Most Popular
SPECTROPHOTOMETIC ANALYSIS OF GATIFLOXACIN TABLETS USING MIXED HYDROTROPHY
A new, simple, safe, accurate and reproducible spectrophotometric analytical method was developed for the quantitative estimation of gatifloxacin in solid dosage form by mixed hydrotropic agents. The enhancement of solubility of drug gatifloxacin was more than 15 fold in mixed hydrotropic solution (20% N,N dimethyl urea and 20% sodium citrate solution) as compared to solubility in distilled wate...
3044
1071
NEUTRALIZATION OF TOXINS IN AQUA CULTURE USING PROBIOTICS
Bioremediation is a waste management method where we can employ different types of microorganism’s to nullify the effect of pollutants from a contaminated site. In the current study the authors have carried out a three months study to find out how different bacterial strains of Bacillus licheniformis, B. substilis and pseudomonas species can be used to assess the water quality in terms of pa...
3044
1084
FORMULATION, CHARACTERIZATION AND IN-VIVO APPLICATION OF ORAL INSULIN NANOTECHNOLOGY USING DIFFERENT BIODEGRADABLE POLYMERS: ADVANCED DRUG DELIVERY SYSTEM
The overall objective of this research is to improve the oral bioavailability of insulin through encapsulation in nanoparticles formulated by "ionotropic pre-gelation followed by polyelectrolyte complexation technique". The preparation variables such as initial drug concentration, polymer: polymer ratios, crosslinker concentration, stirring speed, stirring time, pH of drug / polymer mixture were i...
3044
1136
A VALIDATED LC-MS/MS BIOANALYTICAL METHOD FOR THE SIMULTANEOUS DETERMINATION OF THREE ACE-INHIBITORS IN HUMAN PLASMA
A selective and rapid LC-MS/MS spectrophotometric method has been developed and validated for the simultaneous determination of three ACE-inhibitors used in anti-hypertensive therapy, namely enalapril maleate, perindopril, and ramipril in human plasma using high-performance liquid chromatography-tandem mass spectrophotometry (LC-MS/MS) with electrospray ionization (ESI). Separation of analytes and...
3044
1141
OPTIMIZATION STUDIES FOR ENHANCED BIOACTIVE METABOLITE PRODUCTION BY STREPTOMYCES VIOLACEORUBER VLK-4 ISOLATED FROM THE SOUTH COAST OF ANDHRA PRADESH, INDIA
The aim of the present study was to design the suitable culture medium and also optimize the culture conditions for enhanced production of antimicrobial metabolites by Streptomyces violaceoruber VLK-4 which exhibited a broad spectrum of activity against bacteria and fungi. Production of bioactive metabolites by the strain was high in modified yeast extract-malt extract dextrose (ISP-2) broth as co...
3043
1078
CELLULOSE AS SOLE SUBSTRATE FOR BIO ETHANOL PRODUCTION: DEVELOPMENT OF STRUCTURAL MOLECULAR MODEL OF ENDOGLUCANASE III FROM TRICHODERMA REESEI USING BIOINFORMATIC TOOLS
One of our greatest challenges in improving nation’s economy is to reduce the dependence on imported petroleum products. To accomplish this, we need a variety of alternative fuels, which includes ethanol produced from cellulosic materials. Cellulose is a rich natural biopolymer on earth and most dominating agricultural waste. Apart from the fossil fuels, bioethanol is used as chief renewable ene...
3043
1181
SYNTHESIS AND SPECTRAL STUDIES OF Ni(II) COMPLEXES WITH 2-HEPTANONESEMICARBAZONE AND 2-HETANONETHIOSEMICABAZONE
Complexes of Nickel(II) with 2-heptanonesemicarbazone (hsc) and 2-heptanonethiosemicabazone (htc) have been synthesized and characterized by elemental analysis, molar conductance measurements, magnetic moments, mass, IR and electronic/spectral studies. Synthesized complexes were found to have a general composition of Ni(L)2X2 (where X=Cl-, 1/2SO42-, NO3-, ClO4-, NCS-, CH3COO- and L=hsc or htc). Mo...
3043
1189
IN-VITRO ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF PITURANTHOS CHLORANTHUS AND ARTEMISIA VULGARIS FROM TUNISIA
Pituranthos chloranthus and Artemisia vulgaris L. are two of the most important aromatic and medicinal species from the Apiaceae and Asteraceae families, respectively. They are traditionally used in certain pathologies in which inflammatory processes are involved. The present study investigates the potential of aqueous extracts of Tunisian P. chloranthus and A. vulgaris as a natural alternative so...
3043
1160
STUDIES ON ALLERGENS CAUSING BRONCHIAL ASTHMA AND ALLERGIC RHINITIS
The studies on allergen causing bronchial asthma and allergic rhinitis were done by testing Immunoglobulin E level and absolute Eosinophil count to clinical patients in JEBI laboratory. The patients were from urban and rural areas, comprising both males and females in all age groups. Out of 613 patients, 523 patients were having markedly increased IgE level and 147 patients were found increased ...
3042
1127
ANALYTICAL CHARACTERIZATION OF A CONTROLLED RELEASE POLYMERIC SUSPENSION
Aims: Qualitative analysis of a mucoadhesive polymeric (Carbopol940) suspension of Norfloxacin was carried out with the aim of developing an oral controlled release gastro-retentive dosage form. Methods: The characterization of ultrasonicated formulation was performed by Fourier Transform Infrared Spectroscopy (FTIR), Raman Spectroscopy, X-ray powder diffraction (XRD) and Scanning electron micr...
3041
925