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ASSESSMENT OF CYTOTOXICITY, ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITIES OF THE ETHYLACETATE EXTRACT OF CALLIANDRA PORTORICENSIS ROOT BARK
Calliandra portoricensis a medicinal plant, is widely use in the treatment/management of various diseases in Nigeria. The ethyl acetate extract of the Calliandra portoricensis root bark were tested to evaluate the cytotoxicity, antioxidant (in vitro) and free radical scavenging activity. The different assay methods, including total antioxidant activity, free radical (nitric oxide, hydroxyl radical...
3707
1815
IMPACT OF TEACHING CLINICAL ASPECTS OF CARDIOVASCULAR PHARMACOLOGY AT BEDSIDE
Introduction: Medical students of present era have to prove their efficiency in every step of life. To do so one has to become a competent doctor. This is possible only with the proper knowledge and application of the rational therapeutics in clinical practice. This can happen when the students are motivated and taught medicine in such a way that can produce better learning. The clinical aspect of...
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1385
ANAL CANAL CANCER TREATMENT BY CONCURRENT CHEMORADIOTHERAPY VERSUS RADIOTHERAPY ALONE: A COMPARATIVE STUDY
Aim: The aim of this retrospective study is analysis of results of patient treatment outcome when prescribing chemotherapy and radiotherapy as concomitant setup as compared to radiotherapy alone for patients with anal canal carcinoma and related complications of this mode of treatment. Materials and Methods: 24 patients of anal canal cancer (squamous cell carcinoma-17 and adenocarcinoma-7)of me...
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1683
SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF NEW BAYLIS-HILLMAN DERIVED NITRO METHYLENE IMIDAZOLE DERIVATIVES AS INSECTICIDAL AGENTS
A series of Baylis-Hillman derived N-cinnamyl substituted nitro methylene imidazole derivatives 4a-swere synthesizedfrom Baylis-Hillman acetates and nitro methylene imidazole compoundsand characterised by 1H NMR, IR, Mass and HRMS spectroscopy. Their insecticidal activities were evaluated against T. Castaneum and compared with a standard insecticide Permethrane. Preliminary biological activity tes...
3706
2074
STABILITY INDICATING RP – HPLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF AMLODIPINE AND CHLORTHALIDONE IN BULK AND TABLET DOSAGE FORM
The RP-HPLC stability-indicating assay method has been developed and validated for the estimation of the amlodipine and chlorthalidone in bulk and combined dosage form. The method was optimized by using the mobile phase as a mixture of 0.1% formic acid: methanol: acetonitrile in the ratio of (50:5:45 v/v) at pH 3 was adjusted with orthophosphoric acid. The method was carried out on the Octadecylsi...
3706
1600
ASSESSMENT OF INJECTION USE PRACTICES AND COMPLETENESS OF PRESCRIPTIONS: THE CASE OF AYDER REFERRAL HOSPITAL, MEKELLE, NORTHERN ETHIOPIA
Back Ground: Overuse of injections is considered as an important indicator of irrational prescribing pattern in a given health care setting owing to the invasive nature of such drug delivery system. Moreover, blood-borne diseases such as hepatitis B, hepatitis C and HIV/AIDS can be transmitted through unsafe injections due to poor injection practices and injection overuse. If the use of injectio...
3705
1516
EVALUATION OF ANTIADIPOGENESIS ACTIVITIES OF SELECTED SPECIES OF CARALLUMA R. BR., BOUCEROSIA WIGHT & ARN. AND PREGNANE STEROID ON CELL LINES.
Back ground: The study was designed to determine antiadipogenesis properties of crude methanolic extracts from four species of Caralluma R.Br. such as Caralluma adscendens (Roxb.) R. Brown var. attenuata (Wight) Grav. & Mayur. (CAA), Caralluma adscendens (Roxb.) R. Brown var. fimbriata (Wall.) Gravely & Mayur. (CAF), Caralluma stalagmifera C.E.C. Fisch. (CS) and Caralluma stalagmifera C.E....
3704
1981
EVALUATION OF ANTIBACTERIAL ACTIVITY OF APIS HONEYS FROM PADERU FOREST DIVISION IN ANDHRA PRADESH INDIA
Antibacterial activity of the two honey samples produced by the honey bee (Apis florea), was standardized by Disc diffusion method. The two honey samples were tested at three concentrations (5, 10 and 15µl v/v) and zone of inhibition were measured against Staphylococcus aureus, Escherichia coli, Basillus subitis, Pseudomonas putida and Klebsiela pneumonia; unifloral and multifloral honey samples ...
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1404
ISOLATION, SCREENING, CHARACTERIZATION AND DETERMINATION OF B-COMPLEX VITAMINS BY LACTOBACILLUS STRAINS FROM DIFFERENT SOURCES OF MEAT
In this study, isolation, screening, characterization, antibiotic susceptibility tests, curing & Determination of B-complex vitamin production by potent probiotic Lactobacillus strains from different sources of meat was analysed. 250 grams of intestine parts of goat meat and beef each were transferred to MRS broth to screen the potent probiotic Lactobacillus strains. Initially 57 strains were ...
3704
1713
IMPACTS OF HIGH DIETARY FAT ON SERUM CHOLESTEROL AND DEVELOPMENT OF FATTY LIVER IN RATS
The present study was designed to evaluate the impacts of high dietary fat on serum Total cholesterol and fatty liver syndrome in rats. Rats are fed on diets containing cholesterol; they develop fatty livers which are characterized by the presence in the liver of excessive amounts of cholesteryl esters, and glyceride. Increasement of glyceride content depend on a number of factors, such as the d...
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1358