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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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23.

DRUG USE EVALUATION OF SHENMAI INJECTION IN THE FIRST AFFILIATED HOSPITAL OF BENGBU MEDICAL COLLEGE: A PROSPECTIVE ANALYSIS

Introduction: To investigate the evaluation pattern of Traditional Chinese medicine injection, establish the drug use evaluation(DUE) standards of shenmai injection, and implement of DUE programs of shenmai injection in the First Affiliated Hospital of Bengbu Medical College. Methods: Three hundred and thirty four patients were included in this retrospective analysis. The study duration was divide...

Qingping Shi*, Feng Ding , Ran Sang , Yan Liu and Haoyu Yuan

Department of Pharmacy, the first Affiliated Hospital of Bengbu Medical College, Bengbu 233004, China

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(1).225-30

225-230

2963

1030

39.

SIMULTANEOUS DETERMINATION OF PHENOLIC COMPOUNDS IN CATHARANTHUS ROSEUS LEAVES BY HPLC METHOD

In Catharanthus roseus, Rutin, Quercetin and Kaempferol are the most important phenolic compounds with antioxidant activity. For simultaneous determination of Rutin, Quercetin and Kaempferol in Catharanthus roseus a simple and rapid HPLC method was developed. Phosphate buffer (pH=5.8) and solvent Acetonitrile are used in ratio of 55: 45 as mobile phase. Rutin, Quercetin and Kaempferol were determi...

A. Srinivasa Rao* and Mohammed Fazil Ahmed

Bhaskar Pharmacy College, Yeknapally, Moinabad (Mandal), R.R (Dist), Hyderabad 500075, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(3).976-81

977-881

2962

1333

51.

FORMULATION AND IN-VITRO EVALUATION OF ACECLOFENAC ORODISPERSIBLE TABLETS

The object of the study was to formulate and evaluate Aceclofenac orodispersible tablets (ODT) by wet granulation method using different super disintegrants in different concentrations. Orodispersible tablets produce rapid dissolution of drug and absorption thereby producing rapid onset of action. Five batches (AFD1, AFD2, AFD3, AFD4, AFD5) of Aceclofenac orodispersible tablets were prepared and c...

S. Dharani*, K. Ramesh kumar, k. Elango, S. Hemalatha, P. Stephen and I. Nishanth

Department of Pharmaceutics, College of Pharmacy, Madras Medical College, Chennai-600003, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(1).407-10

407-410

2962

1145

26.

ANTI-INFLAMMATORY ACTIVITY OF SAMADERA INDICA LEAVES BY MEMBRANE STABILIZATION

The present work aims at evaluating the anti-inflammatory activity of Samadera indica by HRBC membrane stabilization. The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti-inflammatory activity. The anti-inflammatory activity of the crude ethanol extract, aqueous extract of leaves part of Samadera indica were compared to that of the standard drug diclofenac....

G.R. Rajalakshmi* and Jyoti Harindran

Research Scholar, Karpagam University, Karpagam, Coimbatore, Tamil Nadu-641021, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(2).721-23

721-723

2962

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38.

A RETROSPECTIVE STUDY OF PRESCRIBING PATTERN FOR ACUTE RESPIRATORY INFECTIONS IN CHILDERN IN A TERTIARY CARE TEACHING HOSPITAL

Objective: To study prescribing pattern for acute respiratory infections in children attending outpatient department of Paediatrics, J.L.N. Hospital, Ajmer, Rajasthan. Material and Method: The study was carried out retrospectively by analyzing the copies of prescriptions of patients who had visited the O.P.D. of the paediatrics department of J.L.N. Hospital Ajmer. A total of 350 prescriptions havi...

S. Sankhla*, S. Kanwar and D. K. Mahawar

JLN Medical College, Ajmer, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.8(9).3911-16

3911-3916

2962

959

31.

