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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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70.

INVESTIGATION OF IN-VITRO THROMBOLYTIC AND IN-VIVO ANTIPYRETIC, ANTIDEPRESSANT POTENTIALITY AND ANALGESIC ACTIVITY WITH PHYTO-CHEMICAL NATURE OF METHANOLIC EXTRACT OF NYMPHOIDES HYDROPHYLLA

Nymphoides hydrophylla (NH) is mainly an aquatic herb of Menynthaceae family and traditionally used to treat fever, insect bites, different ulcers, and also to wash skin, where parasitic affection occurs. In this study, methanolic extract of Nymphoides hydrophylla (NH) plant was examined for the determination of thrombolytic, antipyretic, Central Nervous System (CNS) and analgesic activities. The ...

S. Bhattacharjee, S. Roy, M. M. Hosen, A. Das, T. D. Aka, S. C. Paul * and S. R. Debi

Department of Applied Chemistry and Chemical Engineering, Noakhali Science and Technology University, Sonapur, Noakhali, Bangladesh.

DOI: 10.13040/IJPSR.0975-8232.10(5).2619-27

2619-2627

4194

1340

3.

TOWARDS SUCCESSFUL ADAPTATION OF PLASMODIUM KNOWLESI TO LONG-TERM IN-VITRO CULTURE IN HUMAN ERYTHROCYTES

Plasmodium knowlesi, a simian malaria parasite, is widely used as a malaria model and now characterized as a clinically significant parasite that can lead to outbreaks throughout most countries in Southeast Asia. Despite its importance, both fundamental and clinical studies of P. knowlesi have been impeded by the lack of a convenient in-vitro culture system partly due to the parasite’s preferenc...

F. S. Mohamad and N. Abu-Bakar *

School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

DOI: 10.13040/IJPSR.0975-8232.10(6).2663-69

2663-2669

4194

1742

40.

SURVEILLANCE AND ASSESSMENT OF ADVERSE DRUG REACTIONS AND COMPARISON WITH THE RETROSPECTIVE STUDIES IN A SECONDARY CARE HOSPITAL

Adverse drug reactions are considered to be among the leading causes of morbidity and mortality. Approximately 5-25% of hospital admissions are due to ADR’s, and 6-15% of hospitalized patients experience serious adverse drug reactions (SADR’s), causing significant prolongation of hospital stay. The adverse drug reactions reported were classified based on Wills and Brown classification, Causali...

K. Moudgil, D. N. Chandu, A. Hamid and P. R. A. Vijayakumar *

Department of Pharmacy Practice, JSS College of Pharmacy, Ooty, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(7).3434-39

3434-3439

4194

2104

9.

STUDY OF DIFFERENT PROCESSING PARAMETERS FOR POLYLACTIC ACID MICROSPHERES FORMULATIONS

To evaluate the effects of different processing parameters on drug-loaded microspheres, the solvent evaporation technique was chosen as the formulation method. Indomethacin-loaded Polylactic acid microspheres were prepared by varying drug masses, then by changing the stirring speed. They were analyzed for their drug content, physical morphology, size, polymer-drug physicochemical compatibility, an...

D. Moussa, R. Kassab * and P. Yammine

Department of Chemistry, Faculty of Sciences, University of Balamand, Tripoli, Lebanon.

DOI: 10.13040/IJPSR.0975-8232.5(10).4176-81

4176-4181

4193

1453

23.

FORMULATION AND EVALUATION OF ACECLOFENAC MATRIX TABLETS USING SOLID DISPERSED PRODUCT

Aceclofenac is a non-steroidal anti-inflammatory drug indicated for symptomatic treatment of pain and inflammation. Aceclofenac is a BCS Class II drug with low solubility and high permeability, thus solid dispersion is one of the promising techniques used for enhancement of solubility and dissolution rate. The intent of the present study was to formulate and evaluate aceclofenac matrix tablets by ...

Revati Dharampal Sagare * and Udaykumar B. Bolmal

Department of Pharmaceutics, KLE College of Pharmacy, Vidyanagar, Hubli, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.13(3).1231-40

1231-1240

4193

1890

50.

