Most Popular
CYTOLOGICAL STUDIES OF TWO SPECIES OF GENUS DELONIX
Many cytological characteristics were studied in two species of Genus Delonix i.e., D. regia and D. elata . Delonix regia possessed 2n = 28 chromosome number. Both univalent as well as bivalents occurred invariably in this plant species, the former type being predominant over latter type. The chiasma frequency per PMc varied from 8-12 with average being 15.82. The chiasma frequency per chromosom...
3020
1010
CLINICOPATHOLOGICAL STUDY OF 115 CASES OF GLIOBLASTOMA MULTIFORME WITH SPECIAL REFERENCE TO GLIOSARCOMA
Background: Glioblastoma Multiforme is the commonest of all astrocytomas. It accounts for 12-15% of all intracranial neoplasm and 50-60% of all astrocytic tumors. Most common site of occurrence is cerebrum and age incidence is highest in fifth and sixth decade. Gliosarcoma constitutes 2% of all brain tumors, 5% of all astrocytomas and 8% of anaplastic astrocytomas. The cell of origin of sarcomatou...
3020
875
DEVELOPMENT AND EVALUATION OF PUSH-PULL BASED OSMOTIC DELIVERY SYSTEM FOR ROPINIROLE
Ropinirole hydrochloride is indicated in Parkinson’s disease and Restless leg syndrome. In advanced Parkinson’s disease the usual dose of Ropinirole hydrochloride is 0.25 to 5 mg three to four times a day. Hence, an attempt was made to develop a once-a-day controlled release Osmotic drug delivery system. This may offer significant patient benefits by providing enhanced efficacy and reduced sid...
3020
1207
HYPOGLYCEMIC EFFECT OF 2-HYDROXYCHALCONE ON HIGH FRUCTOSE FED DIABETIC RAT
The objective of the project work was to study the effect of Hypoglycemic and Hypolipidemic activity of 2- hydroxychalcone on high fructose diet induced insulin resistance in male Wister Albino rats. Rats were rendered insulin resistant by feeding 66% (w/w) fructose and 1.1% (v/w) coconut oil mixed with normal pellet diet (NPD) for 3 weeks. Insulin resistance high fructose diabetic rats receiving ...
3019
1079
PROTECTIVE EFFECT OF QUERCETIN ON BISPHENOL A – INDUCED ENZYMATIC CHANGES IN TESTIS OF MICE
Bisphenol A is well known endocrine disturbing chemical. Evidence has demonstrated that exposure to certain levels can cause toxic effect in humans and laboratory animal models. Quercetin is consistently the most active of the flavonoids in experimental studies. The present investigation was an attempt to evaluate the effect of Bisphenol A on testis and its amelioration by quercetin. Inbred Swiss ...
3019
992
ROLE OF THE INCRETINS IN HYPOGLYCEMIC EFFECT OF PHLOGACANTHUS THYRSIFLORUS NEES IN CHEMICALLY INDUCED DIABETIC MICE
Objective: This study was aimed to evaluate the role of GLP-1, GIP in the hypoglycemic activity of Phlogacanthus thyrsiflorus Nees. Materials and Methods: We have evaluated the influence of Phlogacanthus thyrsiflorus Nees, a traditionally used antidiabetic medicinal plant on some metabolic parameters, glucose homeostasis, insulin production, glucagon like peptide 1 (GLP1) and gastric Inhibitory Po...
3018
1416
BIOEFFACY OF TWO TRADITIONAL BOTANICAL INSECTICIDES AGAINST HUMAN HEAD LICE
Two plants, Spilanthes acmella and Boenninghausenia albiflora used against the insect Pediculus humanus by the Gaddi tribals of Himachal Pradesh were presently tested for their insecticidal activity. The methanolic extracts of these plants were prepared from different parts of the plant collected in different months of the year since the active principle is known to vary in different parts of the ...
3017
1101
OLIBANUM RESIN BASED AMBROXOL HYDROCHLORIDE TABLETS: FABRICATION AND IN VITRO EVALUATION
Present era meant for utilization of natural resources in the development of dosage forms. In the present investigation natural biodegradable polymer olibanum resin is employed to develop matrix tablets of ambroxol hydrochloride for sustained release. Various Ratios of resins is study its ability to retard the early release of the drug from formulation. The tablets were prepared by wet granulation...
3017
1145
ISOLATION OF PRELIMINARY PHYTOCONSTITUENTS AND ANTI-INFLAMMATORY AND ANTIPYRETIC ACTIVITY OF CALOTROPIS GIGANTEA LINN. LEAVES EXTRACTS
The present studies that Isolation of preliminary phytoconstituents and anti-inflammatory and antipyretic activity of Calotropis gigantea Linn. Leaves Extracts. Therapeutic use of plants for the treatment of human illnesses dates back over man millennia. Evidence of their effectiveness in the diagnosis, cure and prevention of disease states exists in every culture throughout the world. Today “...
3016
1905
SYNTHESIS AND DOCKING STUDIES OF 2-AMINOTHIAZOLE-5-AROMATIC CARBOXAMIDE DERIVATIVES
A novel N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-pipear azinyl]-2-methyl-4-pyrimidinyl] amino]-5-thiazolecarboxamide derivatives (6a-6d) and (8a-8b) were synthesized by coupling 2-[(6-chloro-2-methylpyrimidin-4ylamino]-N-(2-chloro-6-methylphenyl) thiazole-5-Carboxamide(3) with Piperazine derivatives(4,7) in butanol and DIPEA (Diisopropylethylamine) at 120ºC for 4-5hrs. All th...
3015
1110