Pages Menu
TwitterRssFacebookWhatsapplinkedin
ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

Categories Menu

Most Popular

 
Title
Views
PDF
Cited
27.

ANTIDIABETIC AND GLYCOGENESIS EFFECTS OF DIFFERENT FRACTIONS OF METHANOLIC EXTRACT OF MOMORDICA CHARANTIA (LINN.) IN ALLOXAN INDUCED DIABETIC RATS

The study was undertaken to investigate the antihyperglycemic, oral glucose tolerance test (OGTT) and glycogenesis effects of the different fractions (Petroleum ether, ethyl acetate and chloroform) of methanolic extract of Momordica charantia. The different fractions of the extract were administered intraperitoneally as a single dose of 150 mg/kg body weight to alloxan induced as well as glucose i...

M. S. Hossain*, M. Asadujjaman , M.R.I. Khan , M. Ahmed and A. Islam

Senior Lecturer, Department of Pharmacy, Atish Dipankar University of Science and Technology, House No. 83, Road No. 04, Banani, Dhaka Bangladesh

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(2).404-12

404-412

3626

1508

26.

EFFECT OF PLANT GROWTH REGULATORS ON SECONDARY METABOLITES ACCUMULATION AND ANTIOXIDANT ACTIVITY OF CATHARANTHUS ROSEUS L.

Secondary metabolites not only play a vital role in plant defense but also had shown various medicinal properties which provide a scientific base for using herbs and different plants as alternative medicines that were used by ancient communities. Many of the drugs today are simple synthetic modifications of the natural compounds. The developing commercial requirements of secondary metabolites in r...

B. A. J. Sidkey

Department of Biology, College of Science, University of Baghdad, Iraq.

DOI: 10.13040/IJPSR.0975-8232.11(1).241-45

241-245

3626

1527

20.

STUDY OF ELECTRODE KINETICS AND THERMODYNAMIC PARAMETERS OF TINIDAZOLE POLAROGRAPHYCALLY

The electrochemical reduction of anti- parasitic drug “Tinidazole” has been carried out in aqueous solution in the pH range 2.3 to 11.3 by Direct current (DC) polarography. Tinidazole exhibits one or two reduction peaks depending on pH. In basic medium one reduction peak was observed. Along with different pH, studies of drug have been carried out with different concentrations of drug and at di...

Ashish Garg*, Yogesh Kumar, Om Prakash Meena, Mahipat Singh and R. Pandey

Lab. No. 303, Department of Chemistry, University of Rajasthan, JLN Marg, Jaipur, Rajasthan, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(4).882-86

882-886

3625

1398

34.

GC–MS ANALYSIS OF ANTIOXIDANT COMPOUNDS PRESENT IN DIFFERENT EXTRACTS OF AN ENDEMIC PLANT DILLENIA SCABRELLA (DILLENIACEAE) LEAVES AND BARKS

The study aimed to investigate and characterize the antioxidant compounds from the leaves and barks of Dillenia scabrella (Dilleniaceae) (D. scabrella), an indigenous plant in the Northeast. The air-dried leaves and barks were powdered and subjected to selective sequential extraction using solvents of increasing polarity through percolation, namely, methanol, ethyl acetate + ethanol and water to o...

K. Momin and S. C. Thomas *

Department of Biosciences, Tapesia Campus, Assam Don Bosco University, Sonapur, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.11(5).2262-73

2262-2273

3625

2510

15.

IN VITRO SUSCEPTIBILITY OF PLASMODIUM FALCIPARUM TO LUMEFANTRINE AND ANALYSIS OF POLYMOPHYSIMS IN PFMDR-1 GENE ISOLATES FROM ABIDJAN (CÔTE D’IVOIRE)

Context: Malaria endemic disease remains the most common tropical parasitic disease in the world. According to the World Health Organization (WHO), malaria is the first endemic disease of which humanity is paying a heavy price. Malaria is a major public health problem in Côte d'Ivoire. Objective: To evaluate the in vitro chemosensitivity to Lumefantrine (LUM) and analyze Pfmdr-1gene polymorphism ...