INVESTIGATION OF EFFECT OF MURRAYA KOENIGII ON BIOPHYSICAL AND BIOCHEMICAL PARAMETERS OF WOUND IN DIABETIC HYPERLIPIDEMIC WISTAR RATS

Plants have been used in traditional medicine for several thousand years. India is perhaps the largest producer of medicinal herbs and is rightly called the “Botanical garden of the World”. Murraya koenigii Linn. commonly known as Meethi neem, belongs to the family Rutaceae. The curry tree is native to India and it is found almost everywhere in the Indian subcontinent excluding the higher leve...

Vikram Kumar*, Angshu Bandyopadhyayand Vikram Sharma

Research Scholar, Faculty of Pharmacy, CMJ University, Shillong- 793 003, Meghalaya, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(6).1839-45

1839-1845

4192

1656

24.

A SHORT TERM PROSPECTIVE, INTERVENTIONAL, COMPARATIVE CLINICAL STUDY FOR EVALUATION OF RAMIPRIL VERSUS TELMISARTAN IN HYPERTENSIVE PATIENTS WITH TYPE 2 DIABETES MELLITUS

Aim: To comparatively evaluate the antihypertensive efficacy and tolerability of ramipril and telmisartan in stage 1 hypertensive diabetic patients. Material and Methods: This short term, prospective, randomized, interventional, comparative clinical study was conducted amongst 53 patients of stage 1 hypertension with type 2 diabetes (27 ramipril and 26 telmisartan patients), aged 30 years and abov...

Pankaj Kumar , A. K. Kapoor *, H. K. Singh and M. Kulshrestha

Department of Pharmacology, Rohilkhand Medical College & Hospital, Bareilly (U.P.), India

DOI: 10.13040/IJPSR.0975-8232.6(8).3327-33

3327-33

4192

1551

25.

IDENTIFICATION OF AEROTOLERENCE GENE BATA AND BATB IN SUBGINGIVAL MICROFLORA: AGGREGATIBACTER ACTINOMYCETEMCOMITANS, TANNERELLA FORSYTHIA AND PREVOTELLA INTERMEDIA

Subgingival obligate anaerobes present within the biofilm such as Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia and Aggregati bacter actinomycetemcomitans have been implicated in the initiation and progression of periodontal disease. Recent documentation has demonstrated that P.gingivalis is capable of maintaining its viability when exposed to oxidative stress by expressing...

H. Parthsarathy, R. Gad and C. A. Jacob *

Department of Periodontology, Saveetha Dental College, Chennai, TN, India

DOI: 10.13040/IJPSR.0975-8232.7(2).689-96

689-96

4192

1941

20.

CRUDE ROOT EXTRACT OF ASPARAGUS RACEMOSUS AMELIORATES ACETAMINOPHEN INDUCED UREMIC RATS.

Now days, herbal medicines are widely used to treat, manage and cure the kidney diseases as well as reduce uremia, acute nephritis & nephritic syndrome. The present study was to evaluate the antiuremic and antioxidative effect of Asparagus racemosus (AR) on acetaminophen induced uremic male rats. The study was designed with 36 male albino rats which were randomly divided into 6 groups. Group I...

Suchismita Roy, Koushik Das, Shreya Mandal, Shrabani Pradhan, Arpita Patra and Dilip Kumar Nandi*

Research Unit, Developed by Department of Nutrition, Physiology & Microbiology, Raja N. L. Khan Women’s College, Midnapore-721102, Dist- Paschim Medinipur, West Bengal, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(8).3004-12

3004-3012

4191

1628

68.

BIOCHEMICAL STUDIES ON THE ANTI-ULCEROGENIC POTENTIAL OF CARDIOSPERMUM HALICACABUM L. SEEDS

Cardiospermum halicacabum L. var. microcarpum (Kunth) Blume and var. luridum (Blume) Adelb. (Sapindaceae) are used for various ailments in Indian traditional medicines. The present study evaluated the antiulcerogenic property of seed oils (Petroleum ether extracts) in animal model. Ethanol induced gastric ulcers was used for this study and analysed for gastric volume, ulcer score pH, free and tota...

G. Jayanthi*, T. Sathishkumar , T. Senthilkumar and M. Jegadeesan

Department of Botany, Vellalar College for Women (Autonomous), Erode- 638012, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(12).5038-43

5037-5043

4191

1598