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EFFECTS OF PREMNA INTEGRIFOLIA LINN. ROOTS EXTRACTS IN CCL4 INDUCED TOXICITY IN RATS
Premna integrifolia Linn. roots are used in the Indian system of medicine for the treatment of diabetes, inflammation, liver disorders etc. The present study was aimed to investigate the antioxidant activity of Premna integrifolia L. (Family: Verbenaceae) in CCl4 (carbon tetrachloride) induced oxidative stress in Sprague- Dawley rats. CCl4 injection induced oxidative stress by a significant rise i...
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PROTECTIVE EFFICACY OF ALLIUM SATIVUM ON DELTAMETHRIN INDUCED TOXICITY IN REPRODUCTIVE TISSUES OF MALE MICE
Present study was carried out to assess testicular toxicity of pyrethroid insecticide, Deltamethrin (DM) in male Swiss albino mice, Mus musculus and to evaluate protective role of Allium sativum (AS) in alleviating the detrimental effect of DM. Forty male mice were divided into five experimental groups (8 mice per group) and were categorized : Control- Given distilled water and food ad libitum, Ve...
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A CASE STUDY ON GLYCEMIC INDEX AND DIABETIC PERIPHERAL NEUROPATHY
The term HbA1c refers to glycated haemoglobin. By measuring glycated haemoglobin (HbA1c), clinicians are able to get an overall picture of what our average blood sugar levels have been over a period of weeks/months. Diabetic neuropathy is generally assessed in clinical practice by a combination of objective and subjective measures. Nerve conduction studies, the distal sural sensory nerves and the...
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THE EFFECT OF FORMULA TO PHYSICAL PROPERTIES OF WOUND HEALING GEL OF ETHANOLIC EXTRACT OF BINAHONG (ANREDERA CORDIFOLIA (TEN) STEENIS)
Binahong (Anredera cordifolia (Ten) Steenis) has been used as wound healing in traditional Indonesian medicine and it is relevant to develop dosage forms of binahong using formulation technology approach. The aim of this research was to find out wound healing gel formula of ethanolic extract of binahong. The factorial design method 3 factors and 2 levels were employed to achieve this study. Three ...
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COMPARATIVE STUDY OF BRAND AND GENERICS OF OMEPRAZOLE CAPSULES AVAILABLE IN THE SAUDI MARKET
Proton Pump Inhibitors (PPIs) are widely used acid suppression medications for many conditions. PPIs class includes many drugs, such as omeprazole, lansoprazole, pantoprazole and esomeprazole, available orally in a tablet/capsule form. PPI’s products have reasonably high prices with quality differences that most healthcare providers must know. Therefore, this study aimed to compare the quality o...
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EVALUATION OF STRESS IN EXPERIMENTAL PHARMACOLOGY
Stress undoubtedly has become an integral part of human life. Stressful conditions have a derogative effect on normal physiological functions leading to a variety of disease states. Many of the most prevalent diseases of the modern era like hypertension, diabetes, behavioral disorders, etc. have been implicated as one of the many ill-effects of chronic stress. Experimental models are required to b...
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IN-VITRO EVALUATION OF ANTIOXIDANT ACTIVITY AND TOTAL PHENOLIC CONTENT OF TYLOPHORA INDICA (BURM F.) MERILL
Tylophora indica is a perennial climbing plant native to India, found in plains, forests, hills of southern and eastern India. The portions of plant used medicinally are leaves. The Total phenolic content of methanolic leaves extract was estimated by Folin-Ciocalteu assay method, and was found to be 0.160 mg/CE/g (Catechine Equivalent per gram). However, antioxidant activity of methanolic leaves e...
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BARRIERS TO IMPLEMENTATION OF PERFORMANCE-BASED MANAGEMENT PRACTICES IN PHARMACIES IN A DEVELOPING COUNTRY
The objective of this study was to conduct a survey and determine the barriers to implement performance-based management in pharmacies in Trinidad. PBM is defined as “a systematic approach to performance improvement through an on-going process of establishing strategic performance objectives, measuring performance, collecting, analyzing, reviewing, and reporting performance data, and using that ...
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COMPARISON OF BLUMEA DENSIFLORA AND SALVINIA CUCULLATA LEAVES FOR THEIR ANTHELMENTIC ACTIVITY BY USING PHERETIMA POSTHUMA
Plant derived drug molecules are frequently showing their role in treating the disease conditions with minimal side effects comparing to the synthetic molecules. Forest and trees are natural assets that provide a variety of benefits to the mankind. Currently available anthelmintic drugs require improved management, high cost and also worms developing resistance to these drugs. So, there is a need ...
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NANOCARRIERS: A NOVEL TREATMENT APPROACH FOR ARTHRITIS
Arthritis is a major cause of disability conventionally treated for long term with nonsteroidal anti-inflammatory drugs and corticosteroids. NSAIDs are nonselective inhibitors of cyclooxygenase and cause GI toxicity, antiplatelet effects, cardiotoxicity, renal toxicity and anaphylactic reactions in selected patients. Corticosteroids have multiple side effects, including gastrointestinal bleeding, ...
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