Trebissou Jonhson Noel David* , Yavo William , Tano Konan Dominique , N’cho Monsan , Yapi Houphouet Felix , Djaman Allico Joseph

Pharmacodynamics Biochemical Laboratory, UFR Biosciences, Felix Houphouet Boigny, University, PO BOX, 582 Abidjan 22- Côte d’Ivoire

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(4).1732-38

1732-1738

3624

1418

39.

HIGH – PERFORMANCE LIQUID CHROMATOGRAPHY METHOD VALIDATION AND DEVELOPMENT STRATEGY FOR RIFABUTIN

A simple, economical, accurate and precise high performance liquid chromatographic method was developed and validated for the determination of rifabutin. A Shimadzu LC-2010C HT version 3.01 system using a C-18 column with dimensions of 250 × 4.6 mm and silica particle size of 5 μm. Isocratic elution was employed with methanol, acetonitrile and water (75:25 v/v) were used. The flow rate was 1 ml/...

G. Singh * and A. K. Srivastava

Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology, (Banaras Hindu University) Varanasi, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.9(9).3903-07

3903-3907

3624

1578

28.

SCHWANNOMA PRESENTING AS A GYNAECOLOGICAL MASS WITH PREGNANCY- A CASE REPORT

Schwannomas are usually benign tumors that result from the proliferation of the perineural cells. Since these tumors are very rare, misdiagnosis is common. Clinically, these tumors may present as a cranial neuropathy, abdominal or soft tissue mass, intracranial lesion, or with spinal cord compression. Histologically, these tumors are encapsulated, highly vascular, and composed of a homogenous patt...

N. Dahiya*, P. Dahiya , R. Kalra , S. Singh , N. Marwah and A. Paul

House No. 727/23, DLF Colony, Rohtak, Haryana, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(5).1276-79

1276-1279

3623

1596

46.

AN IN SILICO APPROACH TO IDENTIFY NEW ANTI-HIV INTEGRASE INHIBITOR LIKE LEADS BY DOCKING STUDIES

The Human immunodeficiency virus(HIV)type-1 integrase is one of the most important target of highly active anti retrovirus therapy (HAART), due toits role to incorporate genetic information into the host DNA, so its prevention to its proper function results in very fine therapeutic effect for the treatment of all acquired immune deficiency syndrome(AIDS), extensive research work on integrase inhib...

Rituraj *, K. K. Srivastava , Shubha Srivastava and Tanweer Alam

Department of Chemistry, Vinoba Bhave University, Hazaribagh, Jharkhand, India

DOI: 10.13040/IJPSR.0975-8232.6(10).4484-90

4484-90

3622

1780

30.

TARGETING INFLAMMATORY PROTEINS USING IMMUNOMODULATOR FOR REGULATION OF HEPATOCELLULAR CARCINOMA MICROENVIRONMENT

Inflammation plays fundamental role in hepatocellular carcinoma (HCC) initiation, progression and metastasis. The over expression of pro-inflammatory factors like Tumor necrosis factor-α (TNF-α), selectin, (IL)-6, nuclear factor-κB, TGF-β can alter the hepatic microvasculature. Natural products such as polyphenols, alkaloids, flavonoids, and flavonols have the ability to interface microenviron...

S. Mishra, K. Mittal, S. Hora, R. J. Mani and D. P. Katare*

Proteomics and Translational Research Lab, Centre for Medical Biotechnology, Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.8(11).4750-57

4750-4757

3622

1570

29.

SYNTHESIS NEW MOLECULARLY IMPRINTED POLYMERS FOR THE SELECTIVE ELECTRODES OF ISOPROPAMIDE FROM PHARMACEUTICAL SAMPLES

Liquid electrodes of polymers imprinted with Isopropamide (ISP) were synthesized based on precipitation polymerization mechanism. The molecularly imprinted polymer (MIP) and non-imprinted polymers (NIP) were synthesized using (ISP) as a template. In the polymerization process, 2-Hydroxyethyl meth acrylate (2-HEMA) and 2-Vinyl pyridine (2-VP) were used as monomers. Di-vinylbanzene (DVB) was used as...

A. M. Dhari * and Y. K. Al-Bayati

Department of Chemistry, College of Science, University of Baghdad, Al-Jadryia, Baghdad, Iraq.

DOI: 10.13040/IJPSR.0975-8232.10(6).2870-78

2870-2878

3622

1451