ANTIOXIDANT AND ANTICANCER ACTIVITIES OF ETHANOLIC EXTRACT OF FICUS GLOMERATA ROXB. IN DMBA INDUCED RATS

The present study was designed to evaluate the antioxidant and anticancer activities of the ethanolic leaf extract of Ficus glomerata Roxb. on the basis of enzymatic and non-enzymatic antioxidants, xenobiotic enzymes and histopathological parameters in 7, 12- dimethylbenz(a)anthracene (DMBA) induced mammary carcinoma in rats. F. glomerata is large evergreen tree, found all over India and South Eas...

V. Dhana Rangesh Kumar*, G. Jayanthi, K. Gurusamy and S. Gowri

Ph. D Research Scholar, Department of Biochemistry, Dr. N.G.P. College of Arts and Science, Coimbatore – 49, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(8).3087-93

3087-3093

2961

1152

37.

DIFFERENCE BETWEEN NATIVE AND MUTANT RHIZOBIUM ON GROWTH OF VIGNA MUNGO L.

The present study, carry out the use of plant growth promoting rhizobacteria, were used to improve the yield in crop. The Rhizobium strains isolated from legumes plant Mimosa pudica L and this strain was mutated by using UV radiation. The plant growth hormones were detected by native as well as mutant Rhizobium strains by paper chromatography techniques. The same strains use in conducted to green ...

Shijila Rani AS, P. Parthiban * and V. Mahesh

Department of Microbiology, Marudupandiyar College, Vallam, Thanjavur, Tamilnadu, India

DOI: 10.13040/IJPSR.0975-8232.7(9).3848-51

3848-51

2961

1174

58.

FORMULATION DESIGN OF EMPAGLIFLOZIN AND METFORMIN HYDROCHLORIDE EXTENDED RELEASE TABLETS: OPTIMIZATION OF FORMULATION USING STATISTICAL EXPERIMENTAL DESIGN

The objective of the present study was to develop Empagliflozin and Metformin hydrochloride extended release tablets, comprising immediate release empagliflozin and extended release metformin hydrochloride in a single tablet. Wet granulation process was employed to develop extended release part metformin hydrochloride. Impact of various formulation variables in extended release part was assessed u...

R. Chinta * and R. Pilli

Department of Pharmaceutics, University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(12).6434-47

6434-6447

2961

1607

3.

TRANSIENT RECEPTOR POTENTIAL (TRP) CHANNEL: AN EMERGING TARGET FOR PAIN

Pain perception begins with the activation of primary sensory nociceptors. Over the past decade, flourishing research has revealed that members of the Transient Receptor Potential (TRP) ion channel family are fundamental molecules that detect noxious stimuli and transduce a diverse range of physical and chemical energy into action potentials in somatosensory nociceptors. Here we highlight the role...

S. S. Khot*, H.Y. Shaikh and R.S. Patil

Core Vaccine Research Unit (CVRU), Vadu Rural Health Program, KEM Hospital Research Centre, Sardar Moodliar Road, Rasta peth, Pune- 411011, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(6).2035-44

2035-2044

2959

1020

29.

ANTIOXIDANT POTENTIAL OF TRAGIA INVOLUCRATA LINN ON STREPTOZOTOCIN INDUCED OXIDATIVE STRESS IN RATS

In Traditional Ayurvedic system of treatment Tragia involucrata Linn. is intended to use for diabetic patients has been screened for antioxidant activity. For antioxidant studies, aqueous ethanolic extract of Tragia involucrata (AEETI) was administered orally for 28 days at a dose of 250 and 500 mg/kg body weight to Streptozotocin- Nicotinamide induced Wistar rats. All the animals were sacrificed ...

S. Mohamed Farook* and W. Clement Atlee

Department of Pharmacology, C. L. Baid Metha College of Pharmacy, Thuraipakam, Chennai, Tamil Nadu, India

DOI: 2http://dx.doi.org/10.13040/IJPSR.0975-8232.2(6).1530-36

1530-1536

2959

1133