVENTIONAL SUTURE: A RANDOMIZED CONTROLLED SINGLE CENTRE STUDY FOR PREVENTIVE MEASURE OF POSTOPERATIVE INFECTION
The main objective of this study is to compare the reduction rate of surgical site infection (SSI) between Triclosan coated (TC) and conventional surgical (CS) suture postoperatively. Surgical site infection (SSI) can be presented as a major challenge for people in the sense of mortality and morbidity mostly in developing countries. The result of SSI with antibacterial suture in developed countrie...
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PRODUCTION AND PURIFICATION STRATEGIES FOR LACCASE
Laccase belongs to polyphenol oxidases, which is a very wide family of copper-containing atoms in the center, which serves as the catalytic site. It is biochemically a glycoprotein with molecular mass being between 50kda to 130kda and 30% carbohydrate content, in addition to this it has three types of copper atoms. It is one of the most important enzymes due to its role in the food industry. It ac...
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ANTIDIABETIC AND ANTI-INFLAMMATORY ACTIVITY OF UTICA DIOICA LEAVES ON STZ INDUCED TYPE 1 DIABETIC MODEL RATS
In the present study we have explored the effect of Urtica dioica, a traditional antidiabetic herb used in India and Bangladesh, on insulinemic and chronic inflammatory status of type 1 diabetic model rats. The mature and fresh leaves of U. dioica was collected from the mountain range of Assam in India and the water extract of the leaves was used at a dose of 1.25g/kg body weight. Adult Long-Evans...
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ANTIOXIDANT ACTIVITY OF THE ENDOPHYTIC FUNGI ISOLATED FROM MANGROVE ENVIRONMENT OF KARANKADU, RAMANATHAPURAM DISTRICT
Antioxidant property of Phomopsis amygdali culture filtrate extracted with ethanol, was evaluated in vitro. ABTS and DPPH radicals were used to evaluate their antioxidant activity. Antioxidant components like total phenol and flavonoid were also determined. The ethanolic extract of Phomopsis amygdali showed potent antioxidant activity against both ABTS and DPPH radicals with the EC50 value of 58...